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CFTR modulator theratyping: Current status, gaps and future directions.

Clancy JP, Cotton CU, Donaldson SH, Solomon GM, VanDevanter DR, Boyle MP, Gentzsch M, Nick JA, Illek B, Wallenburg JC, Sorscher EJ, Amaral MD, Beekman JM, Naren AP, Bridges RJ, Thomas PJ, Cutting G, Rowe S, Durmowicz AG, Mense M, Boeck KD, Skach W, Penland C, Joseloff E, Bihler H, Mahoney J, Borowitz D, Tuggle KL. Clancy JP, et al. Among authors: bridges rj. J Cyst Fibros. 2019 Jan;18(1):22-34. doi: 10.1016/j.jcf.2018.05.004. Epub 2018 Jun 20. J Cyst Fibros. 2019. PMID: 29934203 Free PMC article. Review.

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Mechanisms of bicarbonate secretion: lessons from the airways.

Bridges RJ. Bridges RJ. Cold Spring Harb Perspect Med. 2012 Aug 1;2(8):a015016. doi: 10.1101/cshperspect.a015016. Cold Spring Harb Perspect Med. 2012. PMID: 22908201 Free PMC article. Review.

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System X_c^- Antiporter Inhibitors: Azo-Linked Amino-Naphthyl-Sulfonate Analogues of Sulfasalazine.

Nehser M, Dark J, Schweitzer D, Campbell M, Zwicker J, Hitt DM, Little H, Diaz-Correa A, Holley DC, Patel SA, Thompson CM, Bridges RJ. Nehser M, et al. Among authors: bridges rj. Neurochem Res. 2020 Jun;45(6):1375-1386. doi: 10.1007/s11064-019-02901-6. Epub 2019 Nov 21. Neurochem Res. 2020. PMID: 31754956

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Development of chloride channel modulators.

Singh AK, Venglarik CJ, Bridges RJ. Singh AK, et al. Among authors: bridges rj. Kidney Int. 1995 Oct;48(4):985-93. doi: 10.1038/ki.1995.380. Kidney Int. 1995. PMID: 8569108 Free article. Review.

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Integrative chemogenomic analysis identifies small molecules that partially rescue ΔF508-CFTR for cystic fibrosis.

Hodos RA, Strub MD, Ramachandran S, Meleshkevitch EA, Boudko DY, Bridges RJ, Dudley JT, McCray PB Jr. Hodos RA, et al. Among authors: bridges rj. CPT Pharmacometrics Syst Pharmacol. 2021 May;10(5):500-510. doi: 10.1002/psp4.12626. Epub 2021 May 2. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 33934548 Free PMC article.

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Sulfasalazine for brain cancer fits.

Sontheimer H, Bridges RJ. Sontheimer H, et al. Among authors: bridges rj. Expert Opin Investig Drugs. 2012 May;21(5):575-8. doi: 10.1517/13543784.2012.670634. Epub 2012 Mar 12. Expert Opin Investig Drugs. 2012. PMID: 22404218 Free PMC article.

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Mechanistic analysis and significance of sphingomyelinase-mediated decreases in transepithelial CFTR currents in nHBEs.

Cottrill KA, Giacalone VD, Margaroli C, Bridges RJ, Koval M, Tirouvanziam R, McCarty NA. Cottrill KA, et al. Among authors: bridges rj. Physiol Rep. 2021 Sep;9(17):e15023. doi: 10.14814/phy2.15023. Physiol Rep. 2021. PMID: 34514718 Free PMC article.

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Inhibition of the Vesicular Glutamate Transporter (VGLUT) with Congo Red Analogs: New Binding Insights.

Hitt DM, Zwicker JD, Chao CK, Patel SA, Gerdes JM, Bridges RJ, Thompson CM. Hitt DM, et al. Among authors: bridges rj. Neurochem Res. 2021 Mar;46(3):494-503. doi: 10.1007/s11064-020-03182-0. Epub 2021 Jan 4. Neurochem Res. 2021. PMID: 33398639 Free PMC article.

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Adverse events associated with endoscopic retrograde cholangiopancreatography: protocol for a systematic review and meta-analysis.

Forbes N, Leontiadis GI, Vaska M, Elmunzer BJ, Yuan Y, Bishay K, Meng ZW, Iannuzzi J, O'Sullivan DE, Mah B, Partridge ACR, Henderson AM, Qureshi A, Keswani RN, Wani S, Bridges RJ, Heitman SJ, Hilsden RJ, Ruan Y, Brenner DR. Forbes N, et al. Among authors: bridges rj. BMJ Open. 2021 Aug 17;11(8):e053302. doi: 10.1136/bmjopen-2021-053302. BMJ Open. 2021. PMID: 34404717 Free PMC article.

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Pharmacology of CFTR chloride channel activity.

Schultz BD, Singh AK, Devor DC, Bridges RJ. Schultz BD, et al. Among authors: bridges rj. Physiol Rev. 1999 Jan;79(1 Suppl):S109-44. doi: 10.1152/physrev.1999.79.1.S109. Physiol Rev. 1999. PMID: 9922378 Free article. Review.

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