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Inducing and exploiting vulnerabilities for the treatment of liver cancer.

Wang C, Vegna S, Jin H, Benedict B, Lieftink C, Ramirez C, de Oliveira RL, Morris B, Gadiot J, Wang W, du Chatinier A, Wang L, Gao D, Evers B, Jin G, Xue Z, Schepers A, Jochems F, Sanchez AM, Mainardi S, Te Riele H, Beijersbergen RL, Qin W, Akkari L, Bernards R. Wang C, et al. Among authors: benedict b. Nature. 2019 Oct;574(7777):268-272. doi: 10.1038/s41586-019-1607-3. Epub 2019 Oct 2. Nature. 2019. PMID: 31578521 Free PMC article.

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Targeting CDC7 potentiates ATR-CHK1 signaling inhibition through induction of DNA replication stress in liver cancer.

Guo Y, Wang J, Benedict B, Yang C, van Gemert F, Ma X, Gao D, Wang H, Zhang S, Lieftink C, Beijersbergen RL, Te Riele H, Qiao X, Gao Q, Sun C, Qin W, Bernards R, Wang C. Guo Y, et al. Among authors: benedict b. Genome Med. 2021 Oct 18;13(1):166. doi: 10.1186/s13073-021-00981-0. Genome Med. 2021. PMID: 34663432 Free PMC article.

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Novel vertebrate- and brain-specific driver of neuronal outgrowth.

Jansen EJR, van Bakel NHM, Benedict B, Olde Loohuis NFM, Hafmans TGM, Chim SM, Xu J, Kolk SM, Martens GJM. Jansen EJR, et al. Among authors: benedict b. Prog Neurobiol. 2021 Jul;202:102069. doi: 10.1016/j.pneurobio.2021.102069. Epub 2021 Apr 29. Prog Neurobiol. 2021. PMID: 33933532 Free article.

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The RECQL helicase prevents replication fork collapse during replication stress.

Benedict B, van Bueren MA, van Gemert FP, Lieftink C, Guerrero Llobet S, van Vugt MA, Beijersbergen RL, Te Riele H. Benedict B, et al. Life Sci Alliance. 2020 Aug 20;3(10):e202000668. doi: 10.26508/lsa.202000668. Print 2020 Oct. Life Sci Alliance. 2020. PMID: 32820027 Free PMC article.

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Effects of Plant Substrate, Insecticide, and Blood Meal Status on the Efficacy of Barrier Treatments Against Aedes albopictus.

McMillan BE, Benedict BL, Brewster CC, Gallagher NT, Paulson SL. McMillan BE, et al. Among authors: benedict bl. J Am Mosq Control Assoc. 2021 Mar 1;37(1):20-27. doi: 10.2987/20-6959. J Am Mosq Control Assoc. 2021. PMID: 33857320 Free article.

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WAPL-Dependent Repair of Damaged DNA Replication Forks Underlies Oncogene-Induced Loss of Sister Chromatid Cohesion.

Benedict B, van Schie JJM, Oostra AB, Balk JA, Wolthuis RMF, Riele HT, de Lange J. Benedict B, et al. Dev Cell. 2020 Mar 23;52(6):683-698.e7. doi: 10.1016/j.devcel.2020.01.024. Epub 2020 Feb 20. Dev Cell. 2020. PMID: 32084359 Free article.

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Loss of p53 suppresses replication-stress-induced DNA breakage in G1/S checkpoint deficient cells.

Benedict B, van Harn T, Dekker M, Hermsen S, Kucukosmanoglu A, Pieters W, Delzenne-Goette E, Dorsman JC, Petermann E, Foijer F, Te Riele H. Benedict B, et al. Elife. 2018 Oct 16;7:e37868. doi: 10.7554/eLife.37868. Elife. 2018. PMID: 30322449 Free PMC article.

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Behavioral deficits and cholinergic pathway abnormalities in male Sanfilippo B mice.

Kan SH, Le SQ, Bui QD, Benedict B, Cushman J, Sands MS, Dickson PI. Kan SH, et al. Among authors: benedict b. Behav Brain Res. 2016 Oct 1;312:265-71. doi: 10.1016/j.bbr.2016.06.023. Epub 2016 Jun 23. Behav Brain Res. 2016. PMID: 27340089 Free PMC article.

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Celastrol-induced degradation of FANCD2 sensitizes pediatric high-grade gliomas to the DNA-crosslinking agent carboplatin.

Metselaar DS, Meel MH, Benedict B, Waranecki P, Koster J, Kaspers GJL, Hulleman E. Metselaar DS, et al. Among authors: benedict b. EBioMedicine. 2019 Dec;50:81-92. doi: 10.1016/j.ebiom.2019.10.062. Epub 2019 Nov 14. EBioMedicine. 2019. PMID: 31735550 Free PMC article.

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AOTA's societal statement on youth violence.

Goertz HD, Benedict B, Bui O, Peitz S, Ryba R, Cahill S; Representative Assembly Coordinating Council. Goertz HD, et al. Among authors: benedict b. Am J Occup Ther. 2008 Nov-Dec;62(6):709-10. doi: 10.5014/ajot.62.6.709. Am J Occup Ther. 2008. PMID: 19024750 No abstract available.

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