Bauman JN[au] - Search Results

Year	Number of Results
2002	1
2005	1
2006	1
2007	2
2008	2
2009	3
2010	3
2011	1
2012	1
2014	2
2015	1
2016	1
2022	1

1

In Vitro Kinetic Characterization of Axitinib Metabolism.

Zientek MA, Goosen TC, Tseng E, Lin J, Bauman JN, Walker GS, Kang P, Jiang Y, Freiwald S, Neul D, Smith BJ. Zientek MA, et al. Among authors: bauman jn. Drug Metab Dispos. 2016 Jan;44(1):102-14. doi: 10.1124/dmd.115.065615. Epub 2015 Oct 28. Drug Metab Dispos. 2016. PMID: 26512042

2

Metabolism-guided design of short-acting calcium-sensing receptor antagonists.

Southers JA, Bauman JN, Price DA, Humphries PS, Balan G, Sagal JF, Maurer TS, Zhang Y, Oliver R, Herr M, Healy DR, Li M, Kapinos B, Fate GD, Riccardi KA, Paralkar VM, Brown TA, Kalgutkar AS. Southers JA, et al. Among authors: bauman jn. ACS Med Chem Lett. 2010 May 13;1(5):219-23. doi: 10.1021/ml100058w. eCollection 2010 Aug 12. ACS Med Chem Lett. 2010. PMID: 24900198 Free PMC article.

3

Undesired versus designed enzymatic cleavage of linkers for liver targeting.

Chirapu SR, Bauman JN, Eng H, Goosen TC, Strelevitz TJ, Sinha SC, Dow RL, Finn MG. Chirapu SR, et al. Among authors: bauman jn. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1144-7. doi: 10.1016/j.bmcl.2013.12.126. Epub 2014 Jan 8. Bioorg Med Chem Lett. 2014. PMID: 24461291 Free PMC article.

4

The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Abrocitinib, a Selective Janus Kinase Inhibitor, in Humans.

Bauman JN, Doran AC, King-Ahmad A, Sharma R, Walker GS, Lin J, Lin TH, Telliez JB, Tripathy S, Goosen TC, Banfield C, Malhotra BK, Dowty ME. Bauman JN, et al. Drug Metab Dispos. 2022 Jun 14:DMD-AR-2022-000829. doi: 10.1124/dmd.122.000829. Online ahead of print. Drug Metab Dispos. 2022. PMID: 35701182 Free article.

5

On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffolds.

White TR, Renzelman CM, Rand AC, Rezai T, McEwen CM, Gelev VM, Turner RA, Linington RG, Leung SS, Kalgutkar AS, Bauman JN, Zhang Y, Liras S, Price DA, Mathiowetz AM, Jacobson MP, Lokey RS. White TR, et al. Among authors: bauman jn. Nat Chem Biol. 2011 Sep 25;7(11):810-7. doi: 10.1038/nchembio.664. Nat Chem Biol. 2011. PMID: 21946276 Free PMC article.

6

Biosynthesis of drug metabolites and quantitation using NMR spectroscopy for use in pharmacologic and drug metabolism studies.

Walker GS, Bauman JN, Ryder TF, Smith EB, Spracklin DK, Obach RS. Walker GS, et al. Among authors: bauman jn. Drug Metab Dispos. 2014 Oct;42(10):1627-39. doi: 10.1124/dmd.114.059204. Epub 2014 Jul 22. Drug Metab Dispos. 2014. PMID: 25053618

7

Trifluoromethylpyrimidine-based inhibitors of proline-rich tyrosine kinase 2 (PYK2): structure-activity relationships and strategies for the elimination of reactive metabolite formation.

Walker DP, Bi FC, Kalgutkar AS, Bauman JN, Zhao SX, Soglia JR, Aspnes GE, Kung DW, Klug-McLeod J, Zawistoski MP, McGlynn MA, Oliver R, Dunn M, Li JC, Richter DT, Cooper BA, Kath JC, Hulford CA, Autry CL, Luzzio MJ, Ung EJ, Roberts WG, Bonnette PC, Buckbinder L, Mistry A, Griffor MC, Han S, Guzman-Perez A. Walker DP, et al. Among authors: bauman jn. Bioorg Med Chem Lett. 2008 Dec 1;18(23):6071-7. doi: 10.1016/j.bmcl.2008.10.030. Epub 2008 Oct 11. Bioorg Med Chem Lett. 2008. PMID: 18951788

8

Optimized assays for human UDP-glucuronosyltransferase (UGT) activities: altered alamethicin concentration and utility to screen for UGT inhibitors.

Walsky RL, Bauman JN, Bourcier K, Giddens G, Lapham K, Negahban A, Ryder TF, Obach RS, Hyland R, Goosen TC. Walsky RL, et al. Among authors: bauman jn. Drug Metab Dispos. 2012 May;40(5):1051-65. doi: 10.1124/dmd.111.043117. Epub 2012 Feb 22. Drug Metab Dispos. 2012. PMID: 22357286

9

Atorvastatin glucuronidation is minimally and nonselectively inhibited by the fibrates gemfibrozil, fenofibrate, and fenofibric acid.

Goosen TC, Bauman JN, Davis JA, Yu C, Hurst SI, Williams JA, Loi CM. Goosen TC, et al. Among authors: bauman jn. Drug Metab Dispos. 2007 Aug;35(8):1315-24. doi: 10.1124/dmd.107.015230. Epub 2007 Apr 30. Drug Metab Dispos. 2007. PMID: 17470524

10

Udp-glucuronosyltransferase 2b7 is the major enzyme responsible for gemcabene glucuronidation in human liver microsomes.

Bauman JN, Goosen TC, Tugnait M, Peterkin V, Hurst SI, Menning LC, Milad M, Court MH, Williams JA. Bauman JN, et al. Drug Metab Dispos. 2005 Sep;33(9):1349-54. doi: 10.1124/dmd.105.005108. Epub 2005 Jun 24. Drug Metab Dispos. 2005. PMID: 15980101

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