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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
1976 3
1977 1
1978 6
1980 4
1981 2
1982 4
1983 2
1984 1
1985 4
1986 3
1987 4
1988 6
1989 4
1990 5
1991 10
1992 10
1993 2
1994 5
1995 2
1996 4
1997 4
1998 4
1999 4
2000 6
2001 8
2002 14
2003 5
2004 5
2005 6
2006 11
2007 15
2008 11
2009 7
2010 6
2011 7
2012 6
2013 9
2014 6
2015 2
2016 2
2017 8
2018 6
2019 7
2020 7
2021 1
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Search Results

230 results
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Page 1
Selective PP2A Enhancement through Biased Heterotrimer Stabilization.
Leonard D, Huang W, Izadmehr S, O'Connor CM, Wiredja DD, Wang Z, Zaware N, Chen Y, Schlatzer DM, Kiselar J, Vasireddi N, Schüchner S, Perl AL, Galsky MD, Xu W, Brautigan DL, Ogris E, Taylor DJ, Narla G. Leonard D, et al. Among authors: brautigan dl. Cell. 2020 Apr 30;181(3):688-701.e16. doi: 10.1016/j.cell.2020.03.038. Epub 2020 Apr 20. Cell. 2020. PMID: 32315618 Free PMC article.
Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth.
Sangodkar J, Perl A, Tohme R, Kiselar J, Kastrinsky DB, Zaware N, Izadmehr S, Mazhar S, Wiredja DD, O'Connor CM, Hoon D, Dhawan NS, Schlatzer D, Yao S, Leonard D, Borczuk AC, Gokulrangan G, Wang L, Svenson E, Farrington CC, Yuan E, Avelar RA, Stachnik A, Smith B, Gidwani V, Giannini HM, McQuaid D, McClinch K, Wang Z, Levine AC, Sears RC, Chen EY, Duan Q, Datt M, Haider S, Ma'ayan A, DiFeo A, Sharma N, Galsky MD, Brautigan DL, Ioannou YA, Xu W, Chance MR, Ohlmeyer M, Narla G. Sangodkar J, et al. Among authors: brautigan dl. J Clin Invest. 2017 Jun 1;127(6):2081-2090. doi: 10.1172/JCI89548. Epub 2017 May 15. J Clin Invest. 2017. PMID: 28504649 Free PMC article.
Discovery and characterization of small molecules that target the GTPase Ral.
Yan C, Liu D, Li L, Wempe MF, Guin S, Khanna M, Meier J, Hoffman B, Owens C, Wysoczynski CL, Nitz MD, Knabe WE, Ahmed M, Brautigan DL, Paschal BM, Schwartz MA, Jones DN, Ross D, Meroueh SO, Theodorescu D. Yan C, et al. Among authors: brautigan dl. Nature. 2014 Nov 20;515(7527):443-7. doi: 10.1038/nature13713. Epub 2014 Sep 14. Nature. 2014. PMID: 25219851 Free PMC article.
Modulation of GSK3β autoinhibition by Thr-7 and Thr-8.
Tong Y, Park S, Wu D, Harris TE, Moskaluk CA, Brautigan DL, Fu Z. Tong Y, et al. Among authors: brautigan dl. FEBS Lett. 2018 Feb;592(4):537-546. doi: 10.1002/1873-3468.12990. Epub 2018 Feb 8. FEBS Lett. 2018. PMID: 29377106 Free PMC article.
Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors.
O'Connor CM, Leonard D, Wiredja D, Avelar RA, Wang Z, Schlatzer D, Bryson B, Tokala E, Taylor SE, Upadhyay A, Sangodkar J, Gingras AC, Westermarck J, Xu W, DiFeo A, Brautigan DL, Haider S, Jackson M, Narla G. O'Connor CM, et al. Among authors: brautigan dl. Oncogene. 2020 Jan;39(3):703-717. doi: 10.1038/s41388-019-1012-2. Epub 2019 Sep 20. Oncogene. 2020. PMID: 31541192 Free PMC article.
230 results
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