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Year Number of Results
1951 1
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1955 1
1957 1
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1962 2
1964 1
1965 1
1966 1
1968 1
1969 1
1970 2
1975 1
1977 3
1981 1
1984 1
1996 2
1997 1
1998 1
1999 1
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2001 4
2003 1
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45 results

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Page 1
The discovery and structural basis of two distinct state-dependent inhibitors of BamA.
Sun D, Storek KM, Tegunov D, Yang Y, Arthur CP, Johnson M, Quinn JG, Liu W, Han G, Girgis HS, Alexander MK, Murchison AK, Shriver S, Tam C, Ijiri H, Inaba H, Sano T, Yanagida H, Nishikawa J, Heise CE, Fairbrother WJ, Tan MW, Skelton N, Sandoval W, Sellers BD, Ciferri C, Smith PA, Reid PC, Cunningham CN, Rutherford ST, Payandeh J. Sun D, et al. Among authors: alexander mk. Nat Commun. 2024 Oct 8;15(1):8718. doi: 10.1038/s41467-024-52512-1. Nat Commun. 2024. PMID: 39379361 Free PMC article.
Discovery of Inhibitors of the Lipopolysaccharide Transporter MsbA: From a Screening Hit to Potent Wild-Type Gram-Negative Activity.
Verma VA, Wang L, Labadie SS, Liang J, Sellers BD, Wang J, Dong L, Wang Q, Zhang S, Xu Z, Zhang Y, Niu Y, Wang X, Wai J, Koehler MFT, Hu H, Alexander MK, Nishiyama M, Miu A, Xu Y, Pang J, Katakam AK, Reichelt M, Austin CD, Ho H, Payandeh J, Koth CM. Verma VA, et al. Among authors: alexander mk. J Med Chem. 2022 Mar 10;65(5):4085-4120. doi: 10.1021/acs.jmedchem.1c01909. Epub 2022 Feb 20. J Med Chem. 2022. PMID: 35184554
Counting chromosomes: not as easy as 1, 2, 3.
Alexander MK, Panning B. Alexander MK, et al. Curr Biol. 2005 Oct 25;15(20):R834-6. doi: 10.1016/j.cub.2005.10.002. Curr Biol. 2005. PMID: 16243022 Free article. Review.
Disrupting Gram-Negative Bacterial Outer Membrane Biosynthesis through Inhibition of the Lipopolysaccharide Transporter MsbA.
Alexander MK, Miu A, Oh A, Reichelt M, Ho H, Chalouni C, Labadie S, Wang L, Liang J, Nickerson NN, Hu H, Yu L, Du M, Yan D, Park S, Kim J, Xu M, Sellers BD, Purkey HE, Skelton NJ, Koehler MFT, Payandeh J, Verma V, Xu Y, Koth CM, Nishiyama M. Alexander MK, et al. Antimicrob Agents Chemother. 2018 Oct 24;62(11):e01142-18. doi: 10.1128/AAC.01142-18. Print 2018 Nov. Antimicrob Agents Chemother. 2018. PMID: 30104274 Free PMC article.
Structural basis for dual-mode inhibition of the ABC transporter MsbA.
Ho H, Miu A, Alexander MK, Garcia NK, Oh A, Zilberleyb I, Reichelt M, Austin CD, Tam C, Shriver S, Hu H, Labadie SS, Liang J, Wang L, Wang J, Lu Y, Purkey HE, Quinn J, Franke Y, Clark K, Beresini MH, Tan MW, Sellers BD, Maurer T, Koehler MFT, Wecksler AT, Kiefer JR, Verma V, Xu Y, Nishiyama M, Payandeh J, Koth CM. Ho H, et al. Among authors: alexander mk. Nature. 2018 May;557(7704):196-201. doi: 10.1038/s41586-018-0083-5. Epub 2018 May 2. Nature. 2018. PMID: 29720648
45 results