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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1983 1
1984 1
1986 1
1988 1
1989 1
1990 1
1991 2
1992 3
1993 1
1994 5
1995 1
1996 2
1999 1
2002 1
2005 1
2006 1
2007 3
2008 3
2009 2
2010 4
2011 3
2012 1
2014 1
2022 0
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40 results
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Page 1
Discovery of TRPV1 antagonist ABT-116.
Brown BS, Keddy R, Perner RJ, DiDomenico S, Koenig JR, Jinkerson TK, Hannick SM, McDonald HA, Bianchi BR, Honore P, Puttfarcken PS, Moreland RB, Marsh KC, Faltynek CR, Lee CH. Brown BS, et al. Among authors: bianchi br. Bioorg Med Chem Lett. 2010 Jun 1;20(11):3291-4. doi: 10.1016/j.bmcl.2010.04.047. Epub 2010 Apr 14. Bioorg Med Chem Lett. 2010. PMID: 20457518
Chroman and tetrahydroquinoline ureas as potent TRPV1 antagonists.
Schmidt RG, Bayburt EK, Latshaw SP, Koenig JR, Daanen JF, McDonald HA, Bianchi BR, Zhong C, Joshi S, Honore P, Marsh KC, Lee CH, Faltynek CR, Gomtsyan A. Schmidt RG, et al. Among authors: bianchi br. Bioorg Med Chem Lett. 2011 Mar 1;21(5):1338-41. doi: 10.1016/j.bmcl.2011.01.056. Epub 2011 Jan 21. Bioorg Med Chem Lett. 2011. PMID: 21315587
Discovery of (R)-1-(7-chloro-2,2-bis(fluoromethyl)chroman-4-yl)-3-(3-methylisoquinolin-5-yl)urea (A-1165442): a temperature-neutral transient receptor potential vanilloid-1 (TRPV1) antagonist with analgesic efficacy.
Voight EA, Gomtsyan AR, Daanen JF, Perner RJ, Schmidt RG, Bayburt EK, DiDomenico S, McDonald HA, Puttfarcken PS, Chen J, Neelands TR, Bianchi BR, Han P, Reilly RM, Franklin PH, Segreti JA, Nelson RA, Su Z, King AJ, Polakowski JS, Baker SJ, Gauvin DM, Lewis LR, Mikusa JP, Joshi SK, Faltynek CR, Kym PR, Kort ME. Voight EA, et al. Among authors: bianchi br. J Med Chem. 2014 Sep 11;57(17):7412-24. doi: 10.1021/jm500916t. Epub 2014 Aug 21. J Med Chem. 2014. PMID: 25100568
Development of ELISA to measure TRPV1 protein in rat tissues.
Han P, Korepanova AV, Vos MH, Pereda-Lopez A, Lake MR, Bianchi BR, Moreland RB, Faltynek CR, Chiu ML. Han P, et al. Among authors: bianchi br. J Neurosci Methods. 2011 Sep 15;200(2):144-52. doi: 10.1016/j.jneumeth.2011.06.029. Epub 2011 Jul 6. J Neurosci Methods. 2011. PMID: 21762727
Pore dilation occurs in TRPA1 but not in TRPM8 channels.
Chen J, Kim D, Bianchi BR, Cavanaugh EJ, Faltynek CR, Kym PR, Reilly RM. Chen J, et al. Among authors: bianchi br. Mol Pain. 2009 Jan 21;5:3. doi: 10.1186/1744-8069-5-3. Mol Pain. 2009. PMID: 19159452 Free PMC article.
Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation.
Chen J, Joshi SK, DiDomenico S, Perner RJ, Mikusa JP, Gauvin DM, Segreti JA, Han P, Zhang XF, Niforatos W, Bianchi BR, Baker SJ, Zhong C, Simler GH, McDonald HA, Schmidt RG, McGaraughty SP, Chu KL, Faltynek CR, Kort ME, Reilly RM, Kym PR. Chen J, et al. Among authors: bianchi br. Pain. 2011 May;152(5):1165-1172. doi: 10.1016/j.pain.2011.01.049. Epub 2011 Mar 12. Pain. 2011. PMID: 21402443
40 results