Mutant p53 in bone marrow stromal cells increases VEGF expression and supports leukemia cell growth.
Narendran A, Ganjavi H, Morson N, Connor A, Barlow JW, Keystone E, Malkin D, Freedman MH.
Narendran A, et al.
Exp Hematol. 2003 Aug;31(8):693-701. doi: 10.1016/s0301-472x(03)00159-0.
Exp Hematol. 2003.
PMID: 12901974
Free article.
MATERIALS AND METHODS: We established an in vitro model consisting of stroma expressing mutant p53 (Cys135Ser) to study its ability to support growth of cells from a pre-B acute lymphoblastic leukemia (ALL) cell line. Normal and leukemic bone marrow stromal cells were scre …
MATERIALS AND METHODS: We established an in vitro model consisting of stroma expressing mutant p53 (Cys135Ser) to study its ability to suppo …