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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 13
1946 15
1947 26
1948 26
1949 24
1950 32
1951 23
1952 31
1953 34
1954 31
1955 34
1956 33
1957 33
1958 37
1959 38
1960 38
1961 38
1962 35
1963 38
1964 43
1965 67
1966 46
1967 53
1968 48
1969 58
1970 61
1971 62
1972 66
1973 66
1974 63
1975 46
1976 42
1977 41
1978 35
1979 41
1980 45
1981 40
1982 37
1983 52
1984 64
1985 53
1986 70
1987 90
1988 81
1989 85
1990 103
1991 155
1992 107
1993 91
1994 112
1995 124
1996 173
1997 169
1998 187
1999 192
2000 217
2001 218
2002 231
2003 287
2004 288
2005 341
2006 345
2007 349
2008 366
2009 372
2010 372
2011 367
2012 354
2013 405
2014 433
2015 477
2016 406
2017 375
2018 383
2019 404
2020 427
2021 276
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Search Results

10,492 results
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Page 1
Brain-first versus body-first Parkinson's disease: a multimodal imaging case-control study.
Horsager J, Andersen KB, Knudsen K, Skjærbæk C, Fedorova TD, Okkels N, Schaeffer E, Bonkat SK, Geday J, Otto M, Sommerauer M, Danielsen EH, Bech E, Kraft J, Munk OL, Hansen SD, Pavese N, Göder R, Brooks DJ, Berg D, Borghammer P. Horsager J, et al. Brain. 2020 Oct 1;143(10):3077-3088. doi: 10.1093/brain/awaa238. Brain. 2020. PMID: 32830221
We have hypothesized that Parkinson's disease comprises two subtypes. A brain-first (top-down) type, where alpha-synuclein pathology initially arises in the brain with secondary spreading to the peripheral autonomic nervous system; and a body-first (bottom-up) type, …
We have hypothesized that Parkinson's disease comprises two subtypes. A brain-first (top-down) type, where alpha-synuclein pathology …
The emerging spectrum of COVID-19 neurology: clinical, radiological and laboratory findings.
Paterson RW, Brown RL, Benjamin L, Nortley R, Wiethoff S, Bharucha T, Jayaseelan DL, Kumar G, Raftopoulos RE, Zambreanu L, Vivekanandam V, Khoo A, Geraldes R, Chinthapalli K, Boyd E, Tuzlali H, Price G, Christofi G, Morrow J, McNamara P, McLoughlin B, Lim ST, Mehta PR, Levee V, Keddie S, Yong W, Trip SA, Foulkes AJM, Hotton G, Miller TD, Everitt AD, Carswell C, Davies NWS, Yoong M, Attwell D, Sreedharan J, Silber E, Schott JM, Chandratheva A, Perry RJ, Simister R, Checkley A, Longley N, Farmer SF, Carletti F, Houlihan C, Thom M, Lunn MP, Spillane J, Howard R, Vincent A, Werring DJ, Hoskote C, Jäger HR, Manji H, Zandi MS. Paterson RW, et al. Brain. 2020 Oct 1;143(10):3104-3120. doi: 10.1093/brain/awaa240. Brain. 2020. PMID: 32637987 Free PMC article.
Slow blood-to-brain transport underlies enduring barrier dysfunction in American football players.
Veksler R, Vazana U, Serlin Y, Prager O, Ofer J, Shemen N, Fisher AM, Minaeva O, Hua N, Saar-Ashkenazy R, Benou I, Riklin-Raviv T, Parker E, Mumby G, Kamintsky L, Beyea S, Bowen CV, Shelef I, O'Keeffe E, Campbell M, Kaufer D, Goldstein LE, Friedman A. Veksler R, et al. Brain. 2020 Jun 1;143(6):1826-1842. doi: 10.1093/brain/awaa140. Brain. 2020. PMID: 32464655 Free PMC article.
While the mechanisms underlying repetitive mild traumatic brain injury-induced neurodegeneration are unknown and antemortem diagnostic tests are not available, neuropathology studies suggest a pathogenic role for microvascular injury, specifically blood-brain barrie …
While the mechanisms underlying repetitive mild traumatic brain injury-induced neurodegeneration are unknown and antemortem diagnosti …
KMT2B-related disorders: expansion of the phenotypic spectrum and long-term efficacy of deep brain stimulation.
Cif L, Demailly D, Lin JP, Barwick KE, Sa M, Abela L, Malhotra S, Chong WK, Steel D, Sanchis-Juan A, Ngoh A, Trump N, Meyer E, Vasques X, Rankin J, Allain MW, Applegate CD, Attaripour Isfahani S, Baleine J, Balint B, Bassetti JA, Baple EL, Bhatia KP, Blanchet C, Burglen L, Cambonie G, Seng EC, Bastaraud SC, Cyprien F, Coubes C, d'Hardemare V; Deciphering Developmental Disorders Study, Doja A, Dorison N, Doummar D, Dy-Hollins ME, Farrelly E, Fitzpatrick DR, Fearon C, Fieg EL, Fogel BL, Forman EB, Fox RG; Genomics England Research Consortium, Gahl WA, Galosi S, Gonzalez V, Graves TD, Gregory A, Hallett M, Hasegawa H, Hayflick SJ, Hamosh A, Hully M, Jansen S, Jeong SY, Krier JB, Krystal S, Kumar KR, Laurencin C, Lee H, Lesca G, François LL, Lynch T, Mahant N, Martinez-Agosto JA, Milesi C, Mills KA, Mondain M, Morales-Briceno H; NIHR BioResource, Ostergaard JR, Pal S, Pallais JC, Pavillard F, Perrigault PF, Petersen AK, Polo G, Poulen G, Rinne T, Roujeau T, Rogers C, Roubertie A, Sahagian M, Schaefer E, Selim L, Selway R, Sharma N, Signer R, Soldatos AG, Stevenson DA, Stewart F, Tchan M; Undiagnosed Diseases Network, Verma IC, de Vries BBA, Wilson JL, Wong DA, Zaitoun R, Zhen D, Znaczko A, Dale RC, de Gusmão CM, Friedman J, Fung VSC, King MD, Mohammad SS, Rohena L, Waugh JL, Toro C, Raymond FL, Topf M, Coubes P, Gorman KM, Kurian MA. Cif L, et al. Brain. 2020 Dec 5;143(11):3242-3261. doi: 10.1093/brain/awaa304. Brain. 2020. PMID: 33150406
Eighteen individuals had detailed longitudinal data available after insertion of deep brain stimulation for medically refractory dystonia. Median age at deep brain stimulation was 11.5 years (range: 4.5-37.0 years). ...In the long-term deep brain stimulation …
Eighteen individuals had detailed longitudinal data available after insertion of deep brain stimulation for medically refractory dyst …
Brain cancer induces systemic immunosuppression through release of non-steroid soluble mediators.
Ayasoufi K, Pfaller CK, Evgin L, Khadka RH, Tritz ZP, Goddery EN, Fain CE, Yokanovich LT, Himes BT, Jin F, Zheng J, Schuelke MR, Hansen MJ, Tung W, Parney IF, Pease LR, Vile RG, Johnson AJ. Ayasoufi K, et al. Brain. 2020 Dec 1;143(12):3629-3652. doi: 10.1093/brain/awaa343. Brain. 2020. PMID: 33253355
We determined that thymic involution was a hallmark feature of immunosuppression in three distinct models of brain cancer, including mice harbouring GL261 glioma, B16 melanoma, and in a spontaneous model of diffuse intrinsic pontine glioma. ...Both thymic involution and se …
We determined that thymic involution was a hallmark feature of immunosuppression in three distinct models of brain cancer, including …
Microglial exosomes facilitate α-synuclein transmission in Parkinson's disease.
Guo M, Wang J, Zhao Y, Feng Y, Han S, Dong Q, Cui M, Tieu K. Guo M, et al. Brain. 2020 May 1;143(5):1476-1497. doi: 10.1093/brain/awaa090. Brain. 2020. PMID: 32355963 Free PMC article.
Given the increasing recognition of the importance of non-cell autonomous-mediated neurotoxicity, it is critical to investigate the contribution of glia to alpha-synuclein aggregation and spread. Microglia are the primary phagocytes in the brain and have been well-document …
Given the increasing recognition of the importance of non-cell autonomous-mediated neurotoxicity, it is critical to investigate the contribu …
Diffuse axonal injury predicts neurodegeneration after moderate-severe traumatic brain injury.
Graham NSN, Jolly A, Zimmerman K, Bourke NJ, Scott G, Cole JH, Schott JM, Sharp DJ. Graham NSN, et al. Brain. 2020 Dec 1;143(12):3685-3698. doi: 10.1093/brain/awaa316. Brain. 2020. PMID: 33099608
Traumatic brain injury is associated with elevated rates of neurodegenerative diseases such as Alzheimer's disease and chronic traumatic encephalopathy. ...No significant changes in fractional anisotropy over time were observed. In contrast, abnormally high rates of bra
Traumatic brain injury is associated with elevated rates of neurodegenerative diseases such as Alzheimer's disease and chronic trauma …
Tissue-resident memory T cells invade the brain parenchyma in multiple sclerosis white matter lesions.
Fransen NL, Hsiao CC, van der Poel M, Engelenburg HJ, Verdaasdonk K, Vincenten MCJ, Remmerswaal EBM, Kuhlmann T, Mason MRJ, Hamann J, Smolders J, Huitinga I. Fransen NL, et al. Brain. 2020 Jun 1;143(6):1714-1730. doi: 10.1093/brain/awaa117. Brain. 2020. PMID: 32400866
The location of CD8+ T cells in either the perivascular space or the brain parenchyma was determined using CD8/laminin staining and confocal imaging. ...Inflammatory active multiple sclerosis lesions are populated by CD8+ tissue-resident memory T cells, which show signs of …
The location of CD8+ T cells in either the perivascular space or the brain parenchyma was determined using CD8/laminin staining and c …
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