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The nucleotide addition cycle of the SARS-CoV-2 polymerase.
Bera SC, Seifert M, Kirchdoerfer RN, van Nies P, Wubulikasimu Y, Quack S, Papini FS, Arnold JJ, Canard B, Cameron CE, Depken M, Dulin D. Bera SC, et al. Cell Rep. 2021 Aug 31;36(9):109650. doi: 10.1016/j.celrep.2021.109650. Epub 2021 Aug 17. Cell Rep. 2021. PMID: 34433083 Free PMC article.
Inhibition of SARS-CoV-2 polymerase by nucleotide analogs: a single molecule perspective.
Seifert M, Bera SC, van Nies P, Kirchdoerfer RN, Shannon A, Le TT, Meng X, Xia H, Wood JM, Harris LD, Papini FS, Arnold JJ, Almo SC, Grove TL, Shi PY, Xiang Y, Canard B, Depken M, Cameron CE, Dulin D. Seifert M, et al. Among authors: bera sc. bioRxiv [Preprint]. 2021 Apr 8:2020.08.06.240325. doi: 10.1101/2020.08.06.240325. bioRxiv. 2021. Update in: Elife. 2021 Oct 07;10:e70968. doi: 10.7554/eLife.70968. PMID: 33851161 Free PMC article. Updated. Preprint.
A post-assembly conformational change makes the SARS-CoV-2 polymerase elongation-competent.
Klein M, Das A, Bera SC, Anderson TK, Kocincova D, Lee HW, Wang B, Papini FS, Marecki JC, Arnold JJ, Cameron CE, Raney KD, Artsimovitch I, Götte M, Kirchdoerfer RN, Depken M, Dulin D. Klein M, et al. Among authors: bera sc. bioRxiv [Preprint]. 2025 Jan 10:2025.01.10.632299. doi: 10.1101/2025.01.10.632299. bioRxiv. 2025. PMID: 39829827 Free PMC article. Preprint.
27 results