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338 results

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Page 1
Showing results for B. andalusian
Your search for B. Andarzian retrieved no results
Frailty and Multimorbidity: A Systematic Review and Meta-analysis.
Vetrano DL, Palmer K, Marengoni A, Marzetti E, Lattanzio F, Roller-Wirnsberger R, Lopez Samaniego L, Rodríguez-Mañas L, Bernabei R, Onder G; Joint Action ADVANTAGE WP4 Group. Vetrano DL, et al. J Gerontol A Biol Sci Med Sci. 2019 Apr 23;74(5):659-666. doi: 10.1093/gerona/gly110. J Gerontol A Biol Sci Med Sci. 2019. PMID: 29726918
We reviewed the literature and provided pooled estimations of any evidence regarding (a) the coexistence of frailty and multimorbidity and (b) their association. METHODS: We searched PubMed and Web of Science for relevant articles up to September 2017. ...
We reviewed the literature and provided pooled estimations of any evidence regarding (a) the coexistence of frailty and multimorbidity and ( …
Long-term secondary prevention of cardiovascular disease with a Mediterranean diet and a low-fat diet (CORDIOPREV): a randomised controlled trial.
Delgado-Lista J, Alcala-Diaz JF, Torres-Peña JD, Quintana-Navarro GM, Fuentes F, Garcia-Rios A, Ortiz-Morales AM, Gonzalez-Requero AI, Perez-Caballero AI, Yubero-Serrano EM, Rangel-Zuñiga OA, Camargo A, Rodriguez-Cantalejo F, Lopez-Segura F, Badimon L, Ordovas JM, Perez-Jimenez F, Perez-Martinez P, Lopez-Miranda J; CORDIOPREV Investigators. Delgado-Lista J, et al. Lancet. 2022 May 14;399(10338):1876-1885. doi: 10.1016/S0140-6736(22)00122-2. Epub 2022 May 4. Lancet. 2022. PMID: 35525255 Clinical Trial.
Patients with established coronary heart disease (aged 20-75 years) were randomly assigned in a 1:1 ratio by the Andalusian School of Public Health to receive a Mediterranean diet or a low-fat diet intervention, with a follow-up of 7 years. ...
Patients with established coronary heart disease (aged 20-75 years) were randomly assigned in a 1:1 ratio by the Andalusian School of …
The trans-ancestral genomic architecture of glycemic traits.
Chen J, Spracklen CN, Marenne G, Varshney A, Corbin LJ, Luan J, Willems SM, Wu Y, Zhang X, Horikoshi M, Boutin TS, Mägi R, Waage J, Li-Gao R, Chan KHK, Yao J, Anasanti MD, Chu AY, Claringbould A, Heikkinen J, Hong J, Hottenga JJ, Huo S, Kaakinen MA, Louie T, März W, Moreno-Macias H, Ndungu A, Nelson SC, Nolte IM, North KE, Raulerson CK, Ray D, Rohde R, Rybin D, Schurmann C, Sim X, Southam L, Stewart ID, Wang CA, Wang Y, Wu P, Zhang W, Ahluwalia TS, Appel EVR, Bielak LF, Brody JA, Burtt NP, Cabrera CP, Cade BE, Chai JF, Chai X, Chang LC, Chen CH, Chen BH, Chitrala KN, Chiu YF, de Haan HG, Delgado GE, Demirkan A, Duan Q, Engmann J, Fatumo SA, Gayán J, Giulianini F, Gong JH, Gustafsson S, Hai Y, Hartwig FP, He J, Heianza Y, Huang T, Huerta-Chagoya A, Hwang MY, Jensen RA, Kawaguchi T, Kentistou KA, Kim YJ, Kleber ME, Kooner IK, Lai S, Lange LA, Langefeld CD, Lauzon M, Li M, Ligthart S, Liu J, Loh M, Long J, Lyssenko V, Mangino M, Marzi C, Montasser ME, Nag A, Nakatochi M, Noce D, Noordam R, Pistis G, Preuss M, Raffield L, Rasmussen-Torvik LJ, Rich SS, Robertson NR, Rueedi R, Ryan K, Sanna S, Saxena R, Schraut KE, Sennblad B, Setoh K, Smith AV, Sparsø T, Strawbridge RJ, Takeuchi F, Tan… See abstract for full author list ➔ Chen J, et al. Nat Genet. 2021 Jun;53(6):840-860. doi: 10.1038/s41588-021-00852-9. Epub 2021 May 31. Nat Genet. 2021. PMID: 34059833 Free PMC article.
The role of cellular senescence in neurodegenerative diseases.
Wang Y, Kuca K, You L, Nepovimova E, Heger Z, Valko M, Adam V, Wu Q, Jomova K. Wang Y, et al. Arch Toxicol. 2024 Aug;98(8):2393-2408. doi: 10.1007/s00204-024-03768-5. Epub 2024 May 15. Arch Toxicol. 2024. PMID: 38744709 Free PMC article. Review.
Selective clearance of senescent cells and SASP regulation by inhibiting p38/mitogen-activated protein kinase and nuclear factor kappa B signaling attenuate beta-amyloid load and prevent tau-protein tangle deposition, thereby improving cognitive performance in AD mouse mod …
Selective clearance of senescent cells and SASP regulation by inhibiting p38/mitogen-activated protein kinase and nuclear factor kappa B …
B Cells and Microbiota in Autoimmunity.
Botía-Sánchez M, Alarcón-Riquelme ME, Galicia G. Botía-Sánchez M, et al. Int J Mol Sci. 2021 May 3;22(9):4846. doi: 10.3390/ijms22094846. Int J Mol Sci. 2021. PMID: 34063669 Free PMC article. Review.
Trillions of microorganisms inhabit the mucosal membranes maintaining a symbiotic relationship with the host's immune system. B cells are key players in this relationship because activated and differentiated B cells produce secretory immunoglobulin A (sIgA), which b …
Trillions of microorganisms inhabit the mucosal membranes maintaining a symbiotic relationship with the host's immune system. B cells …
Mutations in the small nuclear RNA gene RNU2-2 cause a severe neurodevelopmental disorder with prominent epilepsy.
Greene D, De Wispelaere K, Lees J, Codina-Solà M, Jensson BO, Hales E, Katrinecz A, Nieto Molina E, Pascoal S, Pfundt R, Schot R, Sevilla Porras M, Sleutels F, Valenzuela I, Wijngaard R, Arroyo Carrera I, Atton G, Casas-Alba D, Donnelly D, Duat Rodríguez A, Fernández Garoz B, Foulds N, García-Navas Núñez D, González Alguacil E, Jarvis J, Kant SG, Madrigal Bajo I, Martinez-Monseny AF, McKee S, Ortiz Cabrera NV, Rodríguez-Revenga Bodi L, Sariego Jamardo A, Stefansson K, Sulem P, Suri M, Van Karnebeek C, Vasudevan P, Vega Pajares AI, Carracedo Á, Engelen M, Lapunzina P, Morgan NP, Morte B, Rump P, Stirrups K, Tizzano EF, Barakat TS, O'Donoghue M, Pérez-Jurado LA, Freson K, Mumford AD, Turro E. Greene D, et al. Nat Genet. 2025 Jun;57(6):1367-1373. doi: 10.1038/s41588-025-02159-5. Epub 2025 Apr 10. Nat Genet. 2025. PMID: 40210679 Free PMC article.
The Role of BANK1 in B Cell Signaling and Disease.
Gómez Hernández G, Morell M, Alarcón-Riquelme ME. Gómez Hernández G, et al. Cells. 2021 May 12;10(5):1184. doi: 10.3390/cells10051184. Cells. 2021. PMID: 34066164 Free PMC article. Review.
The B cell scaffold protein with ankyrin repeats (BANK1) is expressed primarily in B cells and with multiple but discrete roles in B cell signaling, including B cell receptor signaling, CD40-related signaling, and Toll-like receptor (TLR) signaling. .. …
The B cell scaffold protein with ankyrin repeats (BANK1) is expressed primarily in B cells and with multiple but discrete role …
Interferon and B-cell Signatures Inform Precision Medicine in Lupus Nephritis.
Parodis I, Lindblom J, Toro-Domínguez D, Beretta L, Borghi MO, Castillo J, Carnero-Montoro E, Enman Y, Mohan C, Alarcón-Riquelme ME, Barturen G, Nikolopoulos D; PRECISESADS Clinical Consortium. Parodis I, et al. Kidney Int Rep. 2024 Mar 13;9(6):1817-1835. doi: 10.1016/j.ekir.2024.03.014. eCollection 2024 Jun. Kidney Int Rep. 2024. PMID: 38899167 Free PMC article.
In silico analysis demonstrated the low-IFN subgroup to benefit from calcineurin inhibition and the intermediate-IFN subgroup from B-cell targeted therapies. High-IFN patients exhibited greater anticipated response to anifrolumab whereas daratumumab appeared beneficial to …
In silico analysis demonstrated the low-IFN subgroup to benefit from calcineurin inhibition and the intermediate-IFN subgroup from B- …
First-in-class transactivator-free, doxycycline-inducible IL-18-engineered CAR-T cells for relapsed/refractory B cell lymphomas.
Justicia-Lirio P, Tristán-Manzano M, Maldonado-Pérez N, Barbero-Jiménez C, Cortijo-Gutiérrez M, Pavlovic K, Molina-Estevez FJ, Muñoz P, Hinckley-Boned A, Rodriguez-Madoz JR, Prosper F, Griñán-Lison C, Navarro-Marchal SA, Panisello C, Muñoz-Ballester J, González-Sierra PA, Herrera C, Marchal JA, Martín F. Justicia-Lirio P, et al. Mol Ther Nucleic Acids. 2024 Aug 15;35(4):102308. doi: 10.1016/j.omtn.2024.102308. eCollection 2024 Dec 10. Mol Ther Nucleic Acids. 2024. PMID: 39640015 Free PMC article.
Although chimeric antigen receptor (CAR) T cell therapy has revolutionized type B cancer treatment, efficacy remains limited in various lymphomas and solid tumors. ...In a clinically relevant context, we generated patient-derived iTRUCK19.18 cells capable of eradicating pr …
Although chimeric antigen receptor (CAR) T cell therapy has revolutionized type B cancer treatment, efficacy remains limited in vario …
Investigation of HLA-B -21 M/T Dimorphism and Its Potential Role in COVID-19.
Martín-Rodríguez D, Gutiérrez-Bautista JF, Bernal M, Rodriguez-Nicolas A, Vílchez JR, Marín-Sánchez A, Rosales-Castillo A, Sainz J, Cabrera-Serrano AJ, Ceron-Hernandez J, López-Nevot MÁ, Ruiz-Cabello F, Jiménez P. Martín-Rodríguez D, et al. Int J Mol Sci. 2025 Jul 3;26(13):6419. doi: 10.3390/ijms26136419. Int J Mol Sci. 2025. PMID: 40650195 Free PMC article.
Their activity is regulated by a balance of activating and inhibitory signals, which are modulated by interactions with HLA class I molecules, including HLA-E. The HLA-B 21M/T dimorphism influences the availability of HLA-B leader peptides that stabilize HLA-E expre …
Their activity is regulated by a balance of activating and inhibitory signals, which are modulated by interactions with HLA class I molecule …
338 results