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Deciphering bacterial epigenomes using modern sequencing technologies.

Beaulaurier J, Schadt EE, Fang G. Beaulaurier J, et al. Nat Rev Genet. 2019 Mar;20(3):157-172. doi: 10.1038/s41576-018-0081-3. Nat Rev Genet. 2019. PMID: 30546107 Free PMC article. Review.

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Assembly-free single-molecule sequencing recovers complete virus genomes from natural microbial communities.

Beaulaurier J, Luo E, Eppley JM, Uyl PD, Dai X, Burger A, Turner DJ, Pendelton M, Juul S, Harrington E, DeLong EF. Beaulaurier J, et al. Genome Res. 2020 Mar;30(3):437-446. doi: 10.1101/gr.251686.119. Epub 2020 Feb 19. Genome Res. 2020. PMID: 32075851 Free PMC article.

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Mapping and characterizing N6-methyladenine in eukaryotic genomes using single-molecule real-time sequencing.

Zhu S, Beaulaurier J, Deikus G, Wu TP, Strahl M, Hao Z, Luo G, Gregory JA, Chess A, He C, Xiao A, Sebra R, Schadt EE, Fang G. Zhu S, et al. Among authors: beaulaurier j. Genome Res. 2018 Jul;28(7):1067-1078. doi: 10.1101/gr.231068.117. Epub 2018 May 15. Genome Res. 2018. PMID: 29764913 Free PMC article.

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Interchromosomal template-switching as a novel molecular mechanism for imprinting perturbations associated with Temple syndrome.

Carvalho CMB, Coban-Akdemir Z, Hijazi H, Yuan B, Pendleton M, Harrington E, Beaulaurier J, Juul S, Turner DJ, Kanchi RS, Jhangiani SN, Muzny DM, Gibbs RA; Baylor-Hopkins Center for Mendelian Genomics, Stankiewicz P, Belmont JW, Shaw CA, Cheung SW, Hanchard NA, Sutton VR, Bader PI, Lupski JR. Carvalho CMB, et al. Among authors: beaulaurier j. Genome Med. 2019 Apr 23;11(1):25. doi: 10.1186/s13073-019-0633-y. Genome Med. 2019. PMID: 31014393 Free PMC article.

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Single molecule-level detection and long read-based phasing of epigenetic variations in bacterial methylomes.

Beaulaurier J, Zhang XS, Zhu S, Sebra R, Rosenbluh C, Deikus G, Shen N, Munera D, Waldor MK, Chess A, Blaser MJ, Schadt EE, Fang G. Beaulaurier J, et al. Nat Commun. 2015 Jun 15;6:7438. doi: 10.1038/ncomms8438. Nat Commun. 2015. PMID: 26074426 Free PMC article.

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Susceptibility of Pacific herring to viral hemorrhagic septicemia is influenced by diet.

Beaulaurier J, Bickford N, Gregg JL, Grady CA, Gannam AL, Winton JR, Hershberger PK. Beaulaurier J, et al. J Aquat Anim Health. 2012 Mar;24(1):43-8. doi: 10.1080/08997659.2012.668511. J Aquat Anim Health. 2012. PMID: 22779213 Clinical Trial.

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Evolutionary dynamics of Vibrio cholerae O1 following a single-source introduction to Haiti.

Katz LS, Petkau A, Beaulaurier J, Tyler S, Antonova ES, Turnsek MA, Guo Y, Wang S, Paxinos EE, Orata F, Gladney LM, Stroika S, Folster JP, Rowe L, Freeman MM, Knox N, Frace M, Boncy J, Graham M, Hammer BK, Boucher Y, Bashir A, Hanage WP, Van Domselaar G, Tarr CL. Katz LS, et al. Among authors: beaulaurier j. mBio. 2013 Jul 2;4(4):e00398-13. doi: 10.1128/mBio.00398-13. mBio. 2013. PMID: 23820394 Free PMC article.

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Metagenomic binning and association of plasmids with bacterial host genomes using DNA methylation.

Beaulaurier J, Zhu S, Deikus G, Mogno I, Zhang XS, Davis-Richardson A, Canepa R, Triplett EW, Faith JJ, Sebra R, Schadt EE, Fang G. Beaulaurier J, et al. Nat Biotechnol. 2018 Jan;36(1):61-69. doi: 10.1038/nbt.4037. Epub 2017 Dec 11. Nat Biotechnol. 2018. PMID: 29227468 Free PMC article.

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Identification and validation of genes affecting aortic lesions in mice.

Yang X, Peterson L, Thieringer R, Deignan JL, Wang X, Zhu J, Wang S, Zhong H, Stepaniants S, Beaulaurier J, Wang IM, Rosa R, Cumiskey AM, Luo JM, Luo Q, Shah K, Xiao J, Nickle D, Plump A, Schadt EE, Lusis AJ, Lum PY. Yang X, et al. Among authors: beaulaurier j. J Clin Invest. 2010 Jul;120(7):2414-22. doi: 10.1172/JCI42742. Epub 2010 Jun 23. J Clin Invest. 2010. PMID: 20577049 Free PMC article.

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Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes.

Zhong H, Beaulaurier J, Lum PY, Molony C, Yang X, Macneil DJ, Weingarth DT, Zhang B, Greenawalt D, Dobrin R, Hao K, Woo S, Fabre-Suver C, Qian S, Tota MR, Keller MP, Kendziorski CM, Yandell BS, Castro V, Attie AD, Kaplan LM, Schadt EE. Zhong H, et al. Among authors: beaulaurier j. PLoS Genet. 2010 May 6;6(5):e1000932. doi: 10.1371/journal.pgen.1000932. PLoS Genet. 2010. PMID: 20463879 Free PMC article.

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