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Year Number of Results
2012 2
2015 1
2016 1
2018 2
2021 1
2022 2
2023 2
2024 0

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11 results

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Page 1
Activation of Tumor-Cell STING Primes NK-Cell Therapy.
Knelson EH, Ivanova EV, Tarannum M, Campisi M, Lizotte PH, Booker MA, Ozgenc I, Noureddine M, Meisenheimer B, Chen M, Piel B, Spicer N, Obua B, Messier CM, Shannon E, Mahadevan NR, Tani T, Schol PJ, Lee-Hassett AM, Zlota A, Vo HV, Ha M, Bertram AA, Han S, Thai TC, Gustafson CE, Venugopal K, Haggerty TJ, Albertson TP, Hartley AV, Eser PO, Li ZH, Cañadas I, Vivero M, De Rienzo A, Richards WG, Abu-Yousif AO, Appleman VA, Gregory RC, Parent A, Lineberry N, Smith EL, Jänne PA, Miret JJ, Tolstorukov MY, Romee R, Paweletz CP, Bueno R, Barbie DA. Knelson EH, et al. Among authors: appleman va. Cancer Immunol Res. 2022 Aug 3;10(8):947-961. doi: 10.1158/2326-6066.CIR-22-0017. Cancer Immunol Res. 2022. PMID: 35678717 Free PMC article.
Investigation of the enhanced antitumour potency of STING agonist after conjugation to polymer nanoparticles.
Dosta P, Cryer AM, Dion MZ, Shiraishi T, Langston SP, Lok D, Wang J, Harrison S, Hatten T, Ganno ML, Appleman VA, Taboada GM, Puigmal N, Ferber S, Kalash S, Prado M, Rodríguez AL, Kamoun WS, Abu-Yousif AO, Artzi N. Dosta P, et al. Among authors: appleman va. Nat Nanotechnol. 2023 Nov;18(11):1351-1363. doi: 10.1038/s41565-023-01447-7. Epub 2023 Jul 13. Nat Nanotechnol. 2023. PMID: 37443252
TAK-676: A Novel Stimulator of Interferon Genes (STING) Agonist Promoting Durable IFN-dependent Antitumor Immunity in Preclinical Studies.
Carideo Cunniff E, Sato Y, Mai D, Appleman VA, Iwasaki S, Kolev V, Matsuda A, Shi J, Mochizuki M, Yoshikawa M, Huang J, Shen L, Haridas S, Shinde V, Gemski C, Roberts ER, Ghasemi O, Bazzazi H, Menon S, Traore T, Shi P, Thelen TD, Conlon J, Abu-Yousif AO, Arendt C, Shaw MH, Okaniwa M. Carideo Cunniff E, et al. Among authors: appleman va. Cancer Res Commun. 2022 Jun 23;2(6):489-502. doi: 10.1158/2767-9764.CRC-21-0161. eCollection 2022 Jun. Cancer Res Commun. 2022. PMID: 36923556 Free PMC article.
A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine.
Jun HJ, Appleman VA, Wu HJ, Rose CM, Pineda JJ, Yeo AT, Delcuze B, Lee C, Gyuris A, Zhu H, Woolfenden S, Bronisz A, Nakano I, Chiocca EA, Bronson RT, Ligon KL, Sarkaria JN, Gygi SP, Michor F, Mitchison TJ, Charest A. Jun HJ, et al. Among authors: appleman va. Nat Commun. 2018 Aug 6;9(1):3116. doi: 10.1038/s41467-018-05036-4. Nat Commun. 2018. PMID: 30082792 Free PMC article.
The activity of Gli transcription factors is essential for Kras-induced pancreatic tumorigenesis.
Rajurkar M, De Jesus-Monge WE, Driscoll DR, Appleman VA, Huang H, Cotton JL, Klimstra DS, Zhu LJ, Simin K, Xu L, McMahon AP, Lewis BC, Mao J. Rajurkar M, et al. Among authors: appleman va. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):E1038-47. doi: 10.1073/pnas.1114168109. Epub 2012 Apr 9. Proc Natl Acad Sci U S A. 2012. PMID: 22493246 Free PMC article.
Activation of WNT/β-Catenin Signaling Enhances Pancreatic Cancer Development and the Malignant Potential Via Up-regulation of Cyr61.
Sano M, Driscoll DR, DeJesus-Monge WE, Quattrochi B, Appleman VA, Ou J, Zhu LJ, Yoshida N, Yamazaki S, Takayama T, Sugitani M, Nemoto N, Klimstra DS, Lewis BC. Sano M, et al. Among authors: appleman va. Neoplasia. 2016 Dec;18(12):785-794. doi: 10.1016/j.neo.2016.11.004. Epub 2016 Nov 25. Neoplasia. 2016. PMID: 27889647 Free PMC article.
11 results