Appel SH[au] - Search Results

Year	Number of Results
1958	1
1959	1
1964	3
1965	5
1966	2
1967	2
1968	6
1969	2
1970	6
1971	5
1972	2
1973	9
1974	10
1975	9
1976	12
1977	6
1978	9
1979	4
1980	3
1981	5
1982	4
1983	2
1984	3
1985	8
1986	3
1987	2
1988	8
1989	12
1990	6
1991	8
1992	11
1993	10
1994	10
1995	14
1996	9
1997	9
1998	7
1999	9
2000	9
2001	7
2002	4
2003	8
2004	10
2005	7
2006	11
2007	3
2008	5
2009	7
2010	7
2011	7
2012	7
2013	5
2014	3
2015	3
2016	4
2017	7
2018	8
2019	6
2020	6
2021	2

1

Immune dysregulation in amyotrophic lateral sclerosis: mechanisms and emerging therapies.

Beers DR, Appel SH. Beers DR, et al. Among authors: appel sh. Lancet Neurol. 2019 Feb;18(2):211-220. doi: 10.1016/S1474-4422(18)30394-6. Lancet Neurol. 2019. PMID: 30663610 Review.

2

Neuroinflammatory mechanisms in amyotrophic lateral sclerosis pathogenesis.

Thonhoff JR, Simpson EP, Appel SH. Thonhoff JR, et al. Among authors: appel sh. Curr Opin Neurol. 2018 Oct;31(5):635-639. doi: 10.1097/WCO.0000000000000599. Curr Opin Neurol. 2018. PMID: 30048339 Review.

3

TDP-43 activates microglia through NF-κB and NLRP3 inflammasome.

Zhao W, Beers DR, Bell S, Wang J, Wen S, Baloh RH, Appel SH. Zhao W, et al. Among authors: appel sh. Exp Neurol. 2015 Nov;273:24-35. doi: 10.1016/j.expneurol.2015.07.019. Epub 2015 Jul 26. Exp Neurol. 2015. PMID: 26222336

4

An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study.

Miller TM, Pestronk A, David W, Rothstein J, Simpson E, Appel SH, Andres PL, Mahoney K, Allred P, Alexander K, Ostrow LW, Schoenfeld D, Macklin EA, Norris DA, Manousakis G, Crisp M, Smith R, Bennett CF, Bishop KM, Cudkowicz ME. Miller TM, et al. Among authors: appel sh. Lancet Neurol. 2013 May;12(5):435-42. doi: 10.1016/S1474-4422(13)70061-9. Epub 2013 Mar 29. Lancet Neurol. 2013. PMID: 23541756 Free PMC article. Clinical Trial.

5

ALS patients' regulatory T lymphocytes are dysfunctional, and correlate with disease progression rate and severity.

Beers DR, Zhao W, Wang J, Zhang X, Wen S, Neal D, Thonhoff JR, Alsuliman AS, Shpall EJ, Rezvani K, Appel SH. Beers DR, et al. Among authors: appel sh. JCI Insight. 2017 Mar 9;2(5):e89530. doi: 10.1172/jci.insight.89530. JCI Insight. 2017. PMID: 28289705 Free PMC article.

6

Expanded autologous regulatory T-lymphocyte infusions in ALS: A phase I, first-in-human study.

Thonhoff JR, Beers DR, Zhao W, Pleitez M, Simpson EP, Berry JD, Cudkowicz ME, Appel SH. Thonhoff JR, et al. Among authors: appel sh. Neurol Neuroimmunol Neuroinflamm. 2018 May 18;5(4):e465. doi: 10.1212/NXI.0000000000000465. eCollection 2018 Jul. Neurol Neuroimmunol Neuroinflamm. 2018. PMID: 29845093 Free PMC article.

7

Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis.

Beers DR, Henkel JS, Zhao W, Wang J, Huang A, Wen S, Liao B, Appel SH. Beers DR, et al. Among authors: appel sh. Brain. 2011 May;134(Pt 5):1293-314. doi: 10.1093/brain/awr074. Brain. 2011. PMID: 21596768 Free PMC article.

8

The immune system continues to knock at the ALS door.

Staff NP, Appel SH. Staff NP, et al. Among authors: appel sh. Neuromuscul Disord. 2016 Jun;26(6):335-6. doi: 10.1016/j.nmd.2016.04.010. Epub 2016 Apr 19. Neuromuscul Disord. 2016. PMID: 27133660 No abstract available.

9

Increased activation ability of monocytes from ALS patients.

Du Y, Zhao W, Thonhoff JR, Wang J, Wen S, Appel SH. Du Y, et al. Among authors: appel sh. Exp Neurol. 2020 Jun;328:113259. doi: 10.1016/j.expneurol.2020.113259. Epub 2020 Feb 24. Exp Neurol. 2020. PMID: 32105709

10

The Role of Regulatory T Lymphocytes in Amyotrophic Lateral Sclerosis.

Beers DR, Zhao W, Appel SH. Beers DR, et al. Among authors: appel sh. JAMA Neurol. 2018 Jun 1;75(6):656-658. doi: 10.1001/jamaneurol.2018.0043. JAMA Neurol. 2018. PMID: 29507936 No abstract available.

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