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DiPOA ([8-(3,3-diphenyl-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-yl]-acetic acid), a novel, systemically available, and peripherally restricted Mu opioid agonist with antihyperalgesic activity: II. In vivo pharmacological characterization in the rat.
Whiteside GT, Harrison JE, Pearson MS, Chen Z, Fundytus ME, Rotshteyn Y, Turchin PI, Pomonis JD, Mark L, Walker K, Broglé KC. Whiteside GT, et al. Among authors: brogle kc. J Pharmacol Exp Ther. 2004 Aug;310(2):793-9. doi: 10.1124/jpet.103.063560. Epub 2004 Mar 30. J Pharmacol Exp Ther. 2004. PMID: 15054116
DiPOA ([8-(3,3-diphenyl-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-yl]-acetic acid), a novel, systemically available, and peripherally restricted mu opioid agonist with antihyperalgesic activity: I. In vitro pharmacological characterization and pharmacokinetic properties.
Valenzano KJ, Miller W, Chen Z, Shan S, Crumley G, Victory SF, Davies E, Huang JC, Allie N, Nolan SJ, Rotshteyn Y, Kyle DJ, Broglé K. Valenzano KJ, et al. Among authors: brogle k. J Pharmacol Exp Ther. 2004 Aug;310(2):783-92. doi: 10.1124/jpet.103.063313. Epub 2004 Mar 30. J Pharmacol Exp Ther. 2004. PMID: 15054115