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Anticancer benzoxaboroles block pre-mRNA processing by directly inhibiting CPSF3.
Tao Y, Budhipramono A, Huang J, Fang M, Xie S, Kim J, Khivansara V, Dominski Z, Tong L, De Brabander JK, Nijhawan D. Tao Y, et al. Among authors: budhipramono a. Cell Chem Biol. 2024 Jan 18;31(1):139-149.e14. doi: 10.1016/j.chembiol.2023.10.019. Epub 2023 Nov 14. Cell Chem Biol. 2024. PMID: 37967558
A Medicinal Chemistry-Driven Approach Identified the Sterol Isomerase EBP as the Molecular Target of TASIN Colorectal Cancer Toxins.
Theodoropoulos PC, Wang W, Budhipramono A, Thompson BM, Madhusudhan N, Mitsche MA, McDonald JG, De Brabander JK, Nijhawan D. Theodoropoulos PC, et al. Among authors: budhipramono a. J Am Chem Soc. 2020 Apr 1;142(13):6128-6138. doi: 10.1021/jacs.9b13407. Epub 2020 Mar 19. J Am Chem Soc. 2020. PMID: 32163279 Free PMC article.
Arid1b haploinsufficient mice reveal neuropsychiatric phenotypes and reversible causes of growth impairment.
Celen C, Chuang JC, Luo X, Nijem N, Walker AK, Chen F, Zhang S, Chung AS, Nguyen LH, Nassour I, Budhipramono A, Sun X, Bok LA, McEntagart M, Gevers EF, Birnbaum SG, Eisch AJ, Powell CM, Ge WP, Santen GW, Chahrour M, Zhu H. Celen C, et al. Among authors: budhipramono a. Elife. 2017 Jul 11;6:e25730. doi: 10.7554/eLife.25730. Elife. 2017. PMID: 28695822 Free PMC article.
EGF Receptor and mTORC1 Are Novel Therapeutic Targets in Nonseminomatous Germ Cell Tumors.
Chen KS, Fustino NJ, Shukla AA, Stroup EK, Budhipramono A, Ateek C, Stuart SH, Yamaguchi K, Kapur P, Frazier AL, Lum L, Looijenga LHJ, Laetsch TW, Rakheja D, Amatruda JF. Chen KS, et al. Among authors: budhipramono a. Mol Cancer Ther. 2018 May;17(5):1079-1089. doi: 10.1158/1535-7163.MCT-17-0137. Epub 2018 Feb 26. Mol Cancer Ther. 2018. PMID: 29483210 Free PMC article.