Search Page

1

Cite

Share

Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'.

Levin AM, Bates DL, Ring AM, Krieg C, Lin JT, Su L, Moraga I, Raeber ME, Bowman GR, Novick P, Pande VS, Fathman CG, Boyman O, Garcia KC. Levin AM, et al. Among authors: bowman gr. Nature. 2012 Mar 25;484(7395):529-33. doi: 10.1038/nature10975. Nature. 2012. PMID: 22446627 Free PMC article.

Cite

Share

2

Cite

Share

Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15.

Ring AM, Lin JX, Feng D, Mitra S, Rickert M, Bowman GR, Pande VS, Li P, Moraga I, Spolski R, Ozkan E, Leonard WJ, Garcia KC. Ring AM, et al. Among authors: bowman gr. Nat Immunol. 2012 Dec;13(12):1187-95. doi: 10.1038/ni.2449. Epub 2012 Oct 28. Nat Immunol. 2012. PMID: 23104097 Free PMC article.

Cite

Share

3

Cite

Share

The Cap-Snatching SFTSV Endonuclease Domain Is an Antiviral Target.

Wang W, Shin WJ, Zhang B, Choi Y, Yoo JS, Zimmerman MI, Frederick TE, Bowman GR, Gross ML, Leung DW, Jung JU, Amarasinghe GK. Wang W, et al. Among authors: bowman gr. Cell Rep. 2020 Jan 7;30(1):153-163.e5. doi: 10.1016/j.celrep.2019.12.020. Cell Rep. 2020. PMID: 31914382 Free PMC article.

Cite

Share

4

Cite

Share

The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA.

Cubuk J, Alston JJ, Incicco JJ, Singh S, Stuchell-Brereton MD, Ward MD, Zimmerman MI, Vithani N, Griffith D, Wagoner JA, Bowman GR, Hall KB, Soranno A, Holehouse AS. Cubuk J, et al. Among authors: bowman gr. bioRxiv. 2020 Jun 18:2020.06.17.158121. doi: 10.1101/2020.06.17.158121. Preprint. bioRxiv. 2020. PMID: 32587966 Free PMC article. Updated.

Cite

Share

5

Cite

Share

Investigating Cryptic Binding Sites by Molecular Dynamics Simulations.

Kuzmanic A, Bowman GR, Juarez-Jimenez J, Michel J, Gervasio FL. Kuzmanic A, et al. Among authors: bowman gr. Acc Chem Res. 2020 Mar 17;53(3):654-661. doi: 10.1021/acs.accounts.9b00613. Epub 2020 Mar 5. Acc Chem Res. 2020. PMID: 32134250 Free PMC article. Review.

Cite

Share

6

Cite

Share

Everything you wanted to know about Markov State Models but were afraid to ask.

Pande VS, Beauchamp K, Bowman GR. Pande VS, et al. Among authors: bowman gr. Methods. 2010 Sep;52(1):99-105. doi: 10.1016/j.ymeth.2010.06.002. Epub 2010 Jun 4. Methods. 2010. PMID: 20570730 Free PMC article. Review.

Cite

Share

7

Cite

Share

How to Run FAST Simulations.

Zimmerman MI, Bowman GR. Zimmerman MI, et al. Among authors: bowman gr. Methods Enzymol. 2016;578:213-25. doi: 10.1016/bs.mie.2016.05.032. Epub 2016 Jun 16. Methods Enzymol. 2016. PMID: 27497168 Review.

Cite

Share

8

Cite

Share

Citizen Scientists Create an Exascale Computer to Combat COVID-19.

Zimmerman MI, Porter JR, Ward MD, Singh S, Vithani N, Meller A, Mallimadugula UL, Kuhn CE, Borowsky JH, Wiewiora RP, Hurley MFD, Harbison AM, Fogarty CA, Coffland JE, Fadda E, Voelz VA, Chodera JD, Bowman GR. Zimmerman MI, et al. Among authors: bowman gr. bioRxiv. 2020 Jun 28:2020.06.27.175430. doi: 10.1101/2020.06.27.175430. Preprint. bioRxiv. 2020. PMID: 32637963 Free PMC article.

Cite

Share

9

Cite

Share

Inducible asymmetric cell division and cell differentiation in a bacterium.

Mushnikov NV, Fomicheva A, Gomelsky M, Bowman GR. Mushnikov NV, et al. Among authors: bowman gr. Nat Chem Biol. 2019 Sep;15(9):925-931. doi: 10.1038/s41589-019-0340-4. Epub 2019 Aug 12. Nat Chem Biol. 2019. PMID: 31406376 Free PMC article.

Cite

Share

10

Cite

Share

Advanced Methods for Accessing Protein Shape-Shifting Present New Therapeutic Opportunities.

Knoverek CR, Amarasinghe GK, Bowman GR. Knoverek CR, et al. Among authors: bowman gr. Trends Biochem Sci. 2019 Apr;44(4):351-364. doi: 10.1016/j.tibs.2018.11.007. Epub 2018 Dec 14. Trends Biochem Sci. 2019. PMID: 30555007 Free PMC article. Review.

Cite

Share