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Page 1
Malonate Promotes Adult Cardiomyocyte Proliferation and Heart Regeneration.
Bae J, Salamon RJ, Brandt EB, Paltzer WG, Zhang Z, Britt EC, Hacker TA, Fan J, Mahmoud AI. Bae J, et al. Among authors: britt ec. Circulation. 2021 May 18;143(20):1973-1986. doi: 10.1161/CIRCULATIONAHA.120.049952. Epub 2021 Mar 5. Circulation. 2021. PMID: 33666092 Free PMC article.
A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway.
Ghergurovich JM, García-Cañaveras JC, Wang J, Schmidt E, Zhang Z, TeSlaa T, Patel H, Chen L, Britt EC, Piqueras-Nebot M, Gomez-Cabrera MC, Lahoz A, Fan J, Beier UH, Kim H, Rabinowitz JD. Ghergurovich JM, et al. Among authors: britt ec. Nat Chem Biol. 2020 Jul;16(7):731-739. doi: 10.1038/s41589-020-0533-x. Epub 2020 May 11. Nat Chem Biol. 2020. PMID: 32393898 Free PMC article.
Metabolic regulation of epigenetic remodeling in immune cells.
Britt EC, John SV, Locasale JW, Fan J. Britt EC, et al. Curr Opin Biotechnol. 2020 Jun;63:111-117. doi: 10.1016/j.copbio.2019.12.008. Epub 2020 Jan 15. Curr Opin Biotechnol. 2020. PMID: 31954223 Free PMC article. Review.
Activation induces shift in nutrient utilization that differentially impacts cell functions in human neutrophils.
Britt EC, Qing X, Votava JA, Lika J, Wagner A, Shen S, Arp NL, Khan H, Schieke SM, Fletcher CD, Huttenlocher A, Fan J. Britt EC, et al. bioRxiv [Preprint]. 2023 Oct 28:2023.09.25.559385. doi: 10.1101/2023.09.25.559385. bioRxiv. 2023. Update in: Proc Natl Acad Sci U S A. 2024 Sep 24;121(39):e2321212121. doi: 10.1073/pnas.2321212121 PMID: 37808750 Free PMC article. Updated. Preprint.