In vivo study to evaluate the protective effects of amifostine on radiation-induced damage of testis tissue.
Andrieu MN, Kurtman C, Hicsonmez A, Ozbilgin K, Eser E, Erdemli E.
Andrieu MN, et al.
Oncology. 2005;69(1):44-51. doi: 10.1159/000087475. Epub 2005 Aug 12.
Oncology. 2005.
PMID: 16103734
METHODS: Eighty adult male Wistar rats were randomized to 4 groups: Saline solution was given to group A for control, 200 mg/kg amifostine (WR-2721) to group B, a single fraction of 6 Gy local irradiation to testes in group C and 200 mg/kg amifostine 15-30 min before 6 Gy …
METHODS: Eighty adult male Wistar rats were randomized to 4 groups: Saline solution was given to group A for control, 200 mg/kg amifostine ( …