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The following term was not found in PubMed: Tootabi
Page 1
Did you mean aram toolabi (1 results)?
T cell activation.
Smith-Garvin JE, Koretzky GA, Jordan MS. Smith-Garvin JE, et al. Annu Rev Immunol. 2009;27:591-619. doi: 10.1146/annurev.immunol.021908.132706. Annu Rev Immunol. 2009. PMID: 19132916 Free PMC article. Review.
This review continues with a description of the current state of our understanding of TCR signaling, as well as a summary of recent findings examining other key aspects of T cell activation, including cross talk between the TCR and integrins, the role of costimulatory mole …
This review continues with a description of the current state of our understanding of TCR signaling, as well as a summary of recent findings …
Role of platelets and platelet receptors in cancer metastasis.
Schlesinger M. Schlesinger M. J Hematol Oncol. 2018 Oct 11;11(1):125. doi: 10.1186/s13045-018-0669-2. J Hematol Oncol. 2018. PMID: 30305116 Free PMC article. Review.
This review provides a synopsis on the current literature on platelet-mediated effects in cancer metastasis and particularly focuses on platelet adhesion receptors and their role in metastasis. Immunoreceptor tyrosine-based activation motif (ITA …
This review provides a synopsis on the current literature on platelet-mediated effects in cancer metastasis and particularly focuses on plat …
Calibration of CAR activation potential directs alternative T cell fates and therapeutic potency.
Feucht J, Sun J, Eyquem J, Ho YJ, Zhao Z, Leibold J, Dobrin A, Cabriolu A, Hamieh M, Sadelain M. Feucht J, et al. Nat Med. 2019 Jan;25(1):82-88. doi: 10.1038/s41591-018-0290-5. Epub 2018 Dec 17. Nat Med. 2019. PMID: 30559421 Free PMC article.
Thus, we hypothesized that calibrating the activation potential of CD28-based CARs would differentially reprogram T cell function and differentiation. Here, we show that CARs encoding a single immunoreceptor tyrosine-based activation motif
Thus, we hypothesized that calibrating the activation potential of CD28-based CARs would differentially reprogram T cell function and …
Platelet ITAM signaling.
Bergmeier W, Stefanini L. Bergmeier W, et al. Curr Opin Hematol. 2013 Sep;20(5):445-50. doi: 10.1097/MOH.0b013e3283642267. Curr Opin Hematol. 2013. PMID: 23921514 Review.
PURPOSE OF REVIEW: G protein-coupled receptors (GPCRs) like PAR1/4 and P2Y12 have long been known for their critical role in hemostasis. In contrast, deficiency in the immunoreceptor tyrosine-based activation motif (ITAM)-coupled receptors glyco …
PURPOSE OF REVIEW: G protein-coupled receptors (GPCRs) like PAR1/4 and P2Y12 have long been known for their critical role in hemostasis. In …
The TREM-1/DAP12 pathway.
Tessarz AS, Cerwenka A. Tessarz AS, et al. Immunol Lett. 2008 Mar 15;116(2):111-6. doi: 10.1016/j.imlet.2007.11.021. Epub 2007 Dec 26. Immunol Lett. 2008. PMID: 18192027 Review.
DNAX activation protein of 12kDa (DAP12) is an immunoreceptor tyrosine-based activation motif (ITAM)-bearing adapter, which couples to multiple receptors expressed on natural killer (NK) cells, monocytes, and neutrophils. ...
DNAX activation protein of 12kDa (DAP12) is an immunoreceptor tyrosine-based activation motif (ITA …
RBP-J and ITAM crosstalk.
Zhao B. Zhao B. Oncotarget. 2015 Nov 3;6(34):35135-6. doi: 10.18632/oncotarget.6034. Oncotarget. 2015. PMID: 26459387 Free PMC article. No abstract available.
Molecular mechanisms of immunoreceptors in platelets.
Kuriri FA, O'Malley CJ, Jackson DE. Kuriri FA, et al. Thromb Res. 2019 Apr;176:108-114. doi: 10.1016/j.thromres.2019.01.019. Epub 2019 Feb 10. Thromb Res. 2019. PMID: 30802692 Review.
Naturally, bioactive mediators are released from endothelial cells to prevent and control platelet activation. However, when the vascular endothelium is ruptured, the local concentration of nitric oxide and prostaglandin is diminished and receptors containing a sequence of …
Naturally, bioactive mediators are released from endothelial cells to prevent and control platelet activation. However, when the vasc …
Siglec functions of microglia.
Linnartz-Gerlach B, Kopatz J, Neumann H. Linnartz-Gerlach B, et al. Glycobiology. 2014 Sep;24(9):794-9. doi: 10.1093/glycob/cwu044. Epub 2014 May 15. Glycobiology. 2014. PMID: 24833613 Review.
Therefore, microglia need recognition receptors that lead to either the activation or the inhibition of the immune response pathways. Most Siglecs contain an immunoreceptor tyrosine based inhibition motif and its signaling leads to the terminati …
Therefore, microglia need recognition receptors that lead to either the activation or the inhibition of the immune response pathways. …
Hemostasis without clot formation: how platelets guard the vasculature in inflammation, infection, and malignancy.
Kaiser R, Escaig R, Nicolai L. Kaiser R, et al. Blood. 2023 Oct 26;142(17):1413-1425. doi: 10.1182/blood.2023020535. Blood. 2023. PMID: 37683182 Free article. Review.
Platelets are key vascular effectors in hemostasis, with activation signals leading to fast recruitment, aggregation, and clot formation. The canonical process of hemostasis is well-characterized and shares many similarities with pathological thrombus formation. ...Further …
Platelets are key vascular effectors in hemostasis, with activation signals leading to fast recruitment, aggregation, and clot format …
Recognition of Mycobacterial Lipids by Immune Receptors.
Ishikawa E, Mori D, Yamasaki S. Ishikawa E, et al. Trends Immunol. 2017 Jan;38(1):66-76. doi: 10.1016/j.it.2016.10.009. Epub 2016 Nov 23. Trends Immunol. 2017. PMID: 27889398 Review.
Here we review and summarize our current state of knowledge regarding innate immune receptors for mycobacteria, focusing particularly on immunoreceptor tyrosine-based activation motif (ITAM)-coupled C-type lectin receptors (CLRs), which have bee …
Here we review and summarize our current state of knowledge regarding innate immune receptors for mycobacteria, focusing particularly on …
1,613 results