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The importance of Ca(2+)-dependent mechanisms for the initiation of the heartbeat.

Capel RA, Terrar DA. Capel RA, et al. Front Physiol. 2015 Mar 25;6:80. doi: 10.3389/fphys.2015.00080. eCollection 2015. Front Physiol. 2015. PMID: 25859219 Free PMC article. Review.

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Cardiac TdP risk stratification modelling of anti-infective compounds including chloroquine and hydroxychloroquine.

Whittaker DG, Capel RA, Hendrix M, Chan XHS, Herring N, White NJ, Mirams GR, Burton RB. Whittaker DG, et al. Among authors: capel ra. R Soc Open Sci. 2021 Apr 13;8(4):210235. doi: 10.1098/rsos.210235. R Soc Open Sci. 2021. PMID: 33996135 Free PMC article.

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A modified density gradient proteomic-based method to analyze endolysosomal proteins in cardiac tissue.

Ayagama T, Bose SJ, Capel RA, Priestman DA, Berridge G, Fischer R, Galione A, Platt FM, Kramer H, Burton RAB. Ayagama T, et al. Among authors: capel ra. iScience. 2021 Aug 4;24(9):102949. doi: 10.1016/j.isci.2021.102949. eCollection 2021 Sep 24. iScience. 2021. PMID: 34466782 Free PMC article.

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IP₃-mediated Ca²⁺ release regulates atrial Ca²⁺ transients and pacemaker function by stimulation of adenylyl cyclases.

Capel RA, Bose SJ, Collins TP, Rajasundaram S, Ayagama T, Zaccolo M, Burton RB, Terrar DA. Capel RA, et al. Am J Physiol Heart Circ Physiol. 2021 Jan 1;320(1):H95-H107. doi: 10.1152/ajpheart.00380.2020. Epub 2020 Oct 16. Am J Physiol Heart Circ Physiol. 2021. PMID: 33064562 Free PMC article.

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Load-dependent effects of apelin on murine cardiomyocytes.

Peyronnet R, Bollensdorff C, Capel RA, Rog-Zielinska EA, Woods CE, Charo DN, Lookin O, Fajardo G, Ho M, Quertermous T, Ashley EA, Kohl P. Peyronnet R, et al. Among authors: capel ra. Prog Biophys Mol Biol. 2017 Nov;130(Pt B):333-343. doi: 10.1016/j.pbiomolbio.2017.09.013. Epub 2017 Sep 18. Prog Biophys Mol Biol. 2017. PMID: 28935153 Free PMC article.

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Optical Interrogation of Sympathetic Neuronal Effects on Macroscopic Cardiomyocyte Network Dynamics.

Burton RB, Tomek J, Ambrosi CM, Larsen HE, Sharkey AR, Capel RA, Corbett AD, Bilton S, Klimas A, Stephens G, Cremer M, Bose SJ, Li D, Gallone G, Herring N, Mann EO, Kumar A, Kramer H, Entcheva E, Paterson DJ, Bub G. Burton RB, et al. Among authors: capel ra. iScience. 2020 Jul 24;23(7):101334. doi: 10.1016/j.isci.2020.101334. Epub 2020 Jul 1. iScience. 2020. PMID: 32674058 Free PMC article.

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Transverse cardiac slicing and optical imaging for analysis of transmural gradients in membrane potential and Ca²⁺ transients in murine heart.

Wen Q, Gandhi K, Capel RA, Hao G, O'Shea C, Neagu G, Pearcey S, Pavlovic D, Terrar DA, Wu J, Faggian G, Camelliti P, Lei M. Wen Q, et al. Among authors: capel ra. J Physiol. 2018 Sep;596(17):3951-3965. doi: 10.1113/JP276239. Epub 2018 Jul 26. J Physiol. 2018. PMID: 29928770 Free PMC article.

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High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heart.

Aston D, Capel RA, Ford KL, Christian HC, Mirams GR, Rog-Zielinska EA, Kohl P, Galione A, Burton RA, Terrar DA. Aston D, et al. Among authors: capel ra. Sci Rep. 2017 Jan 17;7:40620. doi: 10.1038/srep40620. Sci Rep. 2017. PMID: 28094777 Free PMC article.

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Hydroxychloroquine reduces heart rate by modulating the hyperpolarization-activated current If: Novel electrophysiological insights and therapeutic potential.

Capel RA, Herring N, Kalla M, Yavari A, Mirams GR, Douglas G, Bub G, Channon K, Paterson DJ, Terrar DA, Burton RA. Capel RA, et al. Heart Rhythm. 2015 Oct;12(10):2186-94. doi: 10.1016/j.hrthm.2015.05.027. Epub 2015 May 27. Heart Rhythm. 2015. PMID: 26025323 Free PMC article.

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Mapping cardiac microstructure of rabbit heart in different mechanical states by high resolution diffusion tensor imaging: A proof-of-principle study.

Teh I, Burton RA, McClymont D, Capel RA, Aston D, Kohl P, Schneider JE. Teh I, et al. Among authors: capel ra. Prog Biophys Mol Biol. 2016 Jul;121(2):85-96. doi: 10.1016/j.pbiomolbio.2016.06.001. Epub 2016 Jun 16. Prog Biophys Mol Biol. 2016. PMID: 27320383 Free PMC article.

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