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Inhibitors of acyl-CoA: cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. CI-1011: an acyl sulfamate with unique cholesterol-lowering activity in animals fed noncholesterol-supplemented diets.
Lee HT, Sliskovic DR, Picard JA, Roth BD, Wierenga W, Hicks JL, Bousley RF, Hamelehle KL, Homan R, Speyer C, Stanfield RL, Krause BR. Lee HT, et al. Among authors: bousley rf. J Med Chem. 1996 Dec 20;39(26):5031-4. doi: 10.1021/jm960674d. J Med Chem. 1996. PMID: 8978833 No abstract available.
Substituted oxazolidinones as novel NPC1L1 ligands for the inhibition of cholesterol absorption.
Pfefferkorn JA, Larsen SD, Van Huis C, Sorenson R, Barton T, Winters T, Auerbach B, Wu C, Wolfram TJ, Cai H, Welch K, Esmaiel N, Davis J, Bousley R, Olsen K, Mueller SB, Mertz T. Pfefferkorn JA, et al. Among authors: bousley r. Bioorg Med Chem Lett. 2008 Jan 15;18(2):546-53. doi: 10.1016/j.bmcl.2007.11.083. Epub 2007 Nov 28. Bioorg Med Chem Lett. 2008. PMID: 18063367
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