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Chromothripsis as an on-target consequence of CRISPR-Cas9 genome editing.
Leibowitz ML, Papathanasiou S, Doerfler PA, Blaine LJ, Sun L, Yao Y, Zhang CZ, Weiss MJ, Pellman D. Leibowitz ML, et al. Among authors: blaine lj. Nat Genet. 2021 Jun;53(6):895-905. doi: 10.1038/s41588-021-00838-7. Epub 2021 Apr 12. Nat Genet. 2021. PMID: 33846636 Free PMC article.
Mechanisms generating cancer genome complexity from a single cell division error.
Umbreit NT, Zhang CZ, Lynch LD, Blaine LJ, Cheng AM, Tourdot R, Sun L, Almubarak HF, Judge K, Mitchell TJ, Spektor A, Pellman D. Umbreit NT, et al. Among authors: blaine lj. Science. 2020 Apr 17;368(6488):eaba0712. doi: 10.1126/science.aba0712. Science. 2020. PMID: 32299917 Free PMC article.