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Human milk inhibits some enveloped virus infections, including SARS-CoV-2, in an intestinal model.
Aknouch I, Sridhar A, Freeze E, Giugliano FP, van Keulen BJ, Romijn M, Calitz C, García-Rodríguez I, Mulder L, Wildenberg ME, Muncan V, van Gils MJ, van Goudoever JB, Stittelaar KJ, Wolthers KC, Pajkrt D. Aknouch I, et al. Life Sci Alliance. 2022 Aug 4;5(12):e202201432. doi: 10.26508/lsa.202201432. Life Sci Alliance. 2022. PMID: 35926873 Free PMC article.
A Human 2D Primary Organoid-Derived Epithelial Monolayer Model to Study Host-Pathogen Interaction in the Small Intestine.
Roodsant T, Navis M, Aknouch I, Renes IB, van Elburg RM, Pajkrt D, Wolthers KC, Schultsz C, van der Ark KCH, Sridhar A, Muncan V. Roodsant T, et al. Among authors: aknouch i. Front Cell Infect Microbiol. 2020 Jun 9;10:272. doi: 10.3389/fcimb.2020.00272. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32656095 Free PMC article.
Assessment of the broad-spectrum host targeting antiviral efficacy of halofuginone hydrobromide in human airway, intestinal and brain organotypic models.
García-Rodríguez I, Moreni G, Capendale PE, Mulder L, Aknouch I, Vieira de Sá R, Johannesson N, Freeze E, van Eijk H, Koen G, Wolthers KC, Pajkrt D, Sridhar A, Calitz C. García-Rodríguez I, et al. Among authors: aknouch i. Antiviral Res. 2024 Feb;222:105798. doi: 10.1016/j.antiviral.2024.105798. Epub 2024 Jan 6. Antiviral Res. 2024. PMID: 38190972 Free article.
Amino acid variation at VP1-145 of enterovirus A71 determines the viral infectivity and receptor usage in a primary human intestinal model.
Aknouch I, García-Rodríguez I, Giugliano FP, Calitz C, Koen G, van Eijk H, Johannessson N, Rebers S, Brouwer L, Muncan V, Stittelaar KJ, Pajkrt D, Wolthers KC, Sridhar A. Aknouch I, et al. Front Microbiol. 2023 Apr 17;14:1045587. doi: 10.3389/fmicb.2023.1045587. eCollection 2023. Front Microbiol. 2023. PMID: 37138595 Free PMC article.