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Structure-based discovery of conformationally selective inhibitors of the serotonin transporter.
Singh I, Seth A, Billesbølle CB, Braz J, Rodriguiz RM, Roy K, Bekele B, Craik V, Huang XP, Boytsov D, Pogorelov VM, Lak P, O'Donnell H, Sandtner W, Irwin JJ, Roth BL, Basbaum AI, Wetsel WC, Manglik A, Shoichet BK, Rudnick G. Singh I, et al. Among authors: boytsov d. Cell. 2023 May 11;186(10):2160-2175.e17. doi: 10.1016/j.cell.2023.04.010. Epub 2023 May 2. Cell. 2023. PMID: 37137306 Free PMC article.
Optimizing the Substrate Uptake Rate of Solute Carriers.
Schicker K, Farr CV, Boytsov D, Freissmuth M, Sandtner W. Schicker K, et al. Among authors: boytsov d. Front Physiol. 2022 Feb 3;13:817886. doi: 10.3389/fphys.2022.817886. eCollection 2022. Front Physiol. 2022. PMID: 35185619 Free PMC article.
A mechanism of uncompetitive inhibition of the serotonin transporter.
Bhat S, El-Kasaby A, Kasture A, Boytsov D, Reichelt JB, Hummel T, Sucic S, Pifl C, Freissmuth M, Sandtner W. Bhat S, et al. Among authors: boytsov d. Elife. 2023 Jan 17;12:e82641. doi: 10.7554/eLife.82641. Elife. 2023. PMID: 36648438 Free PMC article.
Photoswitching of model ion channels in lipid bilayers.
Pfeffermann J, Eicher B, Boytsov D, Hannesschlaeger C, Galimzyanov TR, Glasnov TN, Pabst G, Akimov SA, Pohl P. Pfeffermann J, et al. Among authors: boytsov d. J Photochem Photobiol B. 2021 Nov;224:112320. doi: 10.1016/j.jphotobiol.2021.112320. Epub 2021 Sep 22. J Photochem Photobiol B. 2021. PMID: 34600201 Free article.
Trapped Pore Waters in the Open Proton Channel HV 1.
Boytsov D, Brescia S, Chaves G, Koefler S, Hannesschlaeger C, Siligan C, Goessweiner-Mohr N, Musset B, Pohl P. Boytsov D, et al. Small. 2023 Apr;19(16):e2205968. doi: 10.1002/smll.202205968. Epub 2023 Jan 22. Small. 2023. PMID: 36683221
Identification of the potassium-binding site in serotonin transporter.
Hellsberg E, Boytsov D, Chen Q, Niello M, Freissmuth M, Rudnick G, Zhang YW, Sandtner W, Forrest LR. Hellsberg E, et al. Among authors: boytsov d. Proc Natl Acad Sci U S A. 2024 Apr 30;121(18):e2319384121. doi: 10.1073/pnas.2319384121. Epub 2024 Apr 23. Proc Natl Acad Sci U S A. 2024. PMID: 38652746 Free PMC article.
12 results