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2009 1
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18 results

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Page 1
Intrinsic Immunogenicity of Small Cell Lung Carcinoma Revealed by Its Cellular Plasticity.
Mahadevan NR, Knelson EH, Wolff JO, Vajdi A, Saigí M, Campisi M, Hong D, Thai TC, Piel B, Han S, Reinhold BB, Duke-Cohan JS, Poitras MJ, Taus LJ, Lizotte PH, Portell A, Quadros V, Santucci AD, Murayama T, Cañadas I, Kitajima S, Akitsu A, Fridrikh M, Watanabe H, Reardon B, Gokhale PC, Paweletz CP, Awad MM, Van Allen EM, Lako A, Wang XT, Chen B, Hong F, Sholl LM, Tolstorukov MY, Pfaff K, Jänne PA, Gjini E, Edwards R, Rodig S, Reinherz EL, Oser MG, Barbie DA. Mahadevan NR, et al. Among authors: akitsu a. Cancer Discov. 2021 Aug;11(8):1952-1969. doi: 10.1158/2159-8290.CD-20-0913. Epub 2021 Mar 11. Cancer Discov. 2021. PMID: 33707236 Free PMC article.
Pre-T cell receptor self-MHC sampling restricts thymocyte dedifferentiation.
Duke-Cohan JS, Akitsu A, Mallis RJ, Messier CM, Lizotte PH, Aster JC, Hwang W, Lang MJ, Reinherz EL. Duke-Cohan JS, et al. Among authors: akitsu a. Nature. 2023 Jan;613(7944):565-574. doi: 10.1038/s41586-022-05555-7. Epub 2022 Nov 21. Nature. 2023. PMID: 36410718 Free PMC article.
Parsing digital or analogue TCR performance through piconewton forces.
Akitsu A, Kobayashi E, Feng Y, Stephens HM, Brazin KN, Masi DJ, Kirpatrick EH, Mallis RJ, Duke-Cohan JS, Booker MA, Cinella V, Feng WW, Holliday EL, Lee JJ, Zienkiewicz KJ, Tolstorukov MY, Hwang W, Lang MJ, Reinherz EL. Akitsu A, et al. bioRxiv [Preprint]. 2023 Nov 30:2023.11.29.568292. doi: 10.1101/2023.11.29.568292. bioRxiv. 2023. Update in: Sci Adv. 2024 Aug 16;10(33):eado4313. doi: 10.1126/sciadv.ado4313 PMID: 38076892 Free PMC article. Updated. Preprint.
Parsing digital or analog TCR performance through piconewton forces.
Akitsu A, Kobayashi E, Feng Y, Stephens HM, Brazin KN, Masi DJ, Kirkpatrick EH, Mallis RJ, Duke-Cohan JS, Booker MA, Cinella V, Feng WW, Holliday EL, Lee JJ, Zienkiewicz KJ, Tolstorukov MY, Hwang W, Lang MJ, Reinherz EL. Akitsu A, et al. Sci Adv. 2024 Aug 16;10(33):eado4313. doi: 10.1126/sciadv.ado4313. Epub 2024 Aug 14. Sci Adv. 2024. PMID: 39141734 Free PMC article.
Pre-T cell receptors topologically sample self-ligands during thymocyte β-selection.
Li X, Mizsei R, Tan K, Mallis RJ, Duke-Cohan JS, Akitsu A, Tetteh PW, Dubey A, Hwang W, Wagner G, Lang MJ, Arthanari H, Wang JH, Reinherz EL. Li X, et al. Among authors: akitsu a. Science. 2021 Jan 8;371(6525):181-185. doi: 10.1126/science.abe0918. Epub 2020 Dec 17. Science. 2021. PMID: 33335016 Free PMC article.
T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitis.
Martin BN, Wang C, Zhang CJ, Kang Z, Gulen MF, Zepp JA, Zhao J, Bian G, Do JS, Min B, Pavicic PG Jr, El-Sanadi C, Fox PL, Akitsu A, Iwakura Y, Sarkar A, Wewers MD, Kaiser WJ, Mocarski ES, Rothenberg ME, Hise AG, Dubyak GR, Ransohoff RM, Li X. Martin BN, et al. Among authors: akitsu a. Nat Immunol. 2016 May;17(5):583-92. doi: 10.1038/ni.3389. Epub 2016 Mar 21. Nat Immunol. 2016. PMID: 26998763 Free PMC article.
Molecular design of the γδT cell receptor ectodomain encodes biologically fit ligand recognition in the absence of mechanosensing.
Mallis RJ, Duke-Cohan JS, Das DK, Akitsu A, Luoma AM, Banik D, Stephens HM, Tetteh PW, Castro CD, Krahnke S, Hussey RE, Lawney B, Brazin KN, Reche PA, Hwang W, Adams EJ, Lang MJ, Reinherz EL. Mallis RJ, et al. Among authors: akitsu a. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2023050118. doi: 10.1073/pnas.2023050118. Proc Natl Acad Sci U S A. 2021. PMID: 34172580 Free PMC article.
Potential role of myeloid cell/eosinophil-derived IL-17 in LPS-induced endotoxin shock.
Shimura E, Shibui A, Narushima S, Nambu A, Yamaguchi S, Akitsu A, Leonard WJ, Iwakura Y, Matsumoto K, Suto H, Okumura K, Sudo K, Nakae S. Shimura E, et al. Among authors: akitsu a. Biochem Biophys Res Commun. 2014 Oct 10;453(1):1-6. doi: 10.1016/j.bbrc.2014.09.004. Epub 2014 Sep 6. Biochem Biophys Res Commun. 2014. PMID: 25204502 Free PMC article.
The C-type lectin receptor Clec1A plays an important role in the development of experimental autoimmune encephalomyelitis by enhancing antigen presenting ability of dendritic cells and inducing inflammatory cytokine IL-17.
Makusheva Y, Chung SH, Akitsu A, Maeda N, Maruhashi T, Ye XQ, Kaifu T, Saijo S, Sun H, Han W, Tang C, Iwakura Y. Makusheva Y, et al. Among authors: akitsu a. Exp Anim. 2022 Aug 5;71(3):288-304. doi: 10.1538/expanim.21-0191. Epub 2022 May 8. Exp Anim. 2022. PMID: 35135958 Free PMC article.
18 results