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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 1
2000 1
2001 2
2003 1
2004 1
2005 2
2006 2
2008 2
2009 1
2010 1
2011 5
2012 5
2013 8
2014 2
2015 3
2016 7
2017 5
2018 4
2019 6
2020 4
2021 7
2022 3
2023 2
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64 results
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Page 1
A comprehensive map of molecular drug targets.
Santos R, Ursu O, Gaulton A, Bento AP, Donadi RS, Bologa CG, Karlsson A, Al-Lazikani B, Hersey A, Oprea TI, Overington JP. Santos R, et al. Among authors: al lazikani b. Nat Rev Drug Discov. 2017 Jan;16(1):19-34. doi: 10.1038/nrd.2016.230. Epub 2016 Dec 2. Nat Rev Drug Discov. 2017. PMID: 27910877 Free PMC article. Review.
How many drug targets are there?
Overington JP, Al-Lazikani B, Hopkins AL. Overington JP, et al. Among authors: al lazikani b. Nat Rev Drug Discov. 2006 Dec;5(12):993-6. doi: 10.1038/nrd2199. Nat Rev Drug Discov. 2006. PMID: 17139284 Review.
Therapeutic opportunities within the DNA damage response.
Pearl LH, Schierz AC, Ward SE, Al-Lazikani B, Pearl FM. Pearl LH, et al. Among authors: al lazikani b. Nat Rev Cancer. 2015 Mar;15(3):166-80. doi: 10.1038/nrc3891. Nat Rev Cancer. 2015. PMID: 25709118 Free article. Review.
JMJD6 Is a Druggable Oxygenase That Regulates AR-V7 Expression in Prostate Cancer.
Paschalis A, Welti J, Neeb AJ, Yuan W, Figueiredo I, Pereira R, Ferreira A, Riisnaes R, Rodrigues DN, Jiménez-Vacas JM, Kim S, Uo T, Micco PD, Tumber A, Islam MS, Moesser MA, Abboud M, Kawamura A, Gurel B, Christova R, Gil VS, Buroni L, Crespo M, Miranda S, Lambros MB, Carreira S, Tunariu N, Alimonti A, Al-Lazikani B, Schofield CJ, Plymate SR, Sharp A, de Bono JS; , SU2C/PCF International Prostate Cancer Dream Team. Paschalis A, et al. Among authors: al lazikani b. Cancer Res. 2021 Feb 15;81(4):1087-1100. doi: 10.1158/0008-5472.CAN-20-1807. Cancer Res. 2021. PMID: 33822745 Free PMC article.
Protein structure prediction.
Al-Lazikani B, Jung J, Xiang Z, Honig B. Al-Lazikani B, et al. Curr Opin Chem Biol. 2001 Feb;5(1):51-6. doi: 10.1016/s1367-5931(00)00164-2. Curr Opin Chem Biol. 2001. PMID: 11166648 Review.
Target 2035 - update on the quest for a probe for every protein.
Müller S, Ackloo S, Al Chawaf A, Al-Lazikani B, Antolin A, Baell JB, Beck H, Beedie S, Betz UAK, Bezerra GA, Brennan PE, Brown D, Brown PJ, Bullock AN, Carter AJ, Chaikuad A, Chaineau M, Ciulli A, Collins I, Dreher J, Drewry D, Edfeldt K, Edwards AM, Egner U, Frye SV, Fuchs SM, Hall MD, Hartung IV, Hillisch A, Hitchcock SH, Homan E, Kannan N, Kiefer JR, Knapp S, Kostic M, Kubicek S, Leach AR, Lindemann S, Marsden BD, Matsui H, Meier JL, Merk D, Michel M, Morgan MR, Mueller-Fahrnow A, Owen DR, Perry BG, Rosenberg SH, Saikatendu KS, Schapira M, Scholten C, Sharma S, Simeonov A, Sundström M, Superti-Furga G, Todd MH, Tredup C, Vedadi M, von Delft F, Willson TM, Winter GE, Workman P, Arrowsmith CH. Müller S, et al. Among authors: al lazikani b. RSC Med Chem. 2021 Dec 3;13(1):13-21. doi: 10.1039/d1md00228g. eCollection 2022 Jan 27. RSC Med Chem. 2021. PMID: 35211674 Free PMC article.
canSAR chemistry registration and standardization pipeline.
Dolciami D, Villasclaras-Fernandez E, Kannas C, Meniconi M, Al-Lazikani B, Antolin AA. Dolciami D, et al. Among authors: al lazikani b. J Cheminform. 2022 May 28;14(1):28. doi: 10.1186/s13321-022-00606-7. J Cheminform. 2022. PMID: 35643512 Free PMC article.
Transforming cancer drug discovery with Big Data and AI.
Workman P, Antolin AA, Al-Lazikani B. Workman P, et al. Among authors: al lazikani b. Expert Opin Drug Discov. 2019 Nov;14(11):1089-1095. doi: 10.1080/17460441.2019.1637414. Epub 2019 Jul 8. Expert Opin Drug Discov. 2019. PMID: 31284790 No abstract available.
Drugging cancer genomes.
Workman P, Al-Lazikani B. Workman P, et al. Among authors: al lazikani b. Nat Rev Drug Discov. 2013 Dec;12(12):889-90. doi: 10.1038/nrd4184. Nat Rev Drug Discov. 2013. PMID: 24287764 No abstract available.
64 results