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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1950 1
1951 1
1954 4
1955 1
1957 1
1958 2
1960 2
1961 2
1962 1
1963 4
1964 8
1965 8
1966 7
1967 2
1968 6
1969 4
1970 7
1971 6
1972 16
1973 5
1974 1
1975 5
1976 5
1977 8
1978 4
1979 7
1980 6
1981 13
1982 9
1983 9
1984 12
1985 4
1986 10
1987 23
1988 14
1989 14
1990 17
1991 16
1992 14
1993 11
1994 10
1995 18
1996 16
1997 10
1998 13
1999 7
2000 10
2001 14
2002 18
2003 16
2004 22
2005 22
2006 17
2007 22
2008 12
2009 10
2010 19
2011 17
2012 17
2013 16
2014 15
2015 11
2016 18
2017 24
2018 22
2019 27
2020 20
2021 30
2022 31
2023 2
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Search Results

761 results
Results by year
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Page 1
Community guidelines for GPCR ligand bias: IUPHAR review 32.
Kolb P, Kenakin T, Alexander SPH, Bermudez M, Bohn LM, Breinholt CS, Bouvier M, Hill SJ, Kostenis E, Martemyanov KA, Neubig RR, Onaran HO, Rajagopal S, Roth BL, Selent J, Shukla AK, Sommer ME, Gloriam DE. Kolb P, et al. Among authors: bouvier m. Br J Pharmacol. 2022 Jul;179(14):3651-3674. doi: 10.1111/bph.15811. Epub 2022 Mar 27. Br J Pharmacol. 2022. PMID: 35106752 Free PMC article. Review.
Structure-based discovery of nonopioid analgesics acting through the α2A-adrenergic receptor.
Fink EA, Xu J, Hübner H, Braz JM, Seemann P, Avet C, Craik V, Weikert D, Schmidt MF, Webb CM, Tolmachova NA, Moroz YS, Huang XP, Kalyanaraman C, Gahbauer S, Chen G, Liu Z, Jacobson MP, Irwin JJ, Bouvier M, Du Y, Shoichet BK, Basbaum AI, Gmeiner P. Fink EA, et al. Among authors: bouvier m. Science. 2022 Sep 30;377(6614):eabn7065. doi: 10.1126/science.abn7065. Epub 2022 Sep 30. Science. 2022. PMID: 36173843
How GPCR Phosphorylation Patterns Orchestrate Arrestin-Mediated Signaling.
Latorraca NR, Masureel M, Hollingsworth SA, Heydenreich FM, Suomivuori CM, Brinton C, Townshend RJL, Bouvier M, Kobilka BK, Dror RO. Latorraca NR, et al. Among authors: bouvier m. Cell. 2020 Dec 23;183(7):1813-1825.e18. doi: 10.1016/j.cell.2020.11.014. Epub 2020 Dec 8. Cell. 2020. PMID: 33296703 Free PMC article.
GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling.
Thomsen ARB, Plouffe B, Cahill TJ 3rd, Shukla AK, Tarrasch JT, Dosey AM, Kahsai AW, Strachan RT, Pani B, Mahoney JP, Huang L, Breton B, Heydenreich FM, Sunahara RK, Skiniotis G, Bouvier M, Lefkowitz RJ. Thomsen ARB, et al. Among authors: bouvier m. Cell. 2016 Aug 11;166(4):907-919. doi: 10.1016/j.cell.2016.07.004. Epub 2016 Aug 4. Cell. 2016. PMID: 27499021 Free PMC article.
Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs.
Avet C, Mancini A, Breton B, Le Gouill C, Hauser AS, Normand C, Kobayashi H, Gross F, Hogue M, Lukasheva V, St-Onge S, Carrier M, Héroux M, Morissette S, Fauman EB, Fortin JP, Schann S, Leroy X, Gloriam DE, Bouvier M. Avet C, et al. Among authors: bouvier m. Elife. 2022 Mar 18;11:e74101. doi: 10.7554/eLife.74101. Elife. 2022. PMID: 35302493 Free PMC article.
GPCR activation mechanisms across classes and macro/microscales.
Hauser AS, Kooistra AJ, Munk C, Heydenreich FM, Veprintsev DB, Bouvier M, Babu MM, Gloriam DE. Hauser AS, et al. Among authors: bouvier m. Nat Struct Mol Biol. 2021 Nov;28(11):879-888. doi: 10.1038/s41594-021-00674-7. Epub 2021 Nov 10. Nat Struct Mol Biol. 2021. PMID: 34759375 Free PMC article.
Discovery of a dual Ras and ARF6 inhibitor from a GPCR endocytosis screen.
Giubilaro J, Schuetz DA, Stepniewski TM, Namkung Y, Khoury E, Lara-Márquez M, Campbell S, Beautrait A, Armando S, Radresa O, Duchaine J, Lamarche-Vane N, Claing A, Selent J, Bouvier M, Marinier A, Laporte SA. Giubilaro J, et al. Among authors: bouvier m. Nat Commun. 2021 Aug 3;12(1):4688. doi: 10.1038/s41467-021-24968-y. Nat Commun. 2021. PMID: 34344896 Free PMC article.
BRET-based effector membrane translocation assay monitors GPCR-promoted and endocytosis-mediated Gq activation at early endosomes.
Wright SC, Lukasheva V, Le Gouill C, Kobayashi H, Breton B, Mailhot-Larouche S, Blondel-Tepaz É, Antunes Vieira N, Costa-Neto C, Héroux M, Lambert NA, Parreiras-E-Silva LT, Bouvier M. Wright SC, et al. Among authors: bouvier m. Proc Natl Acad Sci U S A. 2021 May 18;118(20):e2025846118. doi: 10.1073/pnas.2025846118. Proc Natl Acad Sci U S A. 2021. PMID: 33990469 Free PMC article.
Common coupling map advances GPCR-G protein selectivity.
Hauser AS, Avet C, Normand C, Mancini A, Inoue A, Bouvier M, Gloriam DE. Hauser AS, et al. Among authors: bouvier m. Elife. 2022 Mar 18;11:e74107. doi: 10.7554/eLife.74107. Elife. 2022. PMID: 35302494 Free PMC article.
761 results