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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 1
1986 1
2000 1
2006 1
2008 1
2009 1
2011 1
2012 2
2013 2
2014 1
2016 2
2018 6
2020 4
2021 3
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26 results
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Page 1
Discovery of small molecules that bind to K-Ras and inhibit Sos-mediated activation.
Sun Q, Burke JP, Phan J, Burns MC, Olejniczak ET, Waterson AG, Lee T, Rossanese OW, Fesik SW. Sun Q, et al. Among authors: burns mc. Angew Chem Int Ed Engl. 2012 Jun 18;51(25):6140-3. doi: 10.1002/anie.201201358. Epub 2012 May 8. Angew Chem Int Ed Engl. 2012. PMID: 22566140 Free PMC article. No abstract available.
Dietary signals in the premolar dentition of primates.
Scott JE, Campbell RM, Baj LM, Burns MC, Price MS, Sykes JD, Vinyard CJ. Scott JE, et al. Among authors: burns mc. J Hum Evol. 2018 Aug;121:221-234. doi: 10.1016/j.jhevol.2018.04.006. Epub 2018 May 21. J Hum Evol. 2018. PMID: 29793792
Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS.
Abbott JR, Patel PA, Howes JE, Akan DT, Kennedy JP, Burns MC, Browning CF, Sun Q, Rossanese OW, Phan J, Waterson AG, Fesik SW. Abbott JR, et al. Among authors: burns mc. ACS Med Chem Lett. 2018 Aug 8;9(9):941-946. doi: 10.1021/acsmedchemlett.8b00296. eCollection 2018 Sep 13. ACS Med Chem Lett. 2018. PMID: 30258545 Free PMC article.
Pembrolizumab for the treatment of advanced melanoma.
Burns MC, O'Donnell A, Puzanov I. Burns MC, et al. Expert Opin Orphan Drugs. 2016;4(8):867-873. doi: 10.1080/21678707.2016.1191348. Epub 2016 Jun 7. Expert Opin Orphan Drugs. 2016. PMID: 27597930 Free PMC article.
Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS.
Hodges TR, Abbott JR, Little AJ, Sarkar D, Salovich JM, Howes JE, Akan DT, Sai J, Arnold AL, Browning C, Burns MC, Sobolik T, Sun Q, Beesetty Y, Coker JA, Scharn D, Stadtmueller H, Rossanese OW, Phan J, Waterson AG, McConnell DB, Fesik SW. Hodges TR, et al. Among authors: burns mc. J Med Chem. 2018 Oct 11;61(19):8875-8894. doi: 10.1021/acs.jmedchem.8b01108. Epub 2018 Sep 28. J Med Chem. 2018. PMID: 30205005
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