The functional role of LncRNA HOXA-AS2 in multiple human cancers.
Khoshandam M, Sideris N, Ahmadieh-Yazdi A, Sheykhhasan M, Manoochehri H, Tanzadehpanah H, Mahaki H, Ghadam M, Lak S, Kalhor N, Rabiei M, Al-Musawi S, Dama P.
Khoshandam M, et al.
Pathol Res Pract. 2025 Feb;266:155795. doi: 10.1016/j.prp.2024.155795. Epub 2024 Dec 24.
Pathol Res Pract. 2025.
PMID: 39756105
Review.
The regulatory mechanisms of HOXA-AS2 include inducing epithelial-mesenchymal transition (EMT), overexpressing B-cell lymphoma-2 (Bcl-2) and MYC proto-oncogene (c-Myc), gene silencing, activating AKT-MMP signaling pathways, EZH2 and LSD1, and functioning within a competing …
The regulatory mechanisms of HOXA-AS2 include inducing epithelial-mesenchymal transition (EMT), overexpressing B-cell lymphoma-2 (Bcl …