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43 results

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Page 1
Hepatic and renal improvements with FXR agonist vonafexor in individuals with suspected fibrotic NASH.
Ratziu V, Harrison SA, Loustaud-Ratti V, Bureau C, Lawitz E, Abdelmalek M, Alkhouri N, Francque S, Girma H, Darteil R, Couchoux H, Wolf M, Sanyal A, Vonderscher J, Scalfaro P. Ratziu V, et al. J Hepatol. 2023 Mar;78(3):479-492. doi: 10.1016/j.jhep.2022.10.023. Epub 2022 Nov 9. J Hepatol. 2023. PMID: 36334688 Free article. Clinical Trial.
Patients were randomised (1:1:1:1) to receive placebo, vonafexor 100 mg twice daily (VONA-100BID), vonafexor 200 mg once daily (VONA-200QD), or 400 mg vonafexor QD (VONA-400QD) in Part A (safety run-in, pharmacokinetics/pharmacodynamics) or placebo, vonafexor …
Patients were randomised (1:1:1:1) to receive placebo, vonafexor 100 mg twice daily (VONA-100BID), vonafexor 200 mg once daily (VO …
Cathepsin B inhibition interferes with metastatic potential of human melanoma: an in vitro and in vivo study.
Matarrese P, Ascione B, Ciarlo L, Vona R, Leonetti C, Scarsella M, Mileo AM, Catricalà C, Paggi MG, Malorni W. Matarrese P, et al. Mol Cancer. 2010 Aug 4;9:207. doi: 10.1186/1476-4598-9-207. Mol Cancer. 2010. PMID: 20684763 Free PMC article.
Among these are cysteinyl- (e.g. cathepsin B and cathepsin L) and aspartyl-proteases (e.g. cathepsin D), normally present inside the lysosomes as inactive proenzymes. ...CONCLUSIONS: These results suggest a reappraisal of the use of cathepsin B inhibitors (either ch …
Among these are cysteinyl- (e.g. cathepsin B and cathepsin L) and aspartyl-proteases (e.g. cathepsin D), normally present inside the …
Impact of Anion Exchange Ionomers on the Electrocatalytic Performance for the Oxygen Reduction Reaction of B-N Co-doped Carbon Quantum Dots on Activated Carbon.
Nallayagari AR, Sgreccia E, Pasquini L, Sette M, Knauth P, Di Vona ML. Nallayagari AR, et al. ACS Appl Mater Interfaces. 2022 Oct 19;14(41):46537-46547. doi: 10.1021/acsami.2c11802. Epub 2022 Oct 4. ACS Appl Mater Interfaces. 2022. PMID: 36194150
Composite electrocatalytic electrodes made from B-N co-doped carbon quantum dots (CQD) and various anion exchange ionomers (AEI) are studied for the oxygen reduction reaction (ORR) in alkaline solutions. The quantity and positions of dopants in CQD, prepared by hydrotherma …
Composite electrocatalytic electrodes made from B-N co-doped carbon quantum dots (CQD) and various anion exchange ionomers (AEI) are …
[Dynamic finite element analysis of three ferrule designs in post crown under impact loading].
Zhang XC, Chen HZ, Teng W, Wang Y, Fan YB, Jiang WT. Zhang XC, et al. Nan Fang Yi Ke Da Xue Xue Bao. 2008 Aug;28(9):1646-8. Nan Fang Yi Ke Da Xue Xue Bao. 2008. PMID: 18819889 Chinese.
The high stress areas were invariable at every loading step during dynamic loading. The peak stress was sigma(vonA)<sigma(vonC), sigma(vonB)<sigma(vonC), (P<0.05). The contrabevel had the minimal effect in decreasing the peak stress. CONCLUSIONS: When the ferrule …
The high stress areas were invariable at every loading step during dynamic loading. The peak stress was sigma(vonA)<sigma(vonC), s …
Constitutive localization of DR4 in lipid rafts is mandatory for TRAIL-induced apoptosis in B-cell hematologic malignancies.
Marconi M, Ascione B, Ciarlo L, Vona R, Garofalo T, Sorice M, Gianni AM, Locatelli SL, Carlo-Stella C, Malorni W, Matarrese P. Marconi M, et al. Cell Death Dis. 2013 Oct 17;4(10):e863. doi: 10.1038/cddis.2013.389. Cell Death Dis. 2013. PMID: 24136227 Free PMC article.
We performed a series of analyses, either by biochemical methods or fluorescence resonance energy transfer (FRET) technique, on normal cells (i.e. lymphocytes, fibroblasts, endothelial cells), on a panel of human cancer B-cell lines as well as on CD19(+) lymphocytes from p …
We performed a series of analyses, either by biochemical methods or fluorescence resonance energy transfer (FRET) technique, on normal cells …
Extravascular Ultrasound (EVUS) to Assess the Results of Peripheral Endovascular Procedures.
Fazzini S, Pennetta FF, Turriziani V, Vona S, Ascoli Marchetti A, Ippoliti A. Fazzini S, et al. Diagnostics (Basel). 2023 Apr 6;13(7):1356. doi: 10.3390/diagnostics13071356. Diagnostics (Basel). 2023. PMID: 37046574 Free PMC article.
By using a similar acronym, the intraoperative DUS has been previously described as extravascular ultrasound (EVUS). B-mode imaging, color flow, and peak systolic velocity (PSV) are considered. EVUS could be very useful to evaluate the effects of endovascular treatment, ma …
By using a similar acronym, the intraoperative DUS has been previously described as extravascular ultrasound (EVUS). B-mode imaging, …
43 results