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2000 1
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914 results

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Page 1
B cell-derived acetylcholine promotes liver regeneration by regulating Kupffer cell and hepatic CD8(+) T cell function.
Modares NF, Hendrikse LD, Smith LK, Paul MS, Haight J, Luo P, Liu S, Fortin J, Tong FK, Wakeham AC, Jafari SM, Zheng C, Buckland M, Flick R, Silvester J, Berger T, Ketela T, Helke S, Foffi E, Niavarani R, Mcwilliam R, Saunders ME, Colonna I, David BA, Rastogi T, Lee WY, Kubes P, Mak TW. Modares NF, et al. Immunity. 2025 May 13;58(5):1201-1216.e7. doi: 10.1016/j.immuni.2025.04.002. Epub 2025 Apr 25. Immunity. 2025. PMID: 40286791 Free article.
Neurotransmitters such as acetylcholine (ACh) play a role in LR by stimulating immune cells and augmenting hepatocyte proliferation, but the source of this ACh remains unclear. Here, we demonstrated that B cells expressing choline acetyltransferase (ChAT), which synthesize …
Neurotransmitters such as acetylcholine (ACh) play a role in LR by stimulating immune cells and augmenting hepatocyte proliferation, but the …
Oxidative Stress in Liver Pathophysiology and Disease.
Allameh A, Niayesh-Mehr R, Aliarab A, Sebastiani G, Pantopoulos K. Allameh A, et al. Antioxidants (Basel). 2023 Aug 22;12(9):1653. doi: 10.3390/antiox12091653. Antioxidants (Basel). 2023. PMID: 37759956 Free PMC article. Review.
Thus, oxidative stress is implicated in acute liver injury and in the pathogenesis of prevalent infectious or metabolic chronic liver diseases such as viral hepatitis B or C, alcoholic fatty liver disease, non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatoh …
Thus, oxidative stress is implicated in acute liver injury and in the pathogenesis of prevalent infectious or metabolic chronic liver diseas …
Reply.
Behnke K, Zhuang Y, Xu HC, Sundaram B, Reich M, Shinde PV, Huang J, Modares NF, Tumanov AV, Polz R, Scheller J, Ware CF, Pfeffer K, Keitel V, Häussinger D, Pandyra AA, Lang KS, Lang PA. Behnke K, et al. Hepatology. 2019 Sep;70(3):1074-1075. doi: 10.1002/hep.30600. Hepatology. 2019. PMID: 30829412 No abstract available.
Noncoding RNAs in B cell non-Hodgkins lymphoma.
Abedi Kichi Z, Dini N, Rojhannezhad M, Shirvani Farsani Z. Abedi Kichi Z, et al. Gene. 2024 Jul 30;917:148480. doi: 10.1016/j.gene.2024.148480. Epub 2024 Apr 16. Gene. 2024. PMID: 38636814 Review.
B-cell non-Hodgkins lymphomas (BCNHLs) are a category of B-cell cancers that show heterogeneity. These blood disorders are derived from different levels of B-cell maturity. Among NHL cases, 80-90 % are derived from B-cells. Recent studies have demonst
B-cell non-Hodgkins lymphomas (BCNHLs) are a category of B-cell cancers that show heterogeneity. These blood disorders are der
Recent advances in monoclonal antibody development for treatment of B-cell acute lymphoblastic leukemia.
Kamalloo H, Fathi M, Bavandi S, Asadi F, Janati S, Amini K. Kamalloo H, et al. Leuk Lymphoma. 2025 Sep;66(9):1570-1582. doi: 10.1080/10428194.2025.2507198. Epub 2025 Jun 2. Leuk Lymphoma. 2025. PMID: 40455243 Review.
Monoclonal antibody (mAb)-based therapies targeting CD19, CD20, and CD22 have revolutionized B-ALL treatment, offering precision and reduced systemic toxicity by engaging immune mechanisms to eliminate leukemic cells. ...These innovations accelerate the development of next …
Monoclonal antibody (mAb)-based therapies targeting CD19, CD20, and CD22 have revolutionized B-ALL treatment, offering precision and …
Vitamins B(9) and B(12) in children with attention deficit hyperactivity disorder (ADHD).
Razavinia F, Ebrahimiyan A, Faal Siahkal S, Ghazinezhad N, Abedi P. Razavinia F, et al. Int J Vitam Nutr Res. 2024 Jun;94(5-6):476-484. doi: 10.1024/0300-9831/a000809. Int J Vitam Nutr Res. 2024. PMID: 38904980 Free article.
Background: Attention deficit hyperactivity disorder (ADHD) is a common childhood neurodevelopmental disorder that begins before age 12. Given the role of B group vitamins in cell metabolism, synthesis of nucleotides, and neurotransmitters, the present study systematically …
Background: Attention deficit hyperactivity disorder (ADHD) is a common childhood neurodevelopmental disorder that begins before age 12. Giv …
nACh receptors engage a nice ChAT with the liver: B cells serving up regeneration.
Schultheiß C, Binder M. Schultheiß C, et al. Immunity. 2025 May 13;58(5):1177-1179. doi: 10.1016/j.immuni.2025.04.021. Immunity. 2025. PMID: 40367919
Liver regeneration is a remarkable and unique biological process, orchestrated by an intricate cellular crosstalk of (non-)parenchymal, immune, and nerve cells. In this issue of Immunity, Modares et al. uncover the pivotal role of choline acetyltransferase (ChAT(+))-expres …
Liver regeneration is a remarkable and unique biological process, orchestrated by an intricate cellular crosstalk of (non-)parenchymal, immu …
microRNA-related single-nucleotide polymorphisms and breast cancer.
Bahreini F, Rayzan E, Rezaei N. Bahreini F, et al. J Cell Physiol. 2021 Mar;236(3):1593-1605. doi: 10.1002/jcp.29966. Epub 2020 Jul 27. J Cell Physiol. 2021. PMID: 32716070 Review.
In this regard, two principals were discussed: (a) SNPs in the target genes of microRNAs and the alteration in gene expression due to this phenomenon; (b) changes based on the SNPs in the microRNA coding region and the impact on their interaction with target messenger RNA. …
In this regard, two principals were discussed: (a) SNPs in the target genes of microRNAs and the alteration in gene expression due to this p …
Inactive Hepatitis B Carrier and Pregnancy Outcomes: A Systematic Review and Meta-analysis.
Keramat A, Younesian M, Gholami Fesharaki M, Hasani M, Mirzaei S, Ebrahimi E, Alavian SM, Mohammadi F. Keramat A, et al. Iran J Public Health. 2017 Apr;46(4):468-474. Iran J Public Health. 2017. PMID: 28540262 Free PMC article. Review.
BACKGROUND: We aimed to explore whether maternal asymptomatic hepatitis B (HB) infection effects on pre-term rupture of membranous (PROM), stillbirth, preeclampsia, eclampsia, gestational hypertension, or antepartum hemorrhage. ...
BACKGROUND: We aimed to explore whether maternal asymptomatic hepatitis B (HB) infection effects on pre-term rupture of membranous (P …
CD40 and tolerance induction.
Karimi MH, Pourfathollah AA. Karimi MH, et al. Iran J Allergy Asthma Immunol. 2012 Mar;11(1):1-13. Iran J Allergy Asthma Immunol. 2012. PMID: 22427471 Free article. Review.
According to these roles, it is assumed that CD40 is a functional molecule in the pathologies of conditions like autoimmune diseases and allograft rejection caused by activated T and B cells....
According to these roles, it is assumed that CD40 is a functional molecule in the pathologies of conditions like autoimmune diseases and all …
914 results