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Page 1
A Monoclonal Antibody for Malaria Prevention.
Gaudinski MR, Berkowitz NM, Idris AH, Coates EE, Holman LA, Mendoza F, Gordon IJ, Plummer SH, Trofymenko O, Hu Z, Campos Chagas A, O'Connell S, Basappa M, Douek N, Narpala SR, Barry CR, Widge AT, Hicks R, Awan SF, Wu RL, Hickman S, Wycuff D, Stein JA, Case C, Evans BP, Carlton K, Gall JG, Vazquez S, Flach B, Chen GL, Francica JR, Flynn BJ, Kisalu NK, Capparelli EV, McDermott A, Mascola JR, Ledgerwood JE, Seder RA; VRC 612 Study Team. Gaudinski MR, et al. Among authors: basappa m. N Engl J Med. 2021 Aug 26;385(9):803-814. doi: 10.1056/NEJMoa2034031. Epub 2021 Aug 11. N Engl J Med. 2021. PMID: 34379916 Clinical Trial.
A majority of uninfected adults show preexisting antibody reactivity against SARS-CoV-2.
Majdoubi A, Michalski C, O'Connell SE, Dada S, Narpala S, Gelinas J, Mehta D, Cheung C, Winkler DF, Basappa M, Liu AC, Görges M, Barakauskas VE, Irvine M, Mehalko J, Esposito D, Sekirov I, Jassem AN, Goldfarb DM, Pelech S, Douek DC, McDermott AB, Lavoie PM. Majdoubi A, et al. Among authors: basappa m. JCI Insight. 2021 Apr 22;6(8):e146316. doi: 10.1172/jci.insight.146316. JCI Insight. 2021. PMID: 33720905 Free PMC article.
Antibody reactivity to SARS-CoV-2 is common in unexposed adults and infants under 6 months.
Majdoubi A, Michalski C, O'Connell SE, Dada S, Narpala S, Gelinas J, Mehta D, Cheung C, Basappa M, Liu AC, Gorges M, Barakauskas VE, Mehalko J, Esposito D, Sekirov I, Jassem AN, Goldfarb DM, Douek DC, McDermott AB, Lavoie PM. Majdoubi A, et al. Among authors: basappa m. medRxiv. 2020 Nov 6:2020.10.05.20206664. doi: 10.1101/2020.10.05.20206664. Preprint. medRxiv. 2020. PMID: 33052362 Free PMC article.
Fusion peptide priming reduces immune responses to HIV-1 envelope trimer base.
Corrigan AR, Duan H, Cheng C, Gonelli CA, Ou L, Xu K, DeMouth ME, Geng H, Narpala S, O'Connell S, Zhang B, Zhou T, Basappa M, Boyington JC, Chen SJ, O'Dell S, Pegu A, Stephens T, Tsybovsky Y, van Schooten J, Todd JP, Wang S; VRC Production Program, Doria-Rose NA, Foulds KE, Koup RA, McDermott AB, van Gils MJ, Kwong PD, Mascola JR. Corrigan AR, et al. Among authors: basappa m. Cell Rep. 2021 Apr 6;35(1):108937. doi: 10.1016/j.celrep.2021.108937. Cell Rep. 2021. PMID: 33826898 Free PMC article.