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Experimental reduction of miR-92a mimics arterial aging.

Hazra S, Henson GD, Morgan RG, Breevoort SR, Ives SJ, Richardson RS, Donato AJ, Lesniewski LA. Hazra S, et al. Among authors: breevoort sr. Exp Gerontol. 2016 Oct;83:165-70. doi: 10.1016/j.exger.2016.08.007. Epub 2016 Aug 11. Exp Gerontol. 2016. PMID: 27523918 Free PMC article.

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Expanding Clinical Spectrum of C9ORF72-Related Disorders and Promising Therapeutic Strategies: A Review.

Breevoort S, Gibson S, Figueroa K, Bromberg M, Pulst S. Breevoort S, et al. Neurol Genet. 2022 Apr 29;8(3):e670. doi: 10.1212/NXG.0000000000000670. eCollection 2022 Jun. Neurol Genet. 2022. PMID: 35620137 Free PMC article. Review.

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The pro-atherogenic response to disturbed blood flow is increased by a western diet, but not by old age.

Walker AE, Breevoort SR, Durrant JR, Liu Y, Machin DR, Dobson PS, Nielson EI, Meza AJ, Islam MT, Donato AJ, Lesniewski LA. Walker AE, et al. Among authors: breevoort sr. Sci Rep. 2019 Feb 27;9(1):2925. doi: 10.1038/s41598-019-39466-x. Sci Rep. 2019. PMID: 30814657 Free PMC article.

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Deficiency of Dab2 (Disabled Homolog 2) in Myeloid Cells Exacerbates Inflammation in Liver and Atherosclerotic Plaques in LDLR (Low-Density Lipoprotein Receptor)-Null Mice-Brief Report.

Adamson SE, Polanowska-Grabowska R, Marqueen K, Griffiths R, Angdisen J, Breevoort SR, Schulman IG, Leitinger N. Adamson SE, et al. Among authors: breevoort sr. Arterioscler Thromb Vasc Biol. 2018 May;38(5):1020-1029. doi: 10.1161/ATVBAHA.117.310467. Epub 2018 Mar 29. Arterioscler Thromb Vasc Biol. 2018. PMID: 29599136 Free PMC article.

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Macrophage-independent regulation of reverse cholesterol transport by liver X receptors.

Breevoort SR, Angdisen J, Schulman IG. Breevoort SR, et al. Arterioscler Thromb Vasc Biol. 2014 Aug;34(8):1650-60. doi: 10.1161/ATVBAHA.114.303383. Epub 2014 Jun 19. Arterioscler Thromb Vasc Biol. 2014. PMID: 24947527 Free PMC article.

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Liver LXRα expression is crucial for whole body cholesterol homeostasis and reverse cholesterol transport in mice.

Zhang Y, Breevoort SR, Angdisen J, Fu M, Schmidt DR, Holmstrom SR, Kliewer SA, Mangelsdorf DJ, Schulman IG. Zhang Y, et al. Among authors: breevoort sr. J Clin Invest. 2012 May;122(5):1688-99. doi: 10.1172/JCI59817. Epub 2012 Apr 9. J Clin Invest. 2012. PMID: 22484817 Free PMC article.

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Inhibition of the CaaX proteases Rce1p and Ste24p by peptidyl (acyloxy)methyl ketones.

Porter SB, Hildebrandt ER, Breevoort SR, Mokry DZ, Dore TM, Schmidt WK. Porter SB, et al. Among authors: breevoort sr. Biochim Biophys Acta. 2007 Jun;1773(6):853-62. doi: 10.1016/j.bbamcr.2007.03.004. Epub 2007 Mar 20. Biochim Biophys Acta. 2007. PMID: 17467817 Free PMC article.

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Proteolytic processing of certain CaaX motifs can occur in the absence of the Rce1p and Ste24p CaaX proteases.

Krishnankutty RK, Kukday SS, Castleberry AJ, Breevoort SR, Schmidt WK. Krishnankutty RK, et al. Among authors: breevoort sr. Yeast. 2009 Aug;26(8):451-63. doi: 10.1002/yea.1678. Yeast. 2009. PMID: 19504624 Free PMC article.

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Modulation of the inhibitor properties of dipeptidyl (acyloxy)methyl ketones toward the CaaX proteases.

Dechert AM, MacNamara JP, Breevoort SR, Hildebrandt ER, Hembree NW, Rea AC, McLain DE, Porter SB, Schmidt WK, Dore TM. Dechert AM, et al. Among authors: breevoort sr. Bioorg Med Chem. 2010 Sep 1;18(17):6230-7. doi: 10.1016/j.bmc.2010.07.041. Epub 2010 Jul 21. Bioorg Med Chem. 2010. PMID: 20696584 Free PMC article.

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