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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 2
1981 3
1982 7
1983 3
1984 7
1985 1
1986 2
1987 3
1988 2
1989 1
1990 6
1991 3
1992 4
1993 3
1994 2
1995 2
1996 5
1997 5
1998 2
1999 5
2000 3
2001 5
2002 4
2003 4
2004 2
2005 4
2006 3
2007 1
2008 2
2009 5
2010 4
2011 3
2012 2
2013 4
2014 5
2015 6
2016 11
2017 8
2018 13
2019 7
2020 4
2021 3
2022 5
2023 6
2024 4

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175 results

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Page 1
Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington's disease.
O'Reilly D, Belgrad J, Ferguson C, Summers A, Sapp E, McHugh C, Mathews E, Boudi A, Buchwald J, Ly S, Moreno D, Furgal R, Luu E, Kennedy Z, Hariharan V, Monopoli K, Yang XW, Carroll J, DiFiglia M, Aronin N, Khvorova A. O'Reilly D, et al. Among authors: aronin n. Mol Ther. 2023 Jun 7;31(6):1661-1674. doi: 10.1016/j.ymthe.2023.05.006. Epub 2023 May 12. Mol Ther. 2023. PMID: 37177784 Free PMC article.
A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system.
Alterman JF, Godinho BMDC, Hassler MR, Ferguson CM, Echeverria D, Sapp E, Haraszti RA, Coles AH, Conroy F, Miller R, Roux L, Yan P, Knox EG, Turanov AA, King RM, Gernoux G, Mueller C, Gray-Edwards HL, Moser RP, Bishop NC, Jaber SM, Gounis MJ, Sena-Esteves M, Pai AA, DiFiglia M, Aronin N, Khvorova A. Alterman JF, et al. Among authors: aronin n. Nat Biotechnol. 2019 Aug;37(8):884-894. doi: 10.1038/s41587-019-0205-0. Epub 2019 Aug 2. Nat Biotechnol. 2019. PMID: 31375812 Free PMC article.
Chemical engineering of therapeutic siRNAs for allele-specific gene silencing in Huntington's disease models.
Conroy F, Miller R, Alterman JF, Hassler MR, Echeverria D, Godinho BMDC, Knox EG, Sapp E, Sousa J, Yamada K, Mahmood F, Boudi A, Kegel-Gleason K, DiFiglia M, Aronin N, Khvorova A, Pfister EL. Conroy F, et al. Among authors: aronin n. Nat Commun. 2022 Oct 3;13(1):5802. doi: 10.1038/s41467-022-33061-x. Nat Commun. 2022. PMID: 36192390 Free PMC article.
Huntington's Disease: Les Jeux Sont Faits?
Pfister EL, Aronin N. Pfister EL, et al. Among authors: aronin n. Trends Mol Med. 2020 Oct;26(10):889-890. doi: 10.1016/j.molmed.2020.08.004. Epub 2020 Sep 4. Trends Mol Med. 2020. PMID: 32893090
Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington's disease.
O'Reilly D, Belgrad J, Ferguson C, Summers A, Sapp E, McHugh C, Mathews E, Boudi A, Buchwald J, Ly S, Moreno D, Furgal R, Luu E, Kennedy Z, Hariharan V, Monopoli K, Yang XW, Carroll J, DiFiglia M, Aronin N, Khvorova A. O'Reilly D, et al. Among authors: aronin n. Mol Ther. 2023 Nov 1;31(11):3355-3356. doi: 10.1016/j.ymthe.2023.09.016. Epub 2023 Sep 25. Mol Ther. 2023. PMID: 37751745 Free article. No abstract available.
Target selectivity in mRNA silencing.
Aronin N. Aronin N. Gene Ther. 2006 Mar;13(6):509-16. doi: 10.1038/sj.gt.3302726. Gene Ther. 2006. PMID: 16520821 Free PMC article. Review.
175 results