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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
1999 1
2000 1
2002 1
2004 3
2005 6
2006 7
2007 11
2008 10
2009 8
2010 12
2011 6
2012 12
2013 15
2014 22
2015 13
2016 14
2017 25
2018 24
2019 16
2020 19
2021 23
2022 10
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241 results
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Page 1
CRISPR-Cas bioinformatics.
Alkhnbashi OS, Meier T, Mitrofanov A, Backofen R, Voß B. Alkhnbashi OS, et al. Among authors: backofen r. Methods. 2020 Feb 1;172:3-11. doi: 10.1016/j.ymeth.2019.07.013. Epub 2019 Jul 19. Methods. 2020. PMID: 31326596 Review.
An updated evolutionary classification of CRISPR-Cas systems.
Makarova KS, Wolf YI, Alkhnbashi OS, Costa F, Shah SA, Saunders SJ, Barrangou R, Brouns SJ, Charpentier E, Haft DH, Horvath P, Moineau S, Mojica FJ, Terns RM, Terns MP, White MF, Yakunin AF, Garrett RA, van der Oost J, Backofen R, Koonin EV. Makarova KS, et al. Among authors: backofen r. Nat Rev Microbiol. 2015 Nov;13(11):722-36. doi: 10.1038/nrmicro3569. Epub 2015 Sep 28. Nat Rev Microbiol. 2015. PMID: 26411297 Free PMC article. Review.
Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants.
Makarova KS, Wolf YI, Iranzo J, Shmakov SA, Alkhnbashi OS, Brouns SJJ, Charpentier E, Cheng D, Haft DH, Horvath P, Moineau S, Mojica FJM, Scott D, Shah SA, Siksnys V, Terns MP, Venclovas Č, White MF, Yakunin AF, Yan W, Zhang F, Garrett RA, Backofen R, van der Oost J, Barrangou R, Koonin EV. Makarova KS, et al. Among authors: backofen r. Nat Rev Microbiol. 2020 Feb;18(2):67-83. doi: 10.1038/s41579-019-0299-x. Epub 2019 Dec 19. Nat Rev Microbiol. 2020. PMID: 31857715 Free PMC article. Review.
Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N6-carboxymethyllysine.
Mossad O, Batut B, Yilmaz B, Dokalis N, Mezö C, Nent E, Nabavi LS, Mayer M, Maron FJM, Buescher JM, de Agüero MG, Szalay A, Lämmermann T, Macpherson AJ, Ganal-Vonarburg SC, Backofen R, Erny D, Prinz M, Blank T. Mossad O, et al. Among authors: backofen r. Nat Neurosci. 2022 Mar;25(3):295-305. doi: 10.1038/s41593-022-01027-3. Epub 2022 Mar 3. Nat Neurosci. 2022. PMID: 35241804
Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations.
Schubert D, Bode C, Kenefeck R, Hou TZ, Wing JB, Kennedy A, Bulashevska A, Petersen BS, Schäffer AA, Grüning BA, Unger S, Frede N, Baumann U, Witte T, Schmidt RE, Dueckers G, Niehues T, Seneviratne S, Kanariou M, Speckmann C, Ehl S, Rensing-Ehl A, Warnatz K, Rakhmanov M, Thimme R, Hasselblatt P, Emmerich F, Cathomen T, Backofen R, Fisch P, Seidl M, May A, Schmitt-Graeff A, Ikemizu S, Salzer U, Franke A, Sakaguchi S, Walker LSK, Sansom DM, Grimbacher B. Schubert D, et al. Among authors: backofen r. Nat Med. 2014 Dec;20(12):1410-1416. doi: 10.1038/nm.3746. Epub 2014 Oct 20. Nat Med. 2014. PMID: 25329329 Free PMC article.
Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration.
Clapes T, Polyzou A, Prater P, Sagar, Morales-Hernández A, Ferrarini MG, Kehrer N, Lefkopoulos S, Bergo V, Hummel B, Obier N, Maticzka D, Bridgeman A, Herman JS, Ilik I, Klaeylé L, Rehwinkel J, McKinney-Freeman S, Backofen R, Akhtar A, Cabezas-Wallscheid N, Sawarkar R, Rebollo R, Grün D, Trompouki E. Clapes T, et al. Among authors: backofen r. Nat Cell Biol. 2021 Jul;23(7):704-717. doi: 10.1038/s41556-021-00707-9. Epub 2021 Jul 12. Nat Cell Biol. 2021. PMID: 34253898 Free PMC article.
CRISPRtracrRNA: robust approach for CRISPR tracrRNA detection.
Mitrofanov A, Ziemann M, Alkhnbashi OS, Hess WR, Backofen R. Mitrofanov A, et al. Among authors: backofen r. Bioinformatics. 2022 Sep 16;38(Supplement_2):ii42-ii48. doi: 10.1093/bioinformatics/btac466. Bioinformatics. 2022. PMID: 36124799 Free PMC article.
Characterizing leader sequences of CRISPR loci.
Alkhnbashi OS, Shah SA, Garrett RA, Saunders SJ, Costa F, Backofen R. Alkhnbashi OS, et al. Among authors: backofen r. Bioinformatics. 2016 Sep 1;32(17):i576-i585. doi: 10.1093/bioinformatics/btw454. Bioinformatics. 2016. PMID: 27587677
antaRNA: ant colony-based RNA sequence design.
Kleinkauf R, Mann M, Backofen R. Kleinkauf R, et al. Among authors: backofen r. Bioinformatics. 2015 Oct 1;31(19):3114-21. doi: 10.1093/bioinformatics/btv319. Epub 2015 May 27. Bioinformatics. 2015. PMID: 26023105 Free PMC article.
241 results