Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
2000 1
2002 1
2003 1
2005 1
2006 1
2010 3
2011 2
2012 2
2013 2
2014 3
2015 4
2016 2
2018 2
2019 1
2020 3
2021 3
2022 1
2023 4
2024 4
2025 1

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

40 results

Results by year

Filters applied: . Clear all
Page 1
Lactate regulates cell cycle by remodelling the anaphase promoting complex.
Liu W, Wang Y, Bozi LHM, Fischer PD, Jedrychowski MP, Xiao H, Wu T, Darabedian N, He X, Mills EL, Burger N, Shin S, Reddy A, Sprenger HG, Tran N, Winther S, Hinshaw SM, Shen J, Seo HS, Song K, Xu AZ, Sebastian L, Zhao JJ, Dhe-Paganon S, Che J, Gygi SP, Arthanari H, Chouchani ET. Liu W, et al. Nature. 2023 Apr;616(7958):790-797. doi: 10.1038/s41586-023-05939-3. Epub 2023 Mar 15. Nature. 2023. PMID: 36921622 Free PMC article.
From these data, we identify a mechanism of cell cycle regulation whereby accumulated lactate remodels the anaphase promoting complex (APC/C). Remodelling of APC/C in this way is caused by direct inhibition of the SUMO protease SENP1 by lactate. ...SENP1 inhibition …
From these data, we identify a mechanism of cell cycle regulation whereby accumulated lactate remodels the anaphase promoting …
Bidirectional relationship between olfaction and Parkinson's disease.
Kim JJ, Bandres-Ciga S, Heilbron K; 23andMe Research Team; Blauwendraat C, Noyce AJ. Kim JJ, et al. NPJ Parkinsons Dis. 2024 Dec 5;10(1):232. doi: 10.1038/s41531-024-00838-4. NPJ Parkinsons Dis. 2024. PMID: 39639040 Free PMC article.
Local Analysis of [co]Variant Association (LAVA) found negative correlations in four genetic loci near GBA1, ANAPC4, SNCA, and MAPT, indicating shared genetic liability only within a subset of prominent PD risk genes. ...
Local Analysis of [co]Variant Association (LAVA) found negative correlations in four genetic loci near GBA1, ANAPC4, SNCA, and MAPT, …
TRMT13 inhibits the growth of papillary thyroid cancer by targeting ANAPC4.
Liu L, Wang Y, Zou M, Chen S, Wu F, Li X. Liu L, et al. Acta Biochim Biophys Sin (Shanghai). 2024 Mar 1;56(9):1267-1277. doi: 10.3724/abbs.2024010. Acta Biochim Biophys Sin (Shanghai). 2024. PMID: 38425244 Free PMC article.
A nude mouse tumor model is used to evaluate the effects of TRMT13 and ANAPC4 on PTC tumorigenesis. TRMT13 expression is decreased in PTC tissues and cell lines and is positively correlated with that of ANAPC4. ...In the nude mouse xenograft model, both TRMT13 and …
A nude mouse tumor model is used to evaluate the effects of TRMT13 and ANAPC4 on PTC tumorigenesis. TRMT13 expression is decreased in …
Genetic overlap and causality between COVID-19 and multi-site chronic pain: the importance of immunity.
Chen Y, Liu P, Zhang Z, Ye Y, Yi S, Fan C, Zhao W, Liu J. Chen Y, et al. Front Immunol. 2024 Mar 18;15:1277720. doi: 10.3389/fimmu.2024.1277720. eCollection 2024. Front Immunol. 2024. PMID: 38633255 Free PMC article.
A total of 482 significant overlapped genes were detected from MAGMA and CPASSOC results. Additionally, the gene ANAPC4 was identified as a potential drug target for treating chronic pain (P=7.66E-05) in COVID-19 (P=8.23E-03). ...
A total of 482 significant overlapped genes were detected from MAGMA and CPASSOC results. Additionally, the gene ANAPC4 was identifie …
Cannabinol Regulates the Expression of Cell Cycle-Associated Genes in Motor Neuron-like NSC-34: A Transcriptomic Analysis.
Trainito A, Gugliandolo A, Chiricosta L, Salamone S, Pollastro F, Mazzon E, Lui M. Trainito A, et al. Biomedicines. 2024 Jun 17;12(6):1340. doi: 10.3390/biomedicines12061340. Biomedicines. 2024. PMID: 38927547 Free PMC article.
Ccne2, Cdk2, Cdk7, Anapc11, Anapc10, Cdc23, Cdc16, Anapc4, Cdc27, Stag1, Smc3, Smc1a, Nipbl, Pds5a, Pds5b, and Wapl genes, renowned for their role as cell cycle progression activators, were instead upregulated. ...
Ccne2, Cdk2, Cdk7, Anapc11, Anapc10, Cdc23, Cdc16, Anapc4, Cdc27, Stag1, Smc3, Smc1a, Nipbl, Pds5a, Pds5b, and Wapl genes, renowned f …
Bidirectional relationship between olfaction and Parkinson's disease.
Kim JJ, Bandres-Ciga S, Heilbron K; 23andMe Research Team; Blauwendraat C, Noyce AJ. Kim JJ, et al. medRxiv [Preprint]. 2023 Oct 19:2023.10.18.23297218. doi: 10.1101/2023.10.18.23297218. medRxiv. 2023. Update in: NPJ Parkinsons Dis. 2024 Dec 5;10(1):232. doi: 10.1038/s41531-024-00838-4. PMID: 37905151 Free PMC article. Updated. Preprint.
LAVA found negative correlations in four genetic loci near GBA1, ANAPC4, SNCA, and MAPT. Using Mendelian randomization we found evidence for strong causal relationship between PD and liability towards poorer sense of smell, but weaker evidence for the reverse direction. .. …
LAVA found negative correlations in four genetic loci near GBA1, ANAPC4, SNCA, and MAPT. Using Mendelian randomization we found evide …
Concurrent mutations associated with trastuzumab-resistance revealed by single cell sequencing.
Gao Y, Wu N, Wang S, Yang X, Wang X, Xu B. Gao Y, et al. Breast Cancer Res Treat. 2021 Jun;187(3):613-624. doi: 10.1007/s10549-021-06237-0. Epub 2021 Apr 27. Breast Cancer Res Treat. 2021. PMID: 33905021
By validation, we found that concurrent mutations (AIFM1 P548L and IL1RAPL2 S546C in SK-BR-3 cells, MFSD11 L242I and ANAPC4 E16K in BT-474 cells) led to a decrease of trastuzumab sensitivity. CONCLUSION: Taken together, our study revealed a common pathway level trastuzumab …
By validation, we found that concurrent mutations (AIFM1 P548L and IL1RAPL2 S546C in SK-BR-3 cells, MFSD11 L242I and ANAPC4 E16K in B …
Identification of Key Candidate Genes for Beak Length Phenotype by Whole-Genome Resequencing in Geese.
Huang J, Wang C, Ouyang J, Tang H, Zheng S, Xiong Y, Gao Y, Wu Y, Wang L, Yan X, Chen H. Huang J, et al. Front Vet Sci. 2022 Mar 15;9:847481. doi: 10.3389/fvets.2022.847481. eCollection 2022. Front Vet Sci. 2022. PMID: 35372529 Free PMC article.
The results indicated that 57 SNPs reached genome-wide significance levels for the beak length trait and were assigned to seven genes, including TAPT1, DHX15, CCDC149, LGI2, SEPSECS, ANAPC4, and Slc34a2. The different genotypes of the most significant SNP (top SNP), which …
The results indicated that 57 SNPs reached genome-wide significance levels for the beak length trait and were assigned to seven genes, inclu …
Development and Validation of a Prognosis-Prediction Signature for Patients with Lung Adenocarcinoma Based on 11 Telomere-Related Genes.
Liu J, Sha S, Wang J, Gu X, Du M, Lu X. Liu J, et al. Front Biosci (Landmark Ed). 2023 Oct 20;28(10):254. doi: 10.31083/j.fbl2810254. Front Biosci (Landmark Ed). 2023. PMID: 37919072 Free article.
Using cluster consistency analysis and regression with the least absolute shrinkage and selection operator, we developed a telomere-related gene risk signature (TMGsig) based on 11 overall survival-related genes (RBBP8, PLK1, DSG2, HOXA7, ANAPC4, CSNK1E, SYAP1, ALDOA, PHF1 …
Using cluster consistency analysis and regression with the least absolute shrinkage and selection operator, we developed a telomere-related …
Integrating GWAS and eQTL to predict genes and pathways for non-syndromic cleft lip with or without palate.
Yang J, Yu X, Zhu G, Wang R, Lou S, Zhu W, Fu C, Liu J, Fan L, Li D, Shao Q, Ma L, Wang L, Wang Z, Pan Y. Yang J, et al. Oral Dis. 2021 Oct;27(7):1747-1754. doi: 10.1111/odi.13699. Epub 2020 Dec 14. Oral Dis. 2021. PMID: 33128317
PPI network analysis highlighted that these genes involved in ubiquitin-mediated proteolysis (KCTD7, ASB1, UBOX5, ANAPC4) and DNA synthesis (XRCC3, RFC3, KAT5, RHNO1) were associated with the risk of NSCL/P. ...
PPI network analysis highlighted that these genes involved in ubiquitin-mediated proteolysis (KCTD7, ASB1, UBOX5, ANAPC4) and DNA syn …
40 results