Biocatalytic synthesis of oxadiazole thioethers and evaluation of their antitumor activity.
Neissari N, Shahedi M, Habibi Z, Yousefi M, Minai-Tehrani A, Yazdi Samadi F, Brask J, Bavandi H, Mohammadi M.
Neissari N, et al. Among authors: yazdi samadi f.
Org Biomol Chem. 2023 Jun 14;21(23):4846-4853. doi: 10.1039/d2ob02307e.
Org Biomol Chem. 2023.
PMID: 37249163
Novozym 435, the immobilized form of Candida antarctica lipase B (CALB), was found to efficiently catalyze the reaction. The products were evaluated for antitumor activities against two cancer cell lines, HT-29 (human colorectal cancer cell) and HepG2 (human liver cancer c …
Novozym 435, the immobilized form of Candida antarctica lipase B (CALB), was found to efficiently catalyze the reaction. The products …