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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 2
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2003 2
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2008 1
2009 3
2010 6
2011 5
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2013 2
2014 6
2015 3
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71 results

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Page 1
LncRNA-ANAPC2 and lncRNA-NEFM positively regulates the inflammatory response via the miR-451/npr2/ hdac8 axis in grass carp.
Pang Y, Li L, Yang Y, Shen Y, Xu X, Li J. Pang Y, et al. Fish Shellfish Immunol. 2022 Sep;128:1-6. doi: 10.1016/j.fsi.2022.07.014. Epub 2022 Jul 16. Fish Shellfish Immunol. 2022. PMID: 35843524
In the present study, miR-451 was highly expressed in Aeromonas hydrophila induced CIK cells, opposite to lncRNA-ANAPC2 and lncRNA-NEFM expression. Furthermore, we found that miR-451 interacted with lncRNA-ANAPC2 and lncRNA-NEFM, also targeted the 3' UTR of npr2 and …
In the present study, miR-451 was highly expressed in Aeromonas hydrophila induced CIK cells, opposite to lncRNA-ANAPC2 and lncRNA-NE …
Host-mediated ubiquitination of a mycobacterial protein suppresses immunity.
Wang L, Wu J, Li J, Yang H, Tang T, Liang H, Zuo M, Wang J, Liu H, Liu F, Chen J, Liu Z, Wang Y, Peng C, Wu X, Zheng R, Huang X, Ran Y, Rao Z, Ge B. Wang L, et al. Nature. 2020 Jan;577(7792):682-688. doi: 10.1038/s41586-019-1915-7. Epub 2020 Jan 15. Nature. 2020. PMID: 31942069
Here we report that the host E3 ubiquitin ligase ANAPC2-a core subunit of the anaphase-promoting complex/cyclosome-interacts with the mycobacterial protein Rv0222 and promotes the attachment of lysine-11-linked ubiquitin chains to lysine …
Here we report that the host E3 ubiquitin ligase ANAPC2-a core subunit of the anaphase-promoting complex/ …
APC/C is essential for hematopoiesis and impaired in aplastic anemia.
Wang J, Yin MZ, Zhao KW, Ke F, Jin WJ, Guo XL, Liu TH, Liu XY, Gu H, Yu XM, Li Z, Mu LL, Hong DL, Chen J, Chen GQ. Wang J, et al. Oncotarget. 2017 Jun 28;8(38):63360-63369. doi: 10.18632/oncotarget.18808. eCollection 2017 Sep 8. Oncotarget. 2017. PMID: 28968996 Free PMC article.
Anaphase promoting complex/cyclosome (APC/C) is essential for cell cycle progression. Recently, its non-mitotic functions were also reported but less studied in several tissues including hematopoietic cells. Here, we developed an inducible Anapc2 …
Anaphase promoting complex/cyclosome (APC/C) is essential for cell cycle progression. Recently, its non-mitotic …
Combination of artesunate and WNT974 induces KRAS protein degradation by upregulating E3 ligase ANACP2 and β-TrCP in the ubiquitin-proteasome pathway.
Gong RH, Chen M, Huang C, Wong HLX, Kwan HY, Bian Z. Gong RH, et al. Cell Commun Signal. 2022 Mar 19;20(1):34. doi: 10.1186/s12964-022-00834-2. Cell Commun Signal. 2022. PMID: 35305671 Free PMC article.
RT-PCR was utilized for the mRNA levels of KRAS, CUL7, ANAPC2, UBE2M, RNF123, SYVN1, or beta-TrCP. Western blot assay was utilized for the protein levels of NRAS, HRAS, KRAS, ANAPC2, beta-TrCP, GSK-3beta, p-Akt (Ser473), t-Akt, p-PI3K (Tyr458), t-PI3K, p-mTOR (Ser24 …
RT-PCR was utilized for the mRNA levels of KRAS, CUL7, ANAPC2, UBE2M, RNF123, SYVN1, or beta-TrCP. Western blot assay was utilized fo …
Cryo-EM structures of apo-APC/C and APC/CCDH1:EMI1 complexes provide insights into APC/C regulation.
Höfler A, Yu J, Yang J, Zhang Z, Chang L, McLaughlin SH, Grime GW, Garman EF, Boland A, Barford D. Höfler A, et al. Nat Commun. 2024 Nov 21;15(1):10074. doi: 10.1038/s41467-024-54398-5. Nat Commun. 2024. PMID: 39567505 Free PMC article.
APC/C is a multi-subunit complex that functions as a master regulator of cell division. It controls progression through the cell cycle by timely marking mitotic cyclins and other cell cycle regulatory proteins for degradation. ...We also identify a zinc-binding module in …
APC/C is a multi-subunit complex that functions as a master regulator of cell division. It controls progression through the cell cycl …
Systems genetics analysis of human body fat distribution genes identifies Wnt signaling and mitochondrial activity in adipocytes.
Reed JN, Huang J, Li Y, Ma L, Banka D, Wabitsch M, Wang T, Ding W, Björkegren JLM, Civelek M. Reed JN, et al. bioRxiv [Preprint]. 2023 Sep 6:2023.09.06.556534. doi: 10.1101/2023.09.06.556534. bioRxiv. 2023. Update in: Life Sci Alliance. 2024 May 3;7(7):e202402603. doi: 10.26508/lsa.202402603. PMID: 37732278 Free PMC article. Updated. Preprint.
We selected seven genes whose expression is highly correlated with WHRadjBMI to further study their effects on adipogenesis/Wnt signaling (ANAPC2, PSME3, RSPO1, TYRO3) or mitochondrial function (C1QTNF3, MIGA1, PSME3, UBR1).Adipogenesis was inhibited in cells overexpressin …
We selected seven genes whose expression is highly correlated with WHRadjBMI to further study their effects on adipogenesis/Wnt signaling ( …
Post translational modifications in tuberculosis: ubiquitination paradox.
Shariq M, Quadir N, Sheikh JA, Singh AK, Bishai WR, Ehtesham NZ, Hasnain SE. Shariq M, et al. Autophagy. 2021 Mar;17(3):814-817. doi: 10.1080/15548627.2020.1850009. Epub 2020 Nov 24. Autophagy. 2021. PMID: 33190592 Free PMC article. Review.
In the current article, we discuss the co-option of the ubiquitin pathway by the M. tb virulence effectors.Abbreviations: ANAPC2: anaphase promoting complex subunit 2; IL: interleukin; Lys: lysine (K); MAPK: mitogen-activated protein kinase; MAP3K7/TAK …
In the current article, we discuss the co-option of the ubiquitin pathway by the M. tb virulence effectors.Abbreviations: ANAPC2: …
Identifying fenofibrate responsive CpG sites.
Cantor R, Navarro L, Pan C. Cantor R, et al. BMC Proc. 2018 Sep 17;12(Suppl 9):43. doi: 10.1186/s12919-018-0148-3. eCollection 2018. BMC Proc. 2018. PMID: 30275892 Free PMC article.

Combined, these results identify methylation sites within the KIAA1804 and ANAPC2 genes. Each gene also has a highly significant methylation quantitative trait locus (meQTL) (KIAA1804: p < 1e-200; ANAPC2: p < 3e-248), indicating that methylation levels at thes

…
Combined, these results identify methylation sites within the KIAA1804 and ANAPC2 genes. Each gene also has a highly significant meth …
Multi-CpG linear regression models to accurately predict paclitaxel and docetaxel activity in cancer cell lines.
Bacolod MD, Fisher PB, Barany F. Bacolod MD, et al. Adv Cancer Res. 2023;158:233-292. doi: 10.1016/bs.acr.2022.12.005. Epub 2022 Dec 29. Adv Cancer Res. 2023. PMID: 36990534 Review.
Indeed, many of the genes represented in PTX or DTX CpG-based models have functionalities related to apoptosis (e.g., ACIN1, TP73, TNFRSF10B, DNASE1, DFFB, CREB1, BNIP3), and mitosis/microtubules (e.g., MAD1L1, ANAPC2, EML4, PARP3, CCT6A, JAKMIP1). Also represented are gen …
Indeed, many of the genes represented in PTX or DTX CpG-based models have functionalities related to apoptosis (e.g., ACIN1, TP73, TNFRSF10B …
LINKIN-associated proteins necessary for tissue integrity during collective cell migration.
Tan CH, Cheng KW, Park H, Chou TF, Sternberg PW. Tan CH, et al. bioRxiv [Preprint]. 2023 Aug 4:2023.02.08.527750. doi: 10.1101/2023.02.08.527750. bioRxiv. 2023. PMID: 36798316 Free PMC article. Preprint.
Loss-of-function analysis of their C. elegans orthologs found that three of the interactors - ATP9A/tat-5, NME1/ndk-1, and ANAPC2/apc-2 - displayed migratory detachment phenotypes similar to that of lnkn-1. Taken together with the other genes whose reduction-of-function ph …
Loss-of-function analysis of their C. elegans orthologs found that three of the interactors - ATP9A/tat-5, NME1/ndk-1, and ANAPC2/apc …
71 results