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GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human β cell regeneration.
Ackeifi C, Wang P, Karakose E, Manning Fox JE, González BJ, Liu H, Wilson J, Swartz E, Berrouet C, Li Y, Kumar K, MacDonald PE, Sanchez R, Thorens B, DeVita R, Homann D, Egli D, Scott DK, Garcia-Ocaña A, Stewart AF. Ackeifi C, et al. Among authors: berrouet c. Sci Transl Med. 2020 Feb 12;12(530):eaaw9996. doi: 10.1126/scitranslmed.aaw9996. Sci Transl Med. 2020. PMID: 32051230 Free PMC article.
Synthesis and Biological Validation of a Harmine-Based, Central Nervous System (CNS)-Avoidant, Selective, Human β-Cell Regenerative Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase A (DYRK1A) Inhibitor.
Kumar K, Wang P, Wilson J, Zlatanic V, Berrouet C, Khamrui S, Secor C, Swartz EA, Lazarus M, Sanchez R, Stewart AF, Garcia-Ocana A, DeVita RJ. Kumar K, et al. Among authors: berrouet c. J Med Chem. 2020 Mar 26;63(6):2986-3003. doi: 10.1021/acs.jmedchem.9b01379. Epub 2020 Feb 19. J Med Chem. 2020. PMID: 32003560 Free PMC article.
Production of native and modified recombinant Der p 1 molecules in tobacco plants.
Burtin D, Chabre H, Olagnier B, Didierlaurent A, Couret MN, Comeau D, Wambre E, Laparra H, Van Overtvelt L, Montandon F, Batard T, Jonval V, Lorphelin A, Merle C, Berrouet C, Parry L, Gomord V, Van Ree R, Moingeon P. Burtin D, et al. Among authors: berrouet c. Clin Exp Allergy. 2009 May;39(5):760-70. doi: 10.1111/j.1365-2222.2009.03201.x. Epub 2009 Feb 18. Clin Exp Allergy. 2009. PMID: 19226276
Recombinant fusion proteins assembling Der p 1 and Der p 2 allergens from Dermatophagoides pteronyssinus.
Bussières L, Bordas-Le Floch V, Bulder I, Chabre H, Nony E, Lautrette A, Berrouet C, Nguefeu Y, Horiot S, Baron-Bodo V, Van Overtvelt L, De Conti AM, Schlegel A, Maguet N, Mouz N, Lemoine P, Batard T, Moingeon P. Bussières L, et al. Among authors: berrouet c. Int Arch Allergy Immunol. 2010;153(2):141-51. doi: 10.1159/000312631. Epub 2010 Apr 21. Int Arch Allergy Immunol. 2010. PMID: 20407270