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Altering Metabolic Profiles of Drugs by Precision Deuteration 2: Discovery of a Deuterated Analog of Ivacaftor with Differentiated Pharmacokinetics for Clinical Development.
Harbeson SL, Morgan AJ, Liu JF, Aslanian AM, Nguyen S, Bridson GW, Brummel CL, Wu L, Tung RD, Pilja L, Braman V, Uttamsingh V. Harbeson SL, et al. Among authors: bridson gw. J Pharmacol Exp Ther. 2017 Aug;362(2):359-367. doi: 10.1124/jpet.117.241497. Epub 2017 Jun 13. J Pharmacol Exp Ther. 2017. PMID: 28611092 Clinical Trial.
Dual Therapeutic Effects of C-10068, a Dextromethorphan Derivative, Against Post-Traumatic Nonconvulsive Seizures and Neuroinflammation in a Rat Model of Penetrating Ballistic-Like Brain Injury.
Lu XC, Shear DA, Graham PB, Bridson GW, Uttamsingh V, Chen Z, Leung LY, Tortella FC. Lu XC, et al. Among authors: bridson gw. J Neurotrauma. 2015 Oct 15;32(20):1621-32. doi: 10.1089/neu.2014.3766. Epub 2015 Jun 11. J Neurotrauma. 2015. PMID: 25794265 Free PMC article.