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Model-based prediction of effective target exposure for MEN1611 in combination with trastuzumab in HER2-positive advanced or metastatic breast cancer patients.
Tosca EM, Borella E, Piana C, Bouchene S, Merlino G, Fiascarelli A, Mazzei P, Magni P. Tosca EM, et al. Among authors: bouchene s. CPT Pharmacometrics Syst Pharmacol. 2023 Nov;12(11):1626-1639. doi: 10.1002/psp4.12910. Epub 2023 Feb 15. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 36793223 Free PMC article.
A non-linear mixed effect model for innate immune response: In vivo kinetics of endotoxin and its induction of the cytokines tumor necrosis factor alpha and interleukin-6.
Thorsted A, Bouchene S, Tano E, Castegren M, Lipcsey M, Sjölin J, Karlsson MO, Friberg LE, Nielsen EI. Thorsted A, et al. Among authors: bouchene s. PLoS One. 2019 Feb 21;14(2):e0211981. doi: 10.1371/journal.pone.0211981. eCollection 2019. PLoS One. 2019. PMID: 30789941 Free PMC article.