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Year Number of Results
2001 1
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2008 1
2009 1
2010 1
2011 1
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2013 3
2014 3
2015 9
2016 4
2017 7
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2019 9
2020 4
2021 15
2022 9
2023 12
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2025 1

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87 results

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Page 1
MiR-146a/b: a family with shared seeds and different roots.
Paterson MR, Kriegel AJ. Paterson MR, et al. Physiol Genomics. 2017 Apr 1;49(4):243-252. doi: 10.1152/physiolgenomics.00133.2016. Epub 2017 Feb 17. Physiol Genomics. 2017. PMID: 28213571 Free PMC article. Review.
A growing subset of the literature reports a role of miR-146 in cardiovascular and renal disease, and data suggest there is exciting potential for miR-146 as a diagnostic and therapeutic target. Nevertheless, the published literature is confounded by unclear and imp …
A growing subset of the literature reports a role of miR-146 in cardiovascular and renal disease, and data suggest there is exciting …
GSDMD-miR-223-NLRP3 axis involved in B(a)P-induced inflammatory injury of alveolar epithelial cells.
Kong X, Gao M, Liu Y, Zhang P, Li M, Ma P, Shang P, Wang W, Liu H, Zhang Q, Feng F. Kong X, et al. Ecotoxicol Environ Saf. 2022 Mar 1;232:113286. doi: 10.1016/j.ecoenv.2022.113286. Epub 2022 Feb 7. Ecotoxicol Environ Saf. 2022. PMID: 35144130 Free article.
However, whether GSDMD regulate NLRP3 inflammasome through miR-223 in B(a)P induced lung inflammatory injury remain unknown. In this study, alveolar epithelial cells (A549) were stimulated with 0, 2, 4, 8 muM B(a)P for 12 h or 24 h. ...Additiona …
However, whether GSDMD regulate NLRP3 inflammasome through miR-223 in B(a)P induced lung inflammatory injury remain unk …
miR-377-3p-Mediated EGR1 Downregulation Promotes B[a]P-Induced Lung Tumorigenesis by Wnt/Beta-Catenin Transduction.
Ke X, He L, Wang R, Shen J, Wang Z, Shen Y, Fan L, Shao J, Qi H. Ke X, et al. Front Oncol. 2021 Aug 23;11:699004. doi: 10.3389/fonc.2021.699004. eCollection 2021. Front Oncol. 2021. PMID: 34497759 Free PMC article.
Polycyclic aromatic hydrocarbons (PAHs), particularly benzo[a]pyrene (B[a]P), found in cigarette smoke and air pollution, is an important carcinogen. Nevertheless, early molecular events and related regulatory effects of B[a]P-mediated cell transformat …
Polycyclic aromatic hydrocarbons (PAHs), particularly benzo[a]pyrene (B[a]P), found in cigarette smoke and air pollution, is a …
Neoadjuvant-Adjuvant or Adjuvant-Only Pembrolizumab in Advanced Melanoma.
Patel SP, Othus M, Chen Y, Wright GP Jr, Yost KJ, Hyngstrom JR, Hu-Lieskovan S, Lao CD, Fecher LA, Truong TG, Eisenstein JL, Chandra S, Sosman JA, Kendra KL, Wu RC, Devoe CE, Deutsch GB, Hegde A, Khalil M, Mangla A, Reese AM, Ross MI, Poklepovic AS, Phan GQ, Onitilo AA, Yasar DG, Powers BC, Doolittle GC, In GK, Kokot N, Gibney GT, Atkins MB, Shaheen M, Warneke JA, Ikeguchi A, Najera JE, Chmielowski B, Crompton JG, Floyd JD, Hsueh E, Margolin KA, Chow WA, Grossmann KF, Dietrich E, Prieto VG, Lowe MC, Buchbinder EI, Kirkwood JM, Korde L, Moon J, Sharon E, Sondak VK, Ribas A. Patel SP, et al. N Engl J Med. 2023 Mar 2;388(9):813-823. doi: 10.1056/NEJMoa2211437. N Engl J Med. 2023. PMID: 36856617 Free PMC article. Clinical Trial.
New insights into the genetic etiology of Alzheimer's disease and related dementias.
Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, Kuulasmaa T, Yang Q, de Rojas I, Bis JC, Yaqub A, Prokic I, Chapuis J, Ahmad S, Giedraitis V, Aarsland D, Garcia-Gonzalez P, Abdelnour C, Alarcón-Martín E, Alcolea D, Alegret M, Alvarez I, Álvarez V, Armstrong NJ, Tsolaki A, Antúnez C, Appollonio I, Arcaro M, Archetti S, Pastor AA, Arosio B, Athanasiu L, Bailly H, Banaj N, Baquero M, Barral S, Beiser A, Pastor AB, Below JE, Benchek P, Benussi L, Berr C, Besse C, Bessi V, Binetti G, Bizarro A, Blesa R, Boada M, Boerwinkle E, Borroni B, Boschi S, Bossù P, Bråthen G, Bressler J, Bresner C, Brodaty H, Brookes KJ, Brusco LI, Buiza-Rueda D, Bûrger K, Burholt V, Bush WS, Calero M, Cantwell LB, Chene G, Chung J, Cuccaro ML, Carracedo Á, Cecchetti R, Cervera-Carles L, Charbonnier C, Chen HH, Chillotti C, Ciccone S, Claassen JAHR, Clark C, Conti E, Corma-Gómez A, Costantini E, Custodero C, Daian D, Dalmasso MC, Daniele A, Dardiotis E, Dartigues JF, de Deyn PP, de Paiva Lopes K, de Witte LD, Debette S, Deckert J, Del Ser T, Denning N, DeStefano A, Dichgans M,… See abstract for full author list ➔ Bellenguez C, et al. Nat Genet. 2022 Apr;54(4):412-436. doi: 10.1038/s41588-022-01024-z. Epub 2022 Apr 4. Nat Genet. 2022. PMID: 35379992 Free PMC article.
ATG7 upregulation contributes to malignant transformation of human bronchial epithelial cells by B[a]PDE via DNMT3B protein degradation and miR-494 promoter methylation.
Tian Z, Hua X, Zhu J, Li P, Chen R, Li X, Li T, Zhou C, Huang C. Tian Z, et al. Ecotoxicol Environ Saf. 2023 Sep 15;263:115273. doi: 10.1016/j.ecoenv.2023.115273. Epub 2023 Jul 20. Ecotoxicol Environ Saf. 2023. PMID: 37480691 Free article.
However, the potential alterations of ATG7 and its role in B[a]PDE-caused lung carcinogenesis remain unknown. Here, we found that B[a]PDE exposure promoted ATG7 expression in mouse lung tissues, while B[a]PDE exposure resulted in ATG7 ind …
However, the potential alterations of ATG7 and its role in B[a]PDE-caused lung carcinogenesis remain unknown. Here, we found t …
Exposure of benzo[a]pyrene induces HCC exosome-circular RNA to activate lung fibroblasts and trigger organotropic metastasis.
Mu W, Gu P, Li H, Zhou J, Jian Y, Jia W, Ge Y. Mu W, et al. Cancer Commun (Lond). 2024 Jul;44(7):718-738. doi: 10.1002/cac2.12574. Epub 2024 Jun 5. Cancer Commun (Lond). 2024. PMID: 38840551 Free PMC article.
Chronic exposure of B[a]P in hepatocellular carcinoma (HCC) cells promotes metastasis rather than primary proliferation, implying an unknown mechanism of B[a]P-induced malignancy. ...Compared to non-exposed 7404 cells, circ_0011496 was up-regulated fol …
Chronic exposure of B[a]P in hepatocellular carcinoma (HCC) cells promotes metastasis rather than primary proliferation, imply …
miR-17 acts as a tumor suppressor by negatively regulating the miR-17-92 cluster.
Sweat Y, Ries RJ, Sweat M, Su D, Shao F, Eliason S, Amendt BA. Sweat Y, et al. Mol Ther Nucleic Acids. 2021 Oct 21;26:1148-1158. doi: 10.1016/j.omtn.2021.10.021. eCollection 2021 Dec 3. Mol Ther Nucleic Acids. 2021. PMID: 34853714 Free PMC article.
Surprisingly, miR-17 inhibition increased expression of the miR-17-92 cluster and significantly increased the levels of the miR-18a and miR-19a mature miRs. miR-17 inhibition increased expression of the cell cycle activator CCND2, associated wit …
Surprisingly, miR-17 inhibition increased expression of the miR-17-92 cluster and significantly increased the levels of the …
PHLPP2 Downregulation Contributes to Lung Carcinogenesis Following B[a]P/B[a]PDE Exposure.
Huang H, Pan X, Jin H, Li Y, Zhang L, Yang C, Liu P, Liu Y, Chen L, Li J, Zhu J, Zeng X, Fu K, Chen G, Gao J, Huang C. Huang H, et al. Clin Cancer Res. 2015 Aug 15;21(16):3783-93. doi: 10.1158/1078-0432.CCR-14-2829. Epub 2015 May 14. Clin Cancer Res. 2015. PMID: 25977341 Free PMC article.
PURPOSE: The carcinogenic capacity of B[a]P/B[a]PDE is supported by epidemiologic studies. However, the molecular mechanisms responsible for B[a]P/B[a]PDE-caused lung cancer have not been well investigated. ...Additional stu …
PURPOSE: The carcinogenic capacity of B[a]P/B[a]PDE is supported by epidemiologic studies. However, the molecula …
Is the Non-Coding RNA miR-195 a Biodynamic Marker in the Pathogenesis of Head and Neck Squamous Cell Carcinoma? A Prognostic Meta-Analysis.
Dioguardi M, Spirito F, Caloro GA, Lo Muzio L, Cantore S, Ballini A, Scacco S, Malcangi A, Sembronio S, Cascardi E, Arrigoni R, Di Cosola M, Nocini R. Dioguardi M, et al. J Pers Med. 2023 Jan 31;13(2):275. doi: 10.3390/jpm13020275. J Pers Med. 2023. PMID: 36836509 Free PMC article. Review.
The etiopathogenetic mechanisms involving tumor genesis including the alteration of cell proliferation, apoptosis, invasion, migration, and death may involve alterations in the expression of microRNA (miR). To date there have been no systematic reviews with meta-analysis c …
The etiopathogenetic mechanisms involving tumor genesis including the alteration of cell proliferation, apoptosis, invasion, migration, and …
87 results