Buecheler JW[au] - Search Results

Year	Number of Results
2018	4
2019	3
2020	2
2021	3
2022	3

1

Alteration of Physicochemical Properties for Antibody-Drug Conjugates and Their Impact on Stability.

Buecheler JW, Winzer M, Weber C, Gieseler H. Buecheler JW, et al. J Pharm Sci. 2020 Jan;109(1):161-168. doi: 10.1016/j.xphs.2019.08.006. Epub 2019 Aug 10. J Pharm Sci. 2020. PMID: 31408634 Review.

2

Oxidation-Induced Destabilization of Model Antibody-Drug Conjugates.

Buecheler JW, Winzer M, Weber C, Gieseler H. Buecheler JW, et al. J Pharm Sci. 2019 Mar;108(3):1236-1245. doi: 10.1016/j.xphs.2018.10.039. Epub 2018 Oct 30. J Pharm Sci. 2019. PMID: 30389566

3

Impact of Payload Hydrophobicity on the Stability of Antibody-Drug Conjugates.

Buecheler JW, Winzer M, Tonillo J, Weber C, Gieseler H. Buecheler JW, et al. Mol Pharm. 2018 Jul 2;15(7):2656-2664. doi: 10.1021/acs.molpharmaceut.8b00177. Epub 2018 Jun 6. Mol Pharm. 2018. PMID: 29809017

4

Scaling Down Large-Scale Thawing of Monoclonal Antibody Solutions: 3D Temperature Profiles, Changes in Concentration, and Density Gradients.

Bluemel O, Buecheler JW, Hauptmann A, Hoelzl G, Bechtold-Peters K, Friess W. Bluemel O, et al. Among authors: buecheler jw. Pharm Res. 2021 Nov;38(11):1977-1989. doi: 10.1007/s11095-021-03117-6. Epub 2021 Nov 2. Pharm Res. 2021. PMID: 34729702 Free PMC article.

5

Cryoconcentration and 3D Temperature Profiles During Freezing of mAb Solutions in Large-Scale PET Bottles and a Novel Scale-Down Device.

Bluemel O, Buecheler JW, Rodrigues MA, Geraldes V, Hoelzl G, Bechtold-Peters K, Friess W. Bluemel O, et al. Among authors: buecheler jw. Pharm Res. 2020 Aug 30;37(9):179. doi: 10.1007/s11095-020-02886-w. Pharm Res. 2020. PMID: 32864719

6

High-throughput oxidation screen of antibody-drug conjugates by analytical protein A chromatography following IdeS digest.

Buecheler JW, Winzer M, Weber C, Gieseler H. Buecheler JW, et al. J Pharm Pharmacol. 2018 May;70(5):625-635. doi: 10.1111/jphp.12873. Epub 2018 Jan 30. J Pharm Pharmacol. 2018. PMID: 29380379

7

Residual Seal Force Testing: A Suitable Method for Seal Quality Determination of (High Potent) Parenterals.

Buecheler JW, Luemkemann J, Gieseler H, Mohl S, Streubel A. Buecheler JW, et al. PDA J Pharm Sci Technol. 2019 Mar-Apr;73(2):111-120. doi: 10.5731/pdajpst.2018.008870. Epub 2018 Oct 25. PDA J Pharm Sci Technol. 2019. PMID: 30361287

8

Evaluation of Two Novel Scale-Down Devices for Testing Monoclonal Antibody Aggregation During Large-Scale Freezing.

Bluemel O, Rodrigues MA, Buecheler JW, Geraldes V, Hoelzl G, Hauptmann A, Bechtold-Peters K, Friess W. Bluemel O, et al. Among authors: buecheler jw. J Pharm Sci. 2022 Jul;111(7):1973-1983. doi: 10.1016/j.xphs.2022.01.003. Epub 2022 Jan 8. J Pharm Sci. 2022. PMID: 35007568

9

The effect of mAb and excipient cryoconcentration on long-term frozen storage stability - part 2: Aggregate formation and oxidation.

Bluemel O, Buecheler JW, Hauptmann A, Hoelzl G, Bechtold-Peters K, Friess W. Bluemel O, et al. Among authors: buecheler jw. Int J Pharm X. 2021 Dec 25;4:100109. doi: 10.1016/j.ijpx.2021.100109. eCollection 2022 Dec. Int J Pharm X. 2021. PMID: 35024604 Free PMC article.

10

The effect of mAb and excipient cryoconcentration on long-term frozen storage stability - Part 1: Higher molecular weight species and subvisible particle formation.

Bluemel O, Anuschek M, Buecheler JW, Hoelzl G, Bechtold-Peters K, Friess W. Bluemel O, et al. Among authors: buecheler jw. Int J Pharm X. 2021 Dec 25;4:100108. doi: 10.1016/j.ijpx.2021.100108. eCollection 2022 Dec. Int J Pharm X. 2021. PMID: 35024603 Free PMC article.

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