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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 1
1996 1
1997 3
2002 2
2003 1
2004 3
2005 5
2006 6
2007 3
2008 6
2009 10
2010 15
2011 15
2012 13
2013 20
2014 23
2015 26
2016 35
2017 57
2018 53
2019 71
2020 96
2021 99
2022 82
2023 96
2024 120
2025 131
2026 13

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886 results

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Page 1
CD4+ T cells contribute to neurodegeneration in Lewy body dementia.
Gate D, Tapp E, Leventhal O, Shahid M, Nonninger TJ, Yang AC, Strempfl K, Unger MS, Fehlmann T, Oh H, Channappa D, Henderson VW, Keller A, Aigner L, Galasko DR, Davis MM, Poston KL, Wyss-Coray T. Gate D, et al. Science. 2021 Nov 12;374(6569):868-874. doi: 10.1126/science.abf7266. Epub 2021 Oct 14. Science. 2021. PMID: 34648304 Free PMC article.
Single-cell RNA sequencing of cerebrospinal fluid (CSF) identified up-regulated expression of C-X-C motif chemokine receptor 4 (CXCR4) in CD4(+) T cells in LBD. CSF protein levels of the CXCR4 ligand, C-X-C motif chemokine ligand 12 (CXCL12), were asso …
Single-cell RNA sequencing of cerebrospinal fluid (CSF) identified up-regulated expression of C-X-C motif chemokine receptor 4 …
CXCL12/CXCR4: An amazing challenge and opportunity in the fight against fibrosis.
Wu X, Qian L, Zhao H, Lei W, Liu Y, Xu X, Li J, Yang Z, Wang D, Zhang Y, Zhang Y, Tang R, Yang Y, Tian Y. Wu X, et al. Ageing Res Rev. 2023 Jan;83:101809. doi: 10.1016/j.arr.2022.101809. Epub 2022 Nov 25. Ageing Res Rev. 2023. PMID: 36442720 Review.
Aging is an important risk factor for the development of organ fibrosis. C-X-C receptor 4 (CXCR4) is the predominant chemokine receptor on fibrocytes, C-X-C motif ligand 12 (CXCL12) is the only ligand of CXCR4. ...
Aging is an important risk factor for the development of organ fibrosis. C-X-C receptor 4 (CXCR4) is the predominant chemokine …
Signaling pathways and targeted therapy for rosacea.
Yang F, Wang L, Song D, Zhang L, Wang X, Du D, Jiang X. Yang F, et al. Front Immunol. 2024 Sep 16;15:1367994. doi: 10.3389/fimmu.2024.1367994. eCollection 2024. Front Immunol. 2024. PMID: 39351216 Free PMC article. Review.
LL37 interacts with signaling molecules such as extracellular signal-regulated kinases 1 and 2 (ERK1/2), nuclear factor kappa B (NF-kappaB), inflammasomes, C-X-C motif chemokine ligand 8 (CXCL8), mas-related G-protein-coupled receptor X2 (MRGPRX2)-TRPV4, and vascula …
LL37 interacts with signaling molecules such as extracellular signal-regulated kinases 1 and 2 (ERK1/2), nuclear factor kappa B (NF-kappaB), …
Targeting ESE3/EHF With Nifurtimox Inhibits CXCR2+ Neutrophil Infiltration and Overcomes Pancreatic Cancer Resistance to Chemotherapy and Immunotherapy.
Xie Y, Zhou T, Li X, Zhao K, Bai W, Hou X, Liu Z, Ni B, Zhang Z, Yan J, Wang Y, Jiang W, Wang H, Chang A, Gao S, Zhao T, Yang S, Huang C, Liu J, Hao J. Xie Y, et al. Gastroenterology. 2024 Jul;167(2):281-297. doi: 10.1053/j.gastro.2024.02.046. Epub 2024 Mar 15. Gastroenterology. 2024. PMID: 38492894
Multiplexed immunohistochemistry and flow cytometry were performed to investigate the proportion of tumor-infiltrated C-X-C motif chemokine receptor 2 (CXCR2)(+) neutrophils. In addition, multiplexed cytokines assays and chromatin immunoprecipitation assays were use …
Multiplexed immunohistochemistry and flow cytometry were performed to investigate the proportion of tumor-infiltrated C-X-C mo …
Cancer-Associated Fibroblast-Mediated Cellular Crosstalk Supports Hepatocellular Carcinoma Progression.
Song M, He J, Pan QZ, Yang J, Zhao J, Zhang YJ, Huang Y, Tang Y, Wang Q, He J, Gu J, Li Y, Chen S, Zeng J, Zhou ZQ, Yang C, Han Y, Chen H, Xiang T, Weng DS, Xia JC. Song M, et al. Hepatology. 2021 May;73(5):1717-1735. doi: 10.1002/hep.31792. Hepatology. 2021. PMID: 33682185
APPROACH AND RESULTS: In the HCC-TME, CAF-derived cardiotrophin-like cytokine factor 1 (CLCF1) increased chemokine (C-X-C motif) ligand 6 (CXCL6) and TGF-beta secretion in tumor cells, which subsequently promoted tumor cell stemness in an autocrine manner and TAN in …
APPROACH AND RESULTS: In the HCC-TME, CAF-derived cardiotrophin-like cytokine factor 1 (CLCF1) increased chemokine (C-X-C moti …
Quercetin protects against sepsis-associated encephalopathy by inhibiting microglia-neuron crosstalk via the CXCL2/CXCR2 signaling pathway.
Yang YS, Liu CY, Pei MQ, Sun ZD, Lin S, He HF. Yang YS, et al. Phytomedicine. 2024 Nov;134:155987. doi: 10.1016/j.phymed.2024.155987. Epub 2024 Aug 26. Phytomedicine. 2024. PMID: 39216299
Bioinformatics analysis revealed that the C-X-C motif chemokine ligand 2 (CXCL2)/C-X-C motif chemokine receptor 2 (CXCR2) axis may play a key role in QUE-mediated protection against SAE. ...
Bioinformatics analysis revealed that the C-X-C motif chemokine ligand 2 (CXCL2)/C-X-C motif chemokine receptor …
Distinct mural cells and fibroblasts promote pathogenic plasma cell accumulation in idiopathic pulmonary fibrosis.
Yang Z, Cao G, Tan X, Orfanos S, Jude J, Barbet G, An SS, Jiang D, Panettieri RA Jr, Yang Q. Yang Z, et al. Eur Respir J. 2025 Jun 5;65(6):2401114. doi: 10.1183/13993003.01114-2024. Print 2025 Jun. Eur Respir J. 2025. PMID: 39978854
Distinct IPF-associated fibroblasts further secreted C-X-C motif chemokine ligand 12 (CXCL12), providing an extramedullary niche to foster the dissemination and accumulation of plasma cells in the fibrotic regions. ...
Distinct IPF-associated fibroblasts further secreted C-X-C motif chemokine ligand 12 (CXCL12), providing an extramedullary nic …
886 results