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A p53-TLR3 axis ameliorates pulmonary hypertension by inducing BMPR2 via IRF3.
Bhagwani AR, Ali M, Piper B, Liu M, Hudson J, Kelly N, Bogamuwa S, Yang H, Londino JD, Bednash JS, Farkas D, Mallampalli RK, Nicolls MR, Ryan JJ, Thompson AAR, Chan SY, Gomez D, Goncharova EA, Farkas L. Bhagwani AR, et al. iScience. 2023 Jan 5;26(2):105935. doi: 10.1016/j.isci.2023.105935. eCollection 2023 Feb 17. iScience. 2023. PMID: 36685041 Free PMC article.
RAB7 deficiency impairs pulmonary artery endothelial function and promotes pulmonary hypertension.
Piper B, Bogamuwa S, Hossain T, Farkas D, Rosas L, Green A, Newcomb G, Sun N, Horowitz JC, Bhagwani AR, Yang H, Kudryashova TV, Rojas M, Mora AL, Yan P, Mallampalli RK, Goncharova EA, Eckmann DM, Farkas L. Piper B, et al. Among authors: bhagwani ar. bioRxiv. 2023 Feb 6:2023.02.03.526842. doi: 10.1101/2023.02.03.526842. Preprint. bioRxiv. 2023. PMID: 36778418 Free PMC article.
Toll-like Receptor 3 Is a Therapeutic Target for Pulmonary Hypertension.
Farkas D, Thompson AAR, Bhagwani AR, Hultman S, Ji H, Kotha N, Farr G, Arnold ND, Braithwaite A, Casbolt H, Cole JE, Sabroe I, Monaco C, Cool CD, Goncharova EA, Lawrie A, Farkas L. Farkas D, et al. Among authors: bhagwani ar. Am J Respir Crit Care Med. 2019 Jan 15;199(2):199-210. doi: 10.1164/rccm.201707-1370OC. Am J Respir Crit Care Med. 2019. PMID: 30211629 Free PMC article.