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1973 1
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15,023 results

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Page 1
Photo-Induced C-H Methylation Reactions.
Li QY, He Y, Lin YM, Gong L. Li QY, et al. Chemistry. 2023 Dec 22;29(72):e202302542. doi: 10.1002/chem.202302542. Epub 2023 Nov 10. Chemistry. 2023. PMID: 37800464 Review.
Direct C-H methylation is a highly valuable approach for introducing methyl groups into organic molecules, particularly in pharmaceutical chemistry. ...This article offers a comprehensive review of photochemical strategies employed for the direct and selective methylation …
Direct C-H methylation is a highly valuable approach for introducing methyl groups into organic molecules, particularly in pharmaceut …
Jiawei Qi Gong Wan improves liver fibrosis and inflammation in PCOS mice via the Akt2-FoxO1 and YAP/TAZ signaling pathways.
Li J, Zheng R, Shen Y, Zhuo Y, Lu L, Song J, Li J, Lai M, Zhu H, Hu M, Ma H, Li J. Li J, et al. Phytomedicine. 2025 Jan;136:156294. doi: 10.1016/j.phymed.2024.156294. Epub 2024 Nov 30. Phytomedicine. 2025. PMID: 39616732
However, little is known about whether PCOS is associated with more severe NAFLD histopathology. Although Jiawei Qi Gong Wan (JQGW) is widely used clinically, its specific effects and mechanisms on the liver remain unclear. ...
However, little is known about whether PCOS is associated with more severe NAFLD histopathology. Although Jiawei Qi Gong Wan (JQGW) i …
Identification of C-geranylated flavonoids from Paulownia catalpifolia Gong Tong fruits by HPLC-DAD-ESI-MS/MS and their anti-aging effects on 2BS cells induced by H(2)O(2).
Tang WZ, Wang YA, Gao TY, Wang XJ, Zhao YX. Tang WZ, et al. Chin J Nat Med. 2017 May;15(5):384-391. doi: 10.1016/S1875-5364(17)30059-6. Chin J Nat Med. 2017. PMID: 28558874 Free PMC article.
Our previous study has identified new C-geranylated flavanones with obvious anti-proliferative effects in lung cancer A549 cells. In the present study, a new C-geranylated flavone, paucatalinone C (1) and five known C-geranylated flavanones (2-6) were …
Our previous study has identified new C-geranylated flavanones with obvious anti-proliferative effects in lung cancer A549 cells. In …
Sulfuration of unreactive C-H bonds.
Gong HW, Tang HT, Pan YM. Gong HW, et al. Chem Commun (Camb). 2025 Jun 10;61(48):8643-8654. doi: 10.1039/d5cc01794g. Chem Commun (Camb). 2025. PMID: 40395072 Review.
This methodology enables the efficient construction of C-S bonds through direct activation of high bond energy C-H bonds, substantially enhancing both synthetic efficiency and atom economy for sulfur-containing compounds. This review systematically summarizes the st …
This methodology enables the efficient construction of C-S bonds through direct activation of high bond energy C-H bonds, subs …
Structure of mycobacterial ergothioneine-biosynthesis C-S lyase EgtE.
Wei L, Liu L, Gong W. Wei L, et al. J Biol Chem. 2024 Jan;300(1):105539. doi: 10.1016/j.jbc.2023.105539. Epub 2023 Dec 10. J Biol Chem. 2024. PMID: 38072054 Free PMC article.
One of the key steps in the ergothioneine-biosynthesis pathway, the C-S bond cleavage reaction, uses the pyridoxal 5'-phosphate dependent C-S lyase to produce the final product L-ergothioneine. Here, we present the crystallographic structure of the ergothioneine-bio …
One of the key steps in the ergothioneine-biosynthesis pathway, the C-S bond cleavage reaction, uses the pyridoxal 5'-phosphate depen …
(1R,3S,4R,4aS,7R,7aS,10R,12aR)-3-Azido-4,7,10-trimethyl-1,10-epidioxy-per-hydropyrano[4,3-j][1,2]benzodiox-epine.
Xie L, Zhai X, Zuo J, Zhao Y, Gong P. Xie L, et al. Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 26;66(Pt 7):o1839. doi: 10.1107/S1600536810024566. Acta Crystallogr Sect E Struct Rep Online. 2010. PMID: 21588040 Free PMC article.
In the title compound, C(15)H(23)N(3)O(4), the six-membered pyran, cyclo-hexane and trioxane rings adopt chair, chair and boat conformations, respectively, while the seven-membered rings adopt distorted boat and very distorted chair conformations. In the crystal, adjacent …
In the title compound, C(15)H(23)N(3)O(4), the six-membered pyran, cyclo-hexane and trioxane rings adopt chair, chair and boat confor …
4-(2-Hydroxy-benzyl-idene-amino)-benzonitrile.
Gong XX, Xu HJ. Gong XX, et al. Acta Crystallogr Sect E Struct Rep Online. 2008 Jun 7;64(Pt 7):o1188. doi: 10.1107/S160053680801564X. Acta Crystallogr Sect E Struct Rep Online. 2008. PMID: 21202830 Free PMC article.
The mol-ecule of the title compound, C(14)H(10)N(2)O, is nearly planar. There is a strong intra-molecular O-HN hydrogen bond between the imine and hydr-oxy groups. The configuration with respect to the C=N double bond is anti (1E)....
The mol-ecule of the title compound, C(14)H(10)N(2)O, is nearly planar. There is a strong intra-molecular O-HN hydrogen bond between …
2-(2-Hydroxy-benzyl-ideneamino)benzonitrile.
Xia R, Xu HJ, Gong XX. Xia R, et al. Acta Crystallogr Sect E Struct Rep Online. 2008 May 10;64(Pt 6):o1047. doi: 10.1107/S160053680801163X. Acta Crystallogr Sect E Struct Rep Online. 2008. PMID: 21202566 Free PMC article.
The mol-ecule of the title compound, C(14)H(10)N(2)O, displays a trans configuration with respect to the C=N double bond. ...
The mol-ecule of the title compound, C(14)H(10)N(2)O, displays a trans configuration with respect to the C=N double bond. ...
Selectfluor-enabled photochemical selective C(sp(3))-H(sulfonyl)amidation.
Chen Y, Yang B, Li QY, Lin YM, Gong L. Chen Y, et al. Chem Commun (Camb). 2022 Dec 22;59(1):118-121. doi: 10.1039/d2cc05569d. Chem Commun (Camb). 2022. PMID: 36477311
Transition metal- and photosensitizer-free C(sp(3))-H (sulfonyl)amidation reactions have been realized by employing Selectfluor as a versatile reagent, functioning as a photoactive component, a HAT precursor and an oxidant. ...
Transition metal- and photosensitizer-free C(sp(3))-H (sulfonyl)amidation reactions have been realized by employing Selectfluor as a …
Undescribed C-geranylflavonoids isolated from the fruit peel of Paulownia catalpifolia T. Gong ex D.Y. Hong with their protection on human umbilical vein endothelial cells injury induced by hydrogen peroxide.
Wang YA, Guo X, Jia XH, Xue J, Du HF, Du CL, Tang WZ, Wang XJ, Zhao YX. Wang YA, et al. Phytochemistry. 2019 Feb;158:126-134. doi: 10.1016/j.phytochem.2018.11.010. Epub 2018 Dec 5. Phytochemistry. 2019. PMID: 30529863
Six undescribed C-geranylated flavonoids, including five C-geranylflavanones named as paucatalinones F - J, one C-geranylflavonol named as paucatalinone K, along with seven known geranylated flavanones, were isolated from the fruit peel of Paulownia catalpifo …
Six undescribed C-geranylated flavonoids, including five C-geranylflavanones named as paucatalinones F - J, one C-geran …
15,023 results
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