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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1939 1
1947 1
1948 2
1952 1
1956 2
1958 1
1959 3
1961 2
1963 1
1964 1
1967 1
1968 1
1969 3
1970 3
1972 2
1973 3
1974 2
1975 6
1976 7
1977 4
1978 5
1979 3
1980 2
1981 4
1982 4
1983 4
1984 2
1985 4
1986 4
1987 6
1988 4
1989 3
1990 11
1991 4
1992 3
1993 5
1994 16
1995 10
1996 17
1997 19
1998 15
1999 11
2000 14
2001 8
2002 11
2003 12
2004 12
2005 12
2006 17
2007 15
2008 20
2009 21
2010 19
2011 18
2012 27
2013 27
2014 30
2015 23
2016 19
2017 28
2018 27
2019 29
2020 25
2021 17
2022 20
2023 17
2024 8

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635 results

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Page 1
Investigating the pharmacodynamic durability of GalNAc-siRNA conjugates.
Brown CR, Gupta S, Qin J, Racie T, He G, Lentini S, Malone R, Yu M, Matsuda S, Shulga-Morskaya S, Nair AV, Theile CS, Schmidt K, Shahraz A, Goel V, Parmar RG, Zlatev I, Schlegel MK, Nair JK, Jayaraman M, Manoharan M, Brown D, Maier MA, Jadhav V. Brown CR, et al. Nucleic Acids Res. 2020 Dec 2;48(21):11827-11844. doi: 10.1093/nar/gkaa670. Nucleic Acids Res. 2020. PMID: 32808038 Free PMC article.
Reply.
Smith BJ, Bolster MB, Slusher B, Stamatos C, Scott JR, Benham H, Kazi S, Schlenk EA, Schaffer DE, Majithia V, Brown CR Jr,, Von Feldt JM, Flood J, Haag DM, Smarr KL. Smith BJ, et al. Arthritis Care Res (Hoboken). 2019 Oct;71(10):1398-1399. doi: 10.1002/acr.23895. Epub 2019 Aug 23. Arthritis Care Res (Hoboken). 2019. PMID: 30927510 No abstract available.
From bench to bedside: Improving the clinical safety of GalNAc-siRNA conjugates using seed-pairing destabilization.
Schlegel MK, Janas MM, Jiang Y, Barry JD, Davis W, Agarwal S, Berman D, Brown CR, Castoreno A, LeBlanc S, Liebow A, Mayo T, Milstein S, Nguyen T, Shulga-Morskaya S, Hyde S, Schofield S, Szeto J, Woods LB, Yilmaz VO, Manoharan M, Egli M, Charissé K, Sepp-Lorenzino L, Haslett P, Fitzgerald K, Jadhav V, Maier MA. Schlegel MK, et al. Among authors: brown cr. Nucleic Acids Res. 2022 Jul 8;50(12):6656-6670. doi: 10.1093/nar/gkac539. Nucleic Acids Res. 2022. PMID: 35736224 Free PMC article.
Advanced siRNA Designs Further Improve In Vivo Performance of GalNAc-siRNA Conjugates.
Foster DJ, Brown CR, Shaikh S, Trapp C, Schlegel MK, Qian K, Sehgal A, Rajeev KG, Jadhav V, Manoharan M, Kuchimanchi S, Maier MA, Milstein S. Foster DJ, et al. Among authors: brown cr. Mol Ther. 2018 Mar 7;26(3):708-717. doi: 10.1016/j.ymthe.2017.12.021. Epub 2018 Jan 4. Mol Ther. 2018. PMID: 29456020 Free PMC article.
Reply.
Smith BJ, Bolster MB, Slusher B, Stamatos C, Scott JR, Benham H, Kazi S, Schlenk EA, Schaffer DE, Majithia V, Brown CR, Von Feldt JM, Flood J, Haag DM, Smarr KL. Smith BJ, et al. Among authors: brown cr. Arthritis Care Res (Hoboken). 2019 Aug;71(8):1147-1148. doi: 10.1002/acr.23699. Epub 2019 Jul 4. Arthritis Care Res (Hoboken). 2019. PMID: 29999241 No abstract available.
Impact of enhanced metabolic stability on pharmacokinetics and pharmacodynamics of GalNAc-siRNA conjugates.
Nair JK, Attarwala H, Sehgal A, Wang Q, Aluri K, Zhang X, Gao M, Liu J, Indrakanti R, Schofield S, Kretschmer P, Brown CR, Gupta S, Willoughby JLS, Boshar JA, Jadhav V, Charisse K, Zimmermann T, Fitzgerald K, Manoharan M, Rajeev KG, Akinc A, Hutabarat R, Maier MA. Nair JK, et al. Among authors: brown cr. Nucleic Acids Res. 2017 Nov 2;45(19):10969-10977. doi: 10.1093/nar/gkx818. Nucleic Acids Res. 2017. PMID: 28981809 Free PMC article.
Curb Your Enthusiasm.
Brown CR, Cevasco M. Brown CR, et al. Ann Thorac Surg. 2021 Oct;112(4):1217. doi: 10.1016/j.athoracsur.2020.12.053. Epub 2021 Jan 29. Ann Thorac Surg. 2021. PMID: 33524344 No abstract available.
Amyloidosis and Considerations for the Hand Surgeon.
Brown CR, Bergin JD, Deal DN. Brown CR, et al. J Hand Surg Am. 2024 Mar;49(3):260-266. doi: 10.1016/j.jhsa.2023.10.013. Epub 2023 Dec 2. J Hand Surg Am. 2024. PMID: 38043036 Review.
635 results