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Year Number of Results
2004 2
2005 1
2006 2
2009 1
2013 2
2015 1
2016 1
2019 2
2021 0
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12 results
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Page 1
Stable pantothenamide bioisosteres: novel antibiotics for Gram-positive bacteria.
Jansen PAM, van der Krieken DA, Botman PNM, Blaauw RH, Cavina L, Raaijmakers EM, de Heuvel E, Sandrock J, Pennings LJ, Hermkens PHH, Zeeuwen PLJM, Rutjes FPJT, Schalkwijk J. Jansen PAM, et al. Among authors: botman pnm. J Antibiot (Tokyo). 2019 Sep;72(9):682-692. doi: 10.1038/s41429-019-0196-6. Epub 2019 Jun 6. J Antibiot (Tokyo). 2019. PMID: 31171848 Free PMC article.
Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in Plasmodium falciparum.
Schalkwijk J, Allman EL, Jansen PAM, de Vries LE, Verhoef JMJ, Jackowski S, Botman PNM, Beuckens-Schortinghuis CA, Koolen KMJ, Bolscher JM, Vos MW, Miller K, Reeves SA, Pett H, Trevitt G, Wittlin S, Scheurer C, Sax S, Fischli C, Angulo-Barturen I, Jiménez-Diaz MB, Josling G, Kooij TWA, Bonnert R, Campo B, Blaauw RH, Rutjes FPJT, Sauerwein RW, Llinás M, Hermkens PHH, Dechering KJ. Schalkwijk J, et al. Among authors: botman pnm. Sci Transl Med. 2019 Sep 18;11(510):eaas9917. doi: 10.1126/scitranslmed.aas9917. Sci Transl Med. 2019. PMID: 31534021
Novel pantothenate derivatives for anti-malarial chemotherapy.
Pett HE, Jansen PA, Hermkens PH, Botman PN, Beuckens-Schortinghuis CA, Blaauw RH, Graumans W, van de Vegte-Bolmer M, Koolen KM, Rutjes FP, Dechering KJ, Sauerwein RW, Schalkwijk J. Pett HE, et al. Among authors: botman pn. Malar J. 2015 Apr 18;14:169. doi: 10.1186/s12936-015-0673-8. Malar J. 2015. PMID: 25927675 Free PMC article.
Discovery of small molecule vanin inhibitors: new tools to study metabolism and disease.
Jansen PA, van Diepen JA, Ritzen B, Zeeuwen PL, Cacciatore I, Cornacchia C, van Vlijmen-Willems IM, de Heuvel E, Botman PN, Blaauw RH, Hermkens PH, Rutjes FP, Schalkwijk J. Jansen PA, et al. Among authors: botman pn. ACS Chem Biol. 2013 Mar 15;8(3):530-4. doi: 10.1021/cb3006424. Epub 2013 Jan 2. ACS Chem Biol. 2013. PMID: 23270378
Total synthesis of (+)-epiquinamide.
Wijdeven MA, Botman PN, Wijtmans R, Schoemaker HE, Rutjes FP, Blaauw RH. Wijdeven MA, et al. Among authors: botman pn. Org Lett. 2005 Sep 1;7(18):4005-7. doi: 10.1021/ol0515715. Org Lett. 2005. PMID: 16119953
Complementary chemoenzymatic routes to both enantiomers of febrifugine.
Wijdeven MA, van den Berg RJ, Wijtmans R, Botman PN, Blaauw RH, Schoemaker HE, van Delft FL, Rutjes FP. Wijdeven MA, et al. Among authors: botman pn. Org Biomol Chem. 2009 Jul 21;7(14):2976-80. doi: 10.1039/b901670h. Epub 2009 Jun 4. Org Biomol Chem. 2009. PMID: 19582308
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