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54 results

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Page 1
The SWI/SNF chromatin-remodeling subunit DPF2 facilitates NRF2-dependent antiinflammatory and antioxidant gene expression.
Mas G, Man N, Nakata Y, Martinez-Caja C, Karl D, Beckedorff F, Tamiro F, Chen C, Duffort S, Itonaga H, Mookhtiar AK, Kunkalla K, Valencia AM, Collings CK, Kadoch C, Vega F, Kogan SC, Shiekhattar R, Morey L, Bilbao D, Nimer SD. Mas G, et al. Among authors: bilbao d. J Clin Invest. 2023 Jul 3;133(13):e158419. doi: 10.1172/JCI158419. J Clin Invest. 2023. PMID: 37200093 Free PMC article.
Tyrosine phosphorylation of CARM1 promotes its enzymatic activity and alters its target specificity.
Itonaga H, Mookhtiar AK, Greenblatt SM, Liu F, Martinez C, Bilbao D, Rains M, Hamard PJ, Sun J, Umeano AC, Duffort S, Chen C, Man N, Mas G, Tottone L, Totiger T, Bradley T, Taylor J, Schürer S, Nimer SD. Itonaga H, et al. Among authors: bilbao d. Nat Commun. 2024 Apr 22;15(1):3415. doi: 10.1038/s41467-024-47689-4. Nat Commun. 2024. PMID: 38649367 Free PMC article.
Endocrine resistance and breast cancer plasticity are controlled by CoREST.
Garcia-Martinez L, Adams AM, Chan HL, Nakata Y, Weich N, Stransky S, Zhang Z, Alshalalfa M, Sarria L, Mahal BA, Kesmodel SB, Celià-Terrassa T, Liu Z, Minucci S, Bilbao D, Sidoli S, Verdun RE, Morey L. Garcia-Martinez L, et al. Among authors: bilbao d. Nat Struct Mol Biol. 2022 Nov;29(11):1122-1135. doi: 10.1038/s41594-022-00856-x. Epub 2022 Nov 7. Nat Struct Mol Biol. 2022. PMID: 36344844 Free PMC article.
Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition.
Chaudhry S, Beckedorff F, Jasdanwala SS, Totiger TM, Affer M, Lawal AE, Montoya S, Tamiro F, Tonini O, Chirino A, Adams A, Sondhi AK, Noudali S, Cornista AM, Nicholls M, Afaghani J, Robayo P, Bilbao D, Nimer SD, Rodríguez JA, Bhatt S, Wang E, Taylor J. Chaudhry S, et al. Among authors: bilbao d. Leukemia. 2024 Sep;38(9):1894-1905. doi: 10.1038/s41375-024-02328-1. Epub 2024 Jul 13. Leukemia. 2024. PMID: 38997434 Free PMC article.
Post-stroke hippocampal neurogenesis is impaired by microvascular dysfunction and PI3K signaling in cerebral amyloid angiopathy.
Osborne OM, Daftari M, Naranjo O, Johar AN, Brooks S, Colbert BM, Torices S, Lewis E, Sendaydiego J, Drexler G, Bashti M, Margetts AV, Tuesta LM, Mason C, Bilbao D, Vontell R, Griswold AJ, Dykxhoorn DM, Toborek M. Osborne OM, et al. Among authors: bilbao d. Cell Rep. 2024 Oct 22;43(10):114848. doi: 10.1016/j.celrep.2024.114848. Epub 2024 Oct 10. Cell Rep. 2024. PMID: 39392753 Free PMC article.
Methylation of histone H3 lysine 36 is a barrier for therapeutic interventions of head and neck squamous cell carcinoma.
Caeiro LD, Nakata Y, Borges RL, Zha M, Garcia-Martinez L, Bañuelos CP, Stransky S, Liu T, Chan HL, Brabson J, Domínguez D, Zhang Y, Lewis PW, Aznar Benitah S, Cimmino L, Bilbao D, Sidoli S, Wang Z, Verdun RE, Morey L. Caeiro LD, et al. Among authors: bilbao d. Genes Dev. 2024 Feb 13;38(1-2):46-69. doi: 10.1101/gad.351408.123. Genes Dev. 2024. PMID: 38286657 Free PMC article.
Methylation of histone H3 lysine 36 is a barrier for therapeutic interventions of head and neck squamous cell carcinoma.
Caeiro LD, Nakata Y, Borges RL, Garcia-Martinez L, Bañuelos CP, Stransky S, Chan HL, Brabson J, Domínguez D, Zhang Y, Lewis PW, Aznar-Benitah S, Cimmino L, Bilbao D, Sidoli S, Verdun RE, Morey L. Caeiro LD, et al. Among authors: bilbao d. bioRxiv [Preprint]. 2023 Nov 6:2023.11.06.565847. doi: 10.1101/2023.11.06.565847. bioRxiv. 2023. Update in: Genes Dev. 2024 Feb 13;38(1-2):46-69. doi: 10.1101/gad.351408.123 PMID: 38076924 Free PMC article. Updated. Preprint.
Aminopyridine analogs selectively target metastatic pancreatic cancer.
Smalling RV, Bechard ME, Duryea J, Kingsley PJ, Roberts ER, Marnett LJ, Bilbao D, Stauffer SR, McDonald OG. Smalling RV, et al. Among authors: bilbao d. Oncogene. 2022 Mar;41(10):1518-1525. doi: 10.1038/s41388-022-02183-3. Epub 2022 Jan 14. Oncogene. 2022. PMID: 35031771 Free PMC article.
Oxidized mC modulates synthetic lethality to PARP inhibitors for the treatment of leukemia.
Brabson JP, Leesang T, Yap YS, Wang J, Lam MQ, Fang B, Dolgalev I, Barbieri DA, Strippoli V, Bañuelos CP, Mohammad S, Lyon P, Chaudhry S, Donich D, Swirski A, Roberts E, Diaz I, Karl D, Dos Santos HG, Shiekhattar R, Neel BG, Nimer SD, Verdun RE, Bilbao D, Figueroa ME, Cimmino L. Brabson JP, et al. Among authors: bilbao d. Cell Rep. 2023 Jan 31;42(1):112027. doi: 10.1016/j.celrep.2023.112027. Epub 2023 Jan 23. Cell Rep. 2023. PMID: 36848231 Free PMC article.
Smoking induces WEE1 expression to promote docetaxel resistance in esophageal adenocarcinoma.
Islam MO, Thangaretnam K, Lu H, Peng D, Soutto M, El-Rifai W, Giordano S, Ban Y, Chen X, Bilbao D, Villarino AV, Schürer S, Hosein PJ, Chen Z. Islam MO, et al. Among authors: bilbao d. Mol Ther Oncolytics. 2023 Aug 28;30:286-300. doi: 10.1016/j.omto.2023.08.012. eCollection 2023 Sep 21. Mol Ther Oncolytics. 2023. PMID: 37732296 Free PMC article.
54 results