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2012 1
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Page 1
Design, Synthesis and Biological Evaluation of New Imidazo[2,1-b]Thiazole Derivatives as Selective COX-2 Inhibitors.
Shahrasbi M, Azami Movahed M, Ghorban Dadras O, Daraei B, Zarghi A. Shahrasbi M, et al. Iran J Pharm Res. 2018 Fall;17(4):1288-1296. Iran J Pharm Res. 2018. PMID: 30568687 Free PMC article.
A new series of imidazo[2,1-b]thiazole analogs containing a methyl sulfonyl COX-2 pharmacophore was synthesized and evaluated for their COX-2 inhibitory activity. ...Our results indicated that both potency and selectivity of COX-2 inhibitory activity were affected by the t …
A new series of imidazo[2,1-b]thiazole analogs containing a methyl sulfonyl COX-2 pharmacophore was synthesized and evaluated for the …
Individual genetic variability mainly of Proinflammatory cytokines, cytokine receptors, and toll-like receptors dictates pathophysiology of COVID-19 disease.
Vakil MK, Mansoori Y, Al-Awsi GRL, Hosseinipour A, Ahsant S, Ahmadi S, Ekrahi M, Montaseri Z, Pezeshki B, Mohaghegh P, Sohrabpour M, Bahmanyar M, Daraei A, Dadkhah Jouybari T, Tavassoli A, Ghasemian A. Vakil MK, et al. J Med Virol. 2022 Sep;94(9):4088-4096. doi: 10.1002/jmv.27849. Epub 2022 May 31. J Med Virol. 2022. PMID: 35538614 Free PMC article. Review.
These variations mainly alter the gene expression and cause a severe response by B cells, T cells, monocytes, neutrophils, and natural killer cells participating in a cytokine storm. ...
These variations mainly alter the gene expression and cause a severe response by B cells, T cells, monocytes, neutrophils, and natura …
Hijacking and rewiring of host CircRNA/miRNA/mRNA competitive endogenous RNA (ceRNA) regulatory networks by oncoviruses during development of viral cancers.
Kamali MJ, Salehi M, Mostafavi M, Morovatshoar R, Akbari M, Latifi N, Barzegari O, Ghadimi F, Daraei A. Kamali MJ, et al. Rev Med Virol. 2024 Mar;34(2):e2530. doi: 10.1002/rmv.2530. Rev Med Virol. 2024. PMID: 38517354 Review.
This review focuses on a comprehensive evaluation of the latest findings on the involvement of virus-induced reprogramming of host circRNA-mediated ceRNA networks in the development and pathophysiology of human viral cancers, including cervical cancer, gastric cancer, nasopharyng …
This review focuses on a comprehensive evaluation of the latest findings on the involvement of virus-induced reprogramming of host circRNA-m …
Two novel anticancer compounds with minimum cardiotoxic property.
Afsharirad T, Tahmasvand R, Amini M, Daraei B, Salimi M. Afsharirad T, et al. BMC Pharmacol Toxicol. 2020 Nov 19;21(1):79. doi: 10.1186/s40360-020-00457-8. BMC Pharmacol Toxicol. 2020. PMID: 33213519 Free PMC article.
BACKGROUND: Although two novel synthesized compounds with tri-aryl structures; 3-(4-chlorophenyl)-5-(4-fluorophenyl)-4-phenyl-4,5-dihydro-1,2,4-oxadiazole (A) and 3,5-bis-(4-chlorophenyl)-4-phenyl-4,5-dihydro-1,2,4-oxadiazole (B) have been previously demonstrated to posses …
BACKGROUND: Although two novel synthesized compounds with tri-aryl structures; 3-(4-chlorophenyl)-5-(4-fluorophenyl)-4-phenyl-4,5-dihydro-1, …
Strength, deformability and toughness of uncrosslinked fibrin fibers from theoretical reconstruction of stress-strain curves.
Maksudov F, Daraei A, Sesha A, Marx KA, Guthold M, Barsegov V. Maksudov F, et al. Acta Biomater. 2021 Dec;136:327-342. doi: 10.1016/j.actbio.2021.09.050. Epub 2021 Oct 2. Acta Biomater. 2021. PMID: 34606991 Free PMC article.
We developed the Fluctuating Bilinear Spring model to interpret the sigma-epsilon profiles in terms of the free energy for protofibril alignment deltaG(0) = 10.1-11.5 k(B)T, Young's moduli for protofibril alignment Y(u) = 1.9-3.2 MPa and stretching Y(a) = 5.7-9.7 MPa, stra …
We developed the Fluctuating Bilinear Spring model to interpret the sigma-epsilon profiles in terms of the free energy for protofibril align …
Route exposure and adverse effects monitoring of Aflatoxin B1 in the workers of wet waste management, the role of body redox system modulation.
Karamkhani M, Asilian-Mahabadi H, Daraei B, Seidkhani-Nahal A, Noori-Zadeh A. Karamkhani M, et al. Ecotoxicol Environ Saf. 2022 Dec 15;248:114305. doi: 10.1016/j.ecoenv.2022.114305. Epub 2022 Nov 18. Ecotoxicol Environ Saf. 2022. PMID: 36403302 Free article.
Occupational evaluation of the aflatoxin's exposure-induced health abnormalities should include the monitoring of bioaerosols in the workplace and personal air, and applying of appropriate blood biomarkers to assess Aflatoxin B(1) (AFB(1)) detrimental effects on a worker's …
Occupational evaluation of the aflatoxin's exposure-induced health abnormalities should include the monitoring of bioaerosols in the workpla …
Validation of an UHPLC-MS/MS Method for Simultaneous Analysis of 11 Mycotoxins in Wheat Flour Using Immunoaffinity Column.
Heidari G, Hashemi Hazaveh SJ, Daraei B, Bayat M. Heidari G, et al. Iran J Pharm Res. 2019 Fall;18(Suppl1):182-189. doi: 10.22037/ijpr.2019.112398.13735. Iran J Pharm Res. 2019. PMID: 32802098 Free PMC article.
This study focuses on optimization and validation of an Ultrahigh-performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) method for simultaneous analysis of 11mycotoxins: Aflatoxins (B(1), B(2), G(1), and G(2)), Ochratoxin A, Deoxynivalenol, Fumoni …
This study focuses on optimization and validation of an Ultrahigh-performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) m …
Liver and kidney serum profile abnormalities in workers exposed to aflatoxin B1 in urban solid waste management centers.
Karamkhani M, Asilian-Mahabadi H, Daraei B, Seidkhani-Nahal A, Noori-Zadeh A. Karamkhani M, et al. Environ Monit Assess. 2020 Jun 30;192(7):472. doi: 10.1007/s10661-020-08422-y. Environ Monit Assess. 2020. PMID: 32607657
Many workers are exposed to health problems arising from molds, fungi, and their toxins during waste processing. Aflatoxin B(1) (AFB(1)) level in airborne and settled dust, aflatoxin B(1)-albumin (AFB(1)-Alb) adduct in serum, liver and kidney biochemical tests, and …
Many workers are exposed to health problems arising from molds, fungi, and their toxins during waste processing. Aflatoxin B(1) (AFB( …
One-year prevalence and the association between SARS-CoV-2 cycle threshold, comorbidity and outcomes in population of Babol, North of Iran (2020-2021).
Halaji M, Pournajaf A, Sadeghi F, Hasanzadeh A, Chehrazi M, Gholinia H, Hejazi Amiri F, Saber Amoli S, Javanian M, Bayani M, Sadeghi Haddad Zavareh M, Shokri M, Babazadeh A, Bazi Broun M, Mohammadi M, Mehdinezhad H, Monadi M, Amri Maleh P, Nouri HR, Daraei A, Yousefnia Pasha M, Tourani M, Ahmadian SR, Esmailzadeh N, Mirtabar SM, Asadi S, Yousefghahary B, Babaei M, Nabipour M, Vakili Sadeghi M, Pourkia R, Jafarypour I, Zieaie Amiri N, Akbary R, Asgharpour M, Oliaei F, Zahedpasha Y, Mahmoodi H, Akbarian Rad Z, Haghshenas Mojaveri M, Seyfi S, Shokri Shirvani J, Alhooee S, Abedi H, Behzad K, Bayani MA, Kheirkhah F, Saadat P, Nasiraie E, Ezami N, Gorjinejad S, Fallhpour K, Fakhraie F, Beheshti Y, Baghershiroodi M, Rasti F, Salehi M, Aleahmad A, Nasrollahian S, Babapour R, Malekzadeh R, Habibzadeh Kashi R, Shams Esmaili MA, Javadian Kotnaei M, Ghanbarpour A, Yahyapour Y. Halaji M, et al. Caspian J Intern Med. 2022;13(Suppl 3):244-253. doi: 10.22088/cjim.13.0.244. Caspian J Intern Med. 2022. PMID: 35872672 Free PMC article.
Furthermore, it seems that death rate was significantly different between the three groups of Ct value, the highest mortality in those with Ct between 21 and 30 (group B=7.6%) and the lowest in the group with the highest Ct (between 31 and 40 = 5.5%) (p<0.001). ...
Furthermore, it seems that death rate was significantly different between the three groups of Ct value, the highest mortality in those with …
20 results